;X-RAY CRYSTAL STRUCTURE OF THE PROTEASE INHIBITOR DOMAIN OF ALZHEIMER'S AMYLOID BETA-PROTEIN PRECURSOR ;

Method: X-RAY DIFFRACTION D_max: 54.3 Å Quality: GOOD

SAXS Profile

P(r) Distribution

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1. Structure Basics

entry_id	1aap
deposition_date	1990-09-14
title	;X-RAY CRYSTAL STRUCTURE OF THE PROTEASE INHIBITOR DOMAIN OF ALZHEIMER'S AMYLOID BETA-PROTEIN PRECURSOR ;
keywords	PROTEINASE INHIBITOR (TRYPSIN); PROTEINASE INHIBITOR (TRYPSIN)
method	X-RAY DIFFRACTION

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Download Data

SAXS curve (.dat) P(r) distribution (.pr.out) Structure (CIF)

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2. SAXS Parameters (CRYSOL)

rg_guinier	15.21 Å
rg_electron	14.50 Å
i0	3754620.00
molecular_weight	12474.0 kDa
excluded_volume	15026 Å³
envelope_volume	18035 Å³
shell_volume	10959 Å³
envelope_diameter	54.0 Å
shell_rg	19.41 Å
envelope_rg	14.70 Å
shape_rg	14.44 Å
total_rg	15.62 Å
total_atoms	866
n_residues	112
n_harmonics	20
q_range	— – 0.5000 Å⁻¹
n_points	101
shell_type	directional
solvent_density	0.3340 e/Å³
contrast_shell	0.0300 e/Å³
crysol_version	4.1.3

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3. P(r) Analysis (GNOM)

dmax	54.3 Å
rg_real	15.18 Å
rg_real_error	0.33 Å
i0_real	3.7550e+06
i0_real_error	3.9110e+04
rg_reciprocal	15.19 Å
i0_reciprocal	3755000.0000
total_estimate	0.8589
solution_quality	GOOD a GOOD solution
n_peaks	2
r_peak_primary	17.9 Å
skewness	0.279
kurtosis	-0.361
angular_range	— – 0.5000 Å⁻¹
current_alpha	0.0000
highest_alpha	1155000.0000
n_real_points	80
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.763; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.879; Smooth: 0.994

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4. Crystallography & Experiment

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5. Entities & Polymer Info (2)

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6. Citations (1)

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length_a	35.600 Å
length_b	38.900 Å
length_c	73.600 Å
angle_alpha	90.00 °
angle_beta	90.00 °
angle_gamma	90.00 °
z_pdb	8

space_group	P 21 21 21
int_tables_number	19
crystal_system	—

resolution	1.500 Å
resolution_low	8.000 Å
r_factor	0.1770
r_work	—
r_free	—

description	;ALZHEIMER'S DISEASE AMYLOID A4 PROTEIN ;
formula_weight	6420.1 kDa
src_method	man
entity_count	2

type	polypeptide(L)
strand_id	A,B
atom_count	971

;X-RAY CRYSTAL STRUCTURE OF THE PROTEASE INHIBITOR DOMAIN OF ALZHEIMER'S AMYLOID BETA-PROTEIN PRECURSOR ;

SAXS Profile

P(r) Distribution

1. Structure Basics

Download Data

2. SAXS Parameters (CRYSOL)

3. P(r) Analysis (GNOM)

4. Crystallography & Experiment

Unit Cell

Symmetry

Refinement

5. Entities & Polymer Info (2)

Entity 1 polymer

Polymer

Source

Entity 2 water

6. Citations (1)

7. Files & Curves (10)

Files (7)

Curves (3)

organism	Homo sapiens
common_name	human
ncbi_taxonomy_id	9606
host_organism	Escherichia coli

description	water
formula_weight	18.0 kDa
src_method	nat
entity_count	105

fit	/app/data/saxs_computation/aa/1aap/1aap.fit
pddf	/app/data/pr_computation/aa/1aap/1aap.pr.out
profile	/app/data/saxs_computation/aa/1aap/1aap.dat