SAXSdb — 1av1

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1. Protein Identity and Related Structures Protein Identity & Related Structures

APOLIPOPROTEIN A-I

Homo sapiens

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein homooligomer	Homooligomer	Protein 4	No other associated polymer	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	APOA1_HUMAN
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain A； PDBConstruct 2–201； UniProt 68–267 Author chain B； PDBConstruct 2–201； UniProt 68–267 Author chain C； PDBConstruct 2–201； UniProt 68–267 Author chain D； PDBConstruct 2–201； UniProt 68–267

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	1av1
Deposition date deposition_date	1997-09-23
Structure title title	CRYSTAL STRUCTURE OF HUMAN APOLIPOPROTEIN A-I
Keywords keywords	LIPOPROTEIN, LIPID TRANSPORT, CHOLESTEROL METABOLISM, ATHEROSCLEROSIS, HDL, LCAT-ACTIVATION; LIPID TRANSPORT
Experimental Method method	X-RAY DIFFRACTION

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

1av1__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

1av1__assembly_1__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

1av1__assembly_1__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	50.46 Å
Rg (electron density)	50.03 Å
Total Rg	50.33 Å
Atom count	6588
Residues	804
Excluded volume	116870 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`1av1__assembly_1__model_1`	tetrameric （4）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (1)

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6. Fold Classification (SCOP + CATH) 12 domains

SCOP 2.08 (8 domains)

Domain ID domain_id	d1av1a1
Class class	h — Coiled coil proteins
Fold Fold fold	h.5 — Apolipoprotein A-I
Superfamily Superfamily superfamily	h.5.1 — Apolipoprotein A-I
Family Family family	h.5.1.1 — Apolipoprotein A-I

Domain ID domain_id	d1av1a2
Class class	l — Artifacts
Fold Fold fold	l.1 — Tags
Superfamily Superfamily superfamily	l.1.1 — Tags
Family Family family	l.1.1.1 — Tags

Domain ID domain_id	d1av1b1
Class class	h — Coiled coil proteins
Fold Fold fold	h.5 — Apolipoprotein A-I
Superfamily Superfamily superfamily	h.5.1 — Apolipoprotein A-I
Family Family family	h.5.1.1 — Apolipoprotein A-I

Domain ID domain_id	d1av1b2
Class class	l — Artifacts
Fold Fold fold	l.1 — Tags
Superfamily Superfamily superfamily	l.1.1 — Tags
Family Family family	l.1.1.1 — Tags

Domain ID domain_id	d1av1c1
Class class	h — Coiled coil proteins
Fold Fold fold	h.5 — Apolipoprotein A-I
Superfamily Superfamily superfamily	h.5.1 — Apolipoprotein A-I
Family Family family	h.5.1.1 — Apolipoprotein A-I

Domain ID domain_id	d1av1c2
Class class	l — Artifacts
Fold Fold fold	l.1 — Tags
Superfamily Superfamily superfamily	l.1.1 — Tags
Family Family family	l.1.1.1 — Tags

Domain ID domain_id	d1av1d1
Class class	h — Coiled coil proteins
Fold Fold fold	h.5 — Apolipoprotein A-I
Superfamily Superfamily superfamily	h.5.1 — Apolipoprotein A-I
Family Family family	h.5.1.1 — Apolipoprotein A-I

Domain ID domain_id	d1av1d2
Class class	l — Artifacts
Fold Fold fold	l.1 — Tags
Superfamily Superfamily superfamily	l.1.1 — Tags
Family Family family	l.1.1.1 — Tags

CATH v4.4 (4 domains)

Domain ID domain_id	1av1A00
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily	1230 — Apolipoprotein A-I

Domain ID domain_id	1av1B00
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily	1230 — Apolipoprotein A-I

Domain ID domain_id	1av1C00
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily	1230 — Apolipoprotein A-I

Domain ID domain_id	1av1D00
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily	1230 — Apolipoprotein A-I

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Unit-cell length a length_a	97.470 Å
Unit-cell length b length_b	113.870 Å
Unit-cell length c length_c	196.190 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	90.00 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	16

Space group space_group	P 21 21 21
Space-group number int_tables_number	19
Crystal system crystal_system	—

Resolution resolution	4.000 Å
Low-resolution limit resolution_low	27.000 Å
R factor r_factor	0.3820
R_work r_work	0.3820
R_free r_free	0.4280

Description description	APOLIPOPROTEIN A-I
Molecular weight formula_weight	23440.6 kDa
Mutation mutation	N-TERMINAL MET, DEL(1-43)
Source method src_method	man
Copy count entity_count	4

Polymer type type	polypeptide(L)
Chain IDs strand_id	A,B,C,D
Atom count atom_count	6588

CRYSTAL STRUCTURE OF HUMAN APOLIPOPROTEIN A-I

1. Protein Identity and Related Structures Protein Identity & Related Structures

APOLIPOPROTEIN A-I

State in the Current Structure

Other States of the Same Protein in the Database

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

1av1__assembly_1__model_1

1av1__assembly_1__model_1 | I(q)

1av1__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (1)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

6. Fold Classification (SCOP + CATH) 12 domains

SCOP 2.08 (8 domains)

CATH v4.4 (4 domains)

7. Citations (4)

Source organism organism	Homo sapiens
Common name common_name	human
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	Escherichia coli BL21(DE3)

CRYSTAL STRUCTURE OF HUMAN APOLIPOPROTEIN A-I

1. Protein Identity and Related Structures Protein Identity & Related Structures

APOLIPOPROTEIN A-I

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

1av1__assembly_1__model_1

1av1__assembly_1__model_1 | I(q)

1av1__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (1)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

6. Fold Classification (SCOP + CATH) 12 domains

SCOP 2.08 (8 domains)

CATH v4.4 (4 domains)

7. Citations (4)