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1azm

DRUG-PROTEIN INTERACTIONS: STRUCTURE OF SULFONAMIDE DRUG COMPLEXED WITH HUMAN CARBONIC ANHYDRASE I

Method: X-RAY DIFFRACTION Dmax: 60.2 Å Quality: GOOD

SAXS Profile

SAXS profile for 1azm

P(r) Distribution

P(r) distribution for 1azm

1. Structure Basics

entry_id1azm
deposition_date1993-11-28
titleDRUG-PROTEIN INTERACTIONS: STRUCTURE OF SULFONAMIDE DRUG COMPLEXED WITH HUMAN CARBONIC ANHYDRASE I
keywordsPROTEIN-DRUG INTERACTIONS, OXO-ACID LYASE, SULFONAMIDES, LYASE(OXO-ACID); LYASE(OXO-ACID)
methodX-RAY DIFFRACTION

Download Data

2. SAXS Parameters (CRYSOL)

rg_guinier18.54
rg_electron17.37
i015259700.00
molecular_weight28808.0 kDa
excluded_volume35728 ų
envelope_volume40903 ų
shell_volume19154 ų
envelope_diameter60.9
shell_rg24.05
envelope_rg17.68
shape_rg17.34
total_rg18.39
total_atoms2033
n_residues258
n_harmonics20
q_range— – 0.5000 −1
n_points101
shell_typedirectional
solvent_density0.3340 e/ų
contrast_shell0.0300 e/ų
crysol_version4.1.3

3. P(r) Analysis (GNOM)

dmax60.2
rg_real18.40
rg_real_error0.28
i0_real1.5260e+07
i0_real_error1.8130e+05
rg_reciprocal18.42
i0_reciprocal15260000.0000
total_estimate0.8789
solution_quality GOOD a GOOD solution
n_peaks2
r_peak_primary23.9
skewness0.088
kurtosis-0.429
angular_range— – 0.4300 −1
current_alpha0.0000
highest_alpha3012000.0000
n_real_points74
gnom_version4.1.3
quality_criteria AN1: 0.000; Oscil: 0.823; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.991; Smooth: 0.961

4. Crystallography & Experiment

5. Entities & Polymer Info (4)

6. Citations (3)

7. Files & Curves (10)