SAXSdb — 1c1g

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1. Protein Identity and Related Structures Protein Identity & Related Structures

TROPOMYOSIN

OrganismNot specified

State in the Current Structure

Assembly	Oligomeric State	Construct	Mutations and Modifications	Ligands, Ions and Associated Components	Method and Experimental Conditions	Structure Quality
1	Protein homooligomer Homooligomer Protein × 2 PDB declaration: dimeric（2） Consistent with protein copy count	Chain A； UniProt 1–284 Chain B； UniProt 1–284	Not recorded	No other associated polymer	X-RAY DIFFRACTION X-ray crystallization conditions：LIQUID DIFFUSION；pH 7.4；291 K；SPERMINE, pH 7.4, LIQUID DIFFUSION, temperature 18K	Resolution 7.00 Å
2	Protein homooligomer Homooligomer Protein × 2 PDB declaration: dimeric（2） Consistent with protein copy count	Chain C； UniProt 1–284 Chain D； UniProt 1–284	Not recorded	No other associated polymer	X-RAY DIFFRACTION X-ray crystallization conditions：LIQUID DIFFUSION；pH 7.4；291 K；SPERMINE, pH 7.4, LIQUID DIFFUSION, temperature 18K	Resolution 7.00 Å

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

Other PDB	Difference from Current Entry 1C1G	Assembly / Oligomeric State	Construct	Mutations and Modifications	Ligands, Ions and Non-polymers	Method and Experimental Conditions	Structure Quality
8DD0 The structure of the native cardiac thin filament junction region Deposited 2022-06-17	Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics	Assembly 1 Protein heterocomplex Heteromer；Protein × 16 PDB declaration: hexadecameric	Chain G 1–284（284 aa） Chain H 1–284（284 aa） Chain I 1–284（284 aa） Chain J 1–284（284 aa） Chain L 1–284（284 aa） Chain M 1–284（284 aa） Chain N 1–284（284 aa） Chain O 1–284（284 aa）	Not recorded	ADP ADENOSINE-5'-DIPHOSPHATE × 6 MG MAGNESIUM ION × 6	ELECTRON MICROSCOPY cryo-EM buffer pH 7 cryo-EM vitrification conditions Cryogen ETHANE	Resolution 3.50 Å
8UWW The structure of the native cardiac thin filament troponin core in Ca2+-free state from the upper strand Deposited 2023-11-08	Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics	Assembly 1 Protein heterocomplex Heteromer；Protein × 7 PDB declaration: heptameric	Chain F 1–284（284 aa） Chain G 1–284（284 aa）	Not recorded	No recorded non-water small molecule	ELECTRON MICROSCOPY cryo-EM buffer pH 7 cryo-EM vitrification conditions Cryogen ETHANE	Resolution 5.10 Å
8UWX The structure of the native cardiac thin filament troponin core in Ca2+-free tilted state from the upper strand Deposited 2023-11-08	Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics	Assembly 1 Protein heterocomplex Heteromer；Protein × 7 PDB declaration: heptameric	Chain F 1–284（284 aa） Chain G 1–284（284 aa）	Not recorded	No recorded non-water small molecule	ELECTRON MICROSCOPY cryo-EM buffer pH 7 cryo-EM vitrification conditions Cryogen ETHANE	Resolution 6.00 Å
8UWY The structure of the native cardiac thin filament troponin core in Ca2+-free rotated state from the upper strand Deposited 2023-11-08	Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics	Assembly 1 Protein heterocomplex Heteromer；Protein × 7 PDB declaration: heptameric	Chain F 1–284（284 aa） Chain G 1–284（284 aa）	Not recorded	No recorded non-water small molecule	ELECTRON MICROSCOPY cryo-EM buffer pH 7 cryo-EM vitrification conditions Cryogen ETHANE	Resolution 5.50 Å
8UYD The structure of the native cardiac thin filament troponin core in Ca2+-free state from the lower strand Deposited 2023-11-13	Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics	Assembly 1 Protein heterocomplex Heteromer；Protein × 7 PDB declaration: heptameric	Chain F 1–284（284 aa） Chain G 1–284（284 aa）	Not recorded	ADP ADENOSINE-5'-DIPHOSPHATE × 2 MG MAGNESIUM ION × 2	ELECTRON MICROSCOPY cryo-EM buffer pH 7 cryo-EM vitrification conditions Cryogen ETHANE	Resolution 5.30 Å
8UZ5 The structure of the native cardiac thin filament troponin core in Ca2+-free rotated state from the lower strand Deposited 2023-11-14	Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics	Assembly 1 Protein heterocomplex Heteromer；Protein × 7 PDB declaration: heptameric	Chain F 1–284（284 aa） Chain G 1–284（284 aa）	Not recorded	ADP ADENOSINE-5'-DIPHOSPHATE × 2 MG MAGNESIUM ION × 2	ELECTRON MICROSCOPY cryo-EM buffer pH 7 cryo-EM vitrification conditions Cryogen ETHANE	Resolution 5.90 Å
8UZ6 The structure of the native cardiac thin filament troponin core in Ca2+-free tilted state from the lower strand Deposited 2023-11-14	Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics	Assembly 1 Protein heterocomplex Heteromer；Protein × 7 PDB declaration: heptameric	Chain F 1–284（284 aa） Chain G 1–284（284 aa）	Not recorded	ADP ADENOSINE-5'-DIPHOSPHATE × 2 MG MAGNESIUM ION × 2	ELECTRON MICROSCOPY cryo-EM buffer pH 7 cryo-EM vitrification conditions Cryogen ETHANE	Resolution 7.10 Å
8UZX The structure of the native cardiac thin filament troponin core in Ca2+-bound fully activated state from the upper strand Deposited 2023-11-16	Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics	Assembly 1 Protein heterocomplex Heteromer；Protein × 7 PDB declaration: heptameric	Chain F 1–284（284 aa） Chain G 1–284（284 aa）	Not recorded	ADP ADENOSINE-5'-DIPHOSPHATE × 2 MG MAGNESIUM ION × 2 CA CALCIUM ION × 3	ELECTRON MICROSCOPY cryo-EM buffer pH 7.2 cryo-EM vitrification conditions Cryogen ETHANE	Resolution 5.40 Å
8UZY The structure of the native cardiac thin filament troponin core in Ca2+-bound partially activated state from the upper strand Deposited 2023-11-16	Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics	Assembly 1 Protein heterocomplex Heteromer；Protein × 7 PDB declaration: heptameric	Chain F 1–284（284 aa） Chain G 1–284（284 aa）	Not recorded	ADP ADENOSINE-5'-DIPHOSPHATE × 2 MG MAGNESIUM ION × 2 CA CALCIUM ION × 3	ELECTRON MICROSCOPY cryo-EM buffer pH 7.2 cryo-EM vitrification conditions Cryogen ETHANE	Resolution 5.30 Å
8V01 The structure of the native cardiac thin filament troponin core in Ca2+-bound fully activated state 1 from the lower strand Deposited 2023-11-16	Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics	Assembly 1 Protein heterocomplex Heteromer；Protein × 7 PDB declaration: heptameric	Chain F 1–284（284 aa） Chain G 1–284（284 aa）	Not recorded	ADP ADENOSINE-5'-DIPHOSPHATE × 2 MG MAGNESIUM ION × 2 CA CALCIUM ION × 3	ELECTRON MICROSCOPY cryo-EM buffer pH 7.2 cryo-EM vitrification conditions Cryogen ETHANE	Resolution 5.50 Å
8V0I The structure of the native cardiac thin filament troponin core in Ca2+-bound fully activated state 2 from the lower strand Deposited 2023-11-17	Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics	Assembly 1 Protein heterocomplex Heteromer；Protein × 7 PDB declaration: heptameric	Chain F 1–284（284 aa） Chain G 1–284（284 aa）	Not recorded	ADP ADENOSINE-5'-DIPHOSPHATE × 2 MG MAGNESIUM ION × 2 CA CALCIUM ION × 3	ELECTRON MICROSCOPY cryo-EM buffer pH 7.2 cryo-EM vitrification conditions Cryogen ETHANE	Resolution 5.80 Å
8V0K The structure of the native cardiac thin filament troponin core in Ca2+-bound partially activated state from the lower strand Deposited 2023-11-17	Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics	Assembly 1 Protein heterocomplex Heteromer；Protein × 7 PDB declaration: heptameric	Chain F 1–284（284 aa） Chain G 1–284（284 aa）	Not recorded	ADP ADENOSINE-5'-DIPHOSPHATE × 2 MG MAGNESIUM ION × 2 CA CALCIUM ION × 3	ELECTRON MICROSCOPY cryo-EM buffer pH 7.2 cryo-EM vitrification conditions Cryogen ETHANE	Resolution 5.20 Å
8V0Y The structure of the native cardiac thin filament troponin core in Ca2+-free state from the upper strand activated by the C1-domain of cardiac myosin binding protein C Deposited 2023-11-17	Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions	Assembly 1 Protein heterocomplex Heteromer；Protein × 7 PDB declaration: heptameric	Chain F 1–284（284 aa） Chain G 1–284（284 aa）	Not recorded	ADP ADENOSINE-5'-DIPHOSPHATE × 2 MG MAGNESIUM ION × 2	ELECTRON MICROSCOPY cryo-EM buffer pH 7 cryo-EM vitrification conditions Cryogen ETHANE	Resolution 7.00 Å

13 other PDB entries and 13 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence

UniProt name	TPM1_PIG
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain A； PDBConstruct 1–284； UniProt 1–284 Author chain B； PDBConstruct 1–284； UniProt 1–284 Author chain C； PDBConstruct 1–284； UniProt 1–284 Author chain D； PDBConstruct 1–284； UniProt 1–284

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	1c1g
Deposition date deposition_date	1999-07-22
Structure title title	CRYSTAL STRUCTURE OF TROPOMYOSIN AT 7 ANGSTROMS RESOLUTION IN THE SPERMINE-INDUCED CRYSTAL FORM
Keywords keywords	TROPOMYOSIN COILED-COIL ALPHA-HELICAL, CONTRACTILE PROTEIN; CONTRACTILE PROTEIN
Experimental Method method	X-RAY DIFFRACTION

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3. SAXS Parameters (CRYSOL theoretical calculation) 3. SAXS Parameters (CRYSOL)

Radius of gyration Rg (Guinier) rg_guinier	— Å
Radius of gyration Rg (electron density) rg_electron	134.60 Å
Forward intensity I(0) i0	264136000.00
Molecular weight molecular_weight	130810.0 kDa
Excluded volume excluded_volume	161950 Å³
Envelope volume envelope_volume	339530 Å³
Hydration-shell volume shell_volume	32495 Å³
Envelope diameter envelope_diameter	528.7 Å
Shell Rg shell_rg	49.32 Å
Envelope Rg envelope_rg	141.60 Å
Shape Rg shape_rg	134.20 Å
Total Rg total_rg	134.30 Å
Total atoms total_atoms	9160
Residues n_residues	1136
Spherical-harmonic order n_harmonics	20
q range q_range	— – 0.5000 Å⁻¹
Data points n_points	101
Shell type shell_type	directional
Solvent electron density solvent_density	0.3340 e/Å³
Shell contrast contrast_shell	0.0300 e/Å³
CRYSOL version crysol_version	4.1.3

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4. P(r) Distance Distribution (GNOM inversion) 4. P(r) Analysis (GNOM)

Maximum dimension Dmax dmax	267.8 Å
Rg (real space) rg_real	92.38 Å
Rg uncertainty (real space) rg_real_error	1.22 Å
I(0) (real space) i0_real	2.1970e+08
I(0) uncertainty (real space) i0_real_error	4.8380e+06
Rg (reciprocal space) rg_reciprocal	93.51 Å
I(0) (reciprocal space) i0_reciprocal	239400000.0000
Solution quality estimate total_estimate	0.6720
Solution quality rating solution_quality	REASONABLE a REASONABLE solution
P(r) peaks n_peaks	2
Primary peak position r_peak_primary	48.7 Å
Skewness Skewness skewness	0.296
Kurtosis Kurtosis kurtosis	-1.061
Angular range angular_range	— – 0.0550 Å⁻¹
Current regularization parameter α current_alpha	3.3430
Highest regularization parameter α highest_alpha	35790000.0000
Real-space data points n_real_points	12
GNOM version gnom_version	4.1.3
Quality Criteria quality_criteria	AN1: 0.206; Oscil: 0.536; Stabil: 0.787; Sysdev: 1.000; Positv: 1.000; Valcen: 0.767; Smooth: 0.000

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5. Crystallography and Experiment 5. Crystallography & Experiment

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6. Entities and Polymers Entities & Polymers (1)

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7. Fold Classification (SCOP + CATH) 4 domains

SCOP 2.08 (4 domains)

Domain ID domain_id	d1c1ga_
Class class	h — Coiled coil proteins
Fold Fold fold	h.1 — Parallel coiled-coil
Superfamily Superfamily superfamily	h.1.5 — Tropomyosin
Family Family family	h.1.5.1 — Tropomyosin

Domain ID domain_id	d1c1gb_
Class class	h — Coiled coil proteins
Fold Fold fold	h.1 — Parallel coiled-coil
Superfamily Superfamily superfamily	h.1.5 — Tropomyosin
Family Family family	h.1.5.1 — Tropomyosin

Domain ID domain_id	d1c1gc_
Class class	h — Coiled coil proteins
Fold Fold fold	h.1 — Parallel coiled-coil
Superfamily Superfamily superfamily	h.1.5 — Tropomyosin
Family Family family	h.1.5.1 — Tropomyosin

Domain ID domain_id	d1c1gd_
Class class	h — Coiled coil proteins
Fold Fold fold	h.1 — Parallel coiled-coil
Superfamily Superfamily superfamily	h.1.5 — Tropomyosin
Family Family family	h.1.5.1 — Tropomyosin

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8. Citations (1)

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Unit-cell length a length_a	259.738 Å
Unit-cell length b length_b	55.300 Å
Unit-cell length c length_c	136.259 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	97.42 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	16

Space group space_group	C 1 2 1
Space-group number int_tables_number	5
Crystal system crystal_system	—

Resolution resolution	7.000 Å
Low-resolution limit resolution_low	100.000 Å
R factor r_factor	—
R_work r_work	0.4040
R_free r_free	—

Description description	TROPOMYOSIN
Molecular weight formula_weight	32784.6 kDa
Source method src_method	nat
Copy count entity_count	4

Polymer type type	polypeptide(L)
Chain IDs strand_id	A,B,C,D
Atom count atom_count	9160

CRYSTAL STRUCTURE OF TROPOMYOSIN AT 7 ANGSTROMS RESOLUTION IN THE SPERMINE-INDUCED CRYSTAL FORM

1. Protein Identity and Related Structures Protein Identity & Related Structures

TROPOMYOSIN

State in the Current Structure

Other States of the Same Protein in the Database

SAXS scattering curve SAXS Profile

P(r) Distance Distribution P(r) Distribution

2. Structure Basics 2. Structure Basics

3. SAXS Parameters (CRYSOL theoretical calculation) 3. SAXS Parameters (CRYSOL)

4. P(r) Distance Distribution (GNOM inversion) 4. P(r) Analysis (GNOM)

5. Crystallography and Experiment 5. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

6. Entities and Polymers Entities & Polymers (1)

Entity 1 Entity 1 polymer

Polymer Polymer

7. Fold Classification (SCOP + CATH) 4 domains

SCOP 2.08 (4 domains)

8. Citations (1)

9. Files and Curves (10)

Files (7)

Curves (3)

fit	/app/data/saxs_computation/c1/1c1g/1c1g.fit
pddf	/app/data/pr_computation/c1/1c1g/1c1g.pr.out
profile	/app/data/saxs_computation/c1/1c1g/1c1g.dat