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1c6z

;ALTERNATE BINDING SITE FOR THE P1-P3 GROUP OF A CLASS OF POTENT HIV-1 PROTEASE INHIBITORS AS A RESULT OF CONCERTED STRUCTURAL CHANGE IN 80'S LOOP. ;

Method: X-RAY DIFFRACTION Dmax: 65.0 Å Quality: GOOD

SAXS Profile

SAXS profile for 1c6z

P(r) Distribution

P(r) distribution for 1c6z

1. Structure Basics

entry_id1c6z
deposition_date1999-12-28
title;ALTERNATE BINDING SITE FOR THE P1-P3 GROUP OF A CLASS OF POTENT HIV-1 PROTEASE INHIBITORS AS A RESULT OF CONCERTED STRUCTURAL CHANGE IN 80'S LOOP. ;
keywordshydrolase-hydrolase inhibitor complex; HYDROLASE/HYDROLASE INHIBITOR
methodX-RAY DIFFRACTION

Download Data

2. SAXS Parameters (CRYSOL)

rg_guinier18.25
rg_electron17.31
i07977000.00
molecular_weight22220.0 kDa
excluded_volume28494 ų
envelope_volume32025 ų
shell_volume15906 ų
envelope_diameter62.1
shell_rg22.90
envelope_rg17.56
shape_rg17.31
total_rg18.26
total_atoms1563
n_residues198
n_harmonics20
q_range— – 0.5000 −1
n_points101
shell_typedirectional
solvent_density0.3340 e/ų
contrast_shell0.0300 e/ų
crysol_version4.1.3

3. P(r) Analysis (GNOM)

dmax65.0
rg_real18.23
rg_real_error0.45
i0_real7.9770e+06
i0_real_error1.0600e+05
rg_reciprocal18.23
i0_reciprocal7977000.0000
total_estimate0.7585
solution_quality GOOD a GOOD solution
n_peaks2
r_peak_primary59.7
skewness0.354
kurtosis-0.236
angular_range— – 0.4350 −1
current_alpha0.0000
highest_alpha3268000.0000
n_real_points75
gnom_version4.1.3
quality_criteria AN1: 0.000; Oscil: 0.639; Stabil: 0.989; Sysdev: 1.000; Positv: 1.000; Valcen: 0.971; Smooth: 0.000

4. Crystallography & Experiment

5. Entities & Polymer Info (3)

6. Citations (2)

7. Files & Curves (10)