CRYSTAL STRUCTURE OF THE RNA-DEPENDENT RNA POLYMERASE OF HEPATITIS C VIRUS

Method: X-RAY DIFFRACTION D_max: 103.7 Å Quality: EXCELLENT

SAXS Profile

P(r) Distribution

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1. Structure Basics

entry_id	1csj
deposition_date	1999-08-18
title	CRYSTAL STRUCTURE OF THE RNA-DEPENDENT RNA POLYMERASE OF HEPATITIS C VIRUS
keywords	;POLYPROTEIN, GLYCOPROTEIN, RNA-DIRECTED RNA POLYMERASE, CORE PROTEIN, COAT PROTEIN, ENVELOPE PROTEIN, HELICASE, ATP-BINDING, TRANSMEMBRANE, NONSTRUCTURAL PROTEIN, TRANSFERASE ;; TRANSFERASE
method	X-RAY DIFFRACTION

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Download Data

SAXS curve (.dat) P(r) distribution (.pr.out) Structure (CIF)

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2. SAXS Parameters (CRYSOL)

rg_guinier	33.45 Å
rg_electron	32.65 Å
i0	229855000.00
molecular_weight	118790.0 kDa
excluded_volume	147290 Å³
envelope_volume	184950 Å³
shell_volume	46815 Å³
envelope_diameter	106.4 Å
shell_rg	40.18 Å
envelope_rg	32.12 Å
shape_rg	32.65 Å
total_rg	33.20 Å
total_atoms	8244
n_residues	1038
n_harmonics	20
q_range	— – 0.5000 Å⁻¹
n_points	101
shell_type	directional
solvent_density	0.3340 e/Å³
contrast_shell	0.0300 e/Å³
crysol_version	4.1.3

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3. P(r) Analysis (GNOM)

dmax	103.7 Å
rg_real	33.36 Å
rg_real_error	0.84 Å
i0_real	2.2990e+08
i0_real_error	3.6950e+06
rg_reciprocal	33.42 Å
i0_reciprocal	229900000.0000
total_estimate	0.9057
solution_quality	EXCELLENT a EXCELLENT solution
n_peaks	1
r_peak_primary	39.7 Å
skewness	0.212
kurtosis	-0.564
angular_range	— – 0.2350 Å⁻¹
current_alpha	0.0000
highest_alpha	24120000.0000
n_real_points	48
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.949; Stabil: 0.999; Sysdev: 1.000; Positv: 1.000; Valcen: 1.000; Smooth: 0.926

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4. Crystallography & Experiment

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5. Entities & Polymer Info (2)

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6. Citations (1)

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length_a	67.063 Å
length_b	96.895 Å
length_c	194.432 Å
angle_alpha	90.00 °
angle_beta	90.00 °
angle_gamma	90.00 °
z_pdb	8

space_group	P 21 21 21
int_tables_number	19
crystal_system	—

resolution	2.800 Å
resolution_low	19.000 Å
r_factor	—
r_work	0.2370
r_free	0.2860

description	HEPATITIS C VIRUS RNA POLYMERASE (NS5B)
formula_weight	59446.2 kDa
ec_number	2.7.7.48
src_method	man
entity_count	2

type	polypeptide(L)
strand_id	A,B
atom_count	8428

CRYSTAL STRUCTURE OF THE RNA-DEPENDENT RNA POLYMERASE OF HEPATITIS C VIRUS

SAXS Profile

P(r) Distribution

1. Structure Basics

Download Data

2. SAXS Parameters (CRYSOL)

3. P(r) Analysis (GNOM)

4. Crystallography & Experiment

Unit Cell

Symmetry

Refinement

Diffraction

5. Entities & Polymer Info (2)

Entity 1 polymer

Polymer

Source

Entity 2 water

6. Citations (1)

7. Files & Curves (10)

Files (7)

Curves (3)

organism	Hepatitis C virus
ncbi_taxonomy_id	11103
host_organism	Escherichia coli

description	water
formula_weight	18.0 kDa
src_method	nat
entity_count	184

fit	/app/data/saxs_computation/cs/1csj/1csj.fit
pddf	/app/data/pr_computation/cs/1csj/1csj.pr.out
profile	/app/data/saxs_computation/cs/1csj/1csj.dat