1dsm
(-)-duocarmycin SA covalently linked to duplex DNA
SAXS Profile
P(r) Distribution
1. Structure Basics
| entry_id | 1dsm |
| deposition_date | 1999-03-27 |
| title | (-)-duocarmycin SA covalently linked to duplex DNA |
| keywords | DUOCARMYCIN, DNA, MINOR GROOVE BINDING, ANTITUMOR AGENT, DRUG-DNA COMPLEX; DNA |
| method | SOLUTION NMR |
Download Data
2. SAXS Parameters (CRYSOL)
| rg_guinier | 11.87 Å |
| rg_electron | 11.77 Å |
| i0 | 731250000.00 |
| molecular_weight | 143380.0 kDa |
| excluded_volume | 143070 ų |
| envelope_volume | 10143 ų |
| shell_volume | 7640 ų |
| envelope_diameter | 40.9 Å |
| shell_rg | 16.86 Å |
| envelope_rg | 12.48 Å |
| shape_rg | 11.61 Å |
| total_rg | 12.09 Å |
| total_atoms | 15140 |
| n_residues | 440 |
| n_harmonics | 20 |
| q_range | — – 0.5000 Å−1 |
| n_points | 101 |
| shell_type | directional |
| solvent_density | 0.3340 e/ų |
| contrast_shell | 0.0300 e/ų |
| crysol_version | 4.1.3 |
3. P(r) Analysis (GNOM)
| dmax | 33.8 Å |
| rg_real | 11.88 Å |
| rg_real_error | 0.21 Å |
| i0_real | 7.3130e+08 |
| i0_real_error | 7.1580e+06 |
| rg_reciprocal | 11.88 Å |
| i0_reciprocal | 731300000.0000 |
| total_estimate | 0.8384 |
| solution_quality | GOOD a GOOD solution |
| n_peaks | 1 |
| r_peak_primary | 11.1 Å |
| skewness | 0.282 |
| kurtosis | -0.590 |
| angular_range | — – 0.5000 Å−1 |
| current_alpha | 0.0000 |
| highest_alpha | 105000.0000 |
| n_real_points | 80 |
| gnom_version | 4.1.3 |
| quality_criteria | AN1: 0.000; Oscil: 0.976; Stabil: 0.995; Sysdev: 1.000; Positv: 1.000; Valcen: 0.981; Smooth: 0.000 |