;Nonpeptidic inhibitors of human leukocyte elastase. 5. Design, synthesis, and X-ray crystallography of a series of orally active 5-aminopyrimidin-6-one-containing trifluoromethyl ketones.
;
J.Med.Chem. (1995)
;Nonpeptidic Inhibitors of Human Leukocyte Elastase. 3. Design, Synthesis, X-Ray Crystallographic Analysis, and Structure-Activity Relationships for a Series of Orally Active 3-Amino-6-Phenylpyridin-2-One Trifluoromethyl Ketones
;
J.Med.Chem. (1994)
;Nonpeptidic Inhibitors of Human Leukocyte Elastase. 2. Design, Synthesis and in Vitro Activity of a Series of 3-Amino-6-Arylpyridin-2-One Trifluoromethyl Ketones
;
J.Med.Chem. (1994)
Nonpeptidic Inhibitors of Human Leukocyte Elastase. 1. The Design and Synthesis of Pyridone-Containing Inhibitors
J.Med.Chem. (1994)
Design of Orally Active, Nonpeptidic Inhibitors of Human Leukocyte Elastase
J.Med.Chem. (1994)
;Design, Synthesis, and Kinetic Evaluation of a Unique Class of Elastase Inhibitors, the Peptidyl Alpha-Ketobenzoxazoles,and the X-Ray Crystal Structure of the Covalent Complex between Porcine Pancreatic Elastase and Ac-Ala-Pro-Val-2-Benzoxazole
;
J.Am.Chem.Soc. (1992)
;Crystal Structure of the Covalent Complex Formed by a Peptidyl Alpha,Alpha-Difluoro-Beta-Keto Amide with Porcine Pancreatic Elastase at 1.78-Angstrom Resolution
;
J.Am.Chem.Soc. (1989)
X-Ray Diffraction Analysis of the Inhibition of Porcine Pancreatic Elastase by a Peptidyl Trifluoromethylketone
J.Mol.Biol. (1988)
;Nonpeptidic Inhibitors of Human Leukocyte Elastase. 6. Design of a Potent, Intratracheally Active, Pyridone-Based Trifluoromethyl Ketone
;
To be Published
;Nonpeptidic Inhibitors of Human Leukocyte Elastase. 4. Design, Synthesis,in Vitro, and in Vivo Activity of a Series of Beta-Carbolinone-Containing Trifluoromethyl Ketones
;
To be Published
