8etj

Fkbp39 associated 60S nascent ribosome State 2

Method: ELECTRON MICROSCOPY D_max: 262.6 Å Quality: GOOD

SAXS 散射曲线 SAXS Profile

P(r) 距离分布 P(r) Distribution

下载 Download SAXS (.dat) P(r) (.pr.out) CIF

▼

1. 结构基本信息 1. Structure Basics

条目编号 entry_id	8etj
沉积日期 deposition_date	2022-10-17
结构标题 title	Fkbp39 associated 60S nascent ribosome State 2
关键词 keywords	60S Ribosome, nucleophosmin, ribosome biogenesis, fkbp, ribosome; RIBOSOME
实验方法 method	ELECTRON MICROSCOPY

▼

2. SAXS 参数 (CRYSOL 理论计算) 2. SAXS Parameters (CRYSOL)

回转半径 Rg (Guinier) rg_guinier	73.51 Å
回转半径 Rg (电子) rg_electron	74.80 Å
零角强度 I(0) i0	38249000000.00
分子量 molecular_weight	1173200.0 kDa
排除体积 excluded_volume	1265300 Å³
包络体积 envelope_volume	2136400 Å³
水化壳体积 shell_volume	225390 Å³
包络直径 envelope_diameter	254.3 Å
壳层 Rg shell_rg	82.35 Å
包络 Rg envelope_rg	73.57 Å
形状 Rg shape_rg	74.91 Å
总 Rg total_rg	74.62 Å
总原子数 total_atoms	79836
残基数 n_residues	6940
球谐函数阶数 n_harmonics	20
q 范围 q_range	— – 0.5000 Å⁻¹
数据点数 n_points	101
壳层类型 shell_type	directional
溶剂电子密度 solvent_density	0.3340 e/Å³
壳层衬度 contrast_shell	0.0300 e/Å³
CRYSOL 版本 crysol_version	4.1.3

▼

3. P(r) 距离分布 (GNOM 反演) 3. P(r) Analysis (GNOM)

最大尺寸 Dmax dmax	262.6 Å
Rg (实空间) rg_real	76.74 Å
Rg 误差 (实空间) rg_real_error	1.48 Å
I(0) (实空间) i0_real	3.8310e+10
I(0) 误差 (实空间) i0_real_error	7.5010e+08
Rg (倒空间) rg_reciprocal	73.72 Å
I(0) (倒空间) i0_reciprocal	38270000000.0000
解质量估计 total_estimate	0.8979
解质量评级 solution_quality	GOOD a GOOD solution
P(r) 峰数 n_peaks	1
主峰位置 r_peak_primary	87.5 Å
偏度 Skewness skewness	0.483
峰度 Kurtosis kurtosis	-0.033
角度范围 angular_range	— – 0.1050 Å⁻¹
当前正则化参数 α current_alpha	1.0840
最高正则化参数 α highest_alpha	4854000000.0000
实空间数据点数 n_real_points	22
GNOM 版本 gnom_version	4.1.3
质量判据 quality_criteria	AN1: 0.000; Oscil: 0.817; Stabil: 0.878; Sysdev: 1.000; Positv: 1.000; Valcen: 0.972; Smooth: 0.643

▶

4. 晶体学与实验 4. Crystallography & Experiment

▶

5. 实体与聚合体信息 (36)

Entity 1 polymer

描述 description	RNA (1758-MER)
分子量 formula_weight	1129508.0 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polyribonucleotide
链编号 strand_id	1
原子数 atom_count	79857

AUUUGACCUCAAAUCAGGUAGGACUACGCGCUGAACUUAAGCAUAUCAAUAAGCGCAGGAAAAGAAAAUAACCAUGAUUCCCUCAGUAACGGCGAGUGAAGCGGGAAAAGCUCAAAUUUGAAAUCUGGCAACAUUUCUUUUGUUGUCCGAGUUGUAAUUUCAAGAAGCUGCUUUGAGUGUAGACGAUCGGUCUAAGUUCCUUGGAACAGGACGUCAGAGAGGGUGAGAACCCCGUCUUUGGUCGAUUGGAUAUGCCAUAUAAAGCGCUUUCGAAGAGUCGAGUUGUUUGGGAAUGCAGCUCUAAAUGGGUGGUAAAUUUCAUCUAAAGCUAAAUAUUGGCGAGAGACCGAUAGCGAACAAGUAGAGUGAUCGAAAGAUGAAAAGAACUUUGAAAAGAGAGUUAAAUAGUACGUGAAAUUGCUGAAAGGGAAGCAUUGGAAAUCAGUCUUACCUGGGUGAGAUCAGUAGUCUCUUCGCGAGACUAUGCACUCUGAACCUGUGGUAGGUCAGCAUCAGUUUUCGGGGGCGGAAAAAGAAUAAGGGAAGGUGGCUUUCCGGGUUCUGCCUGGGGAGUGUUUAUAGCCCUUGUUGUAAUACGUCCACUGGGGACUGAGGACUGCGGCUUCGUGCCAAGGAUGCUGACAUAAUGGUUUUCAAUGGCCCGUCUUGAAACACGGACCAAGGAGUCUAGCAUCUAUGCGAGUGUUUGGGUGAUGAAAACCCAUCCGCGAAAUGAAAGUGAAUGCAGGUGGGAACGCCCUUGUGGCGUGCACCAUCGACCGACCCGGAAGUUUGUCAAUGGAAGGGUUUGAGUAAGAGCAUAGCUGUUGGGACCCGAAAGAUGGUGAACUAUGCCUGAAUAGGGUGAAGCCAGAGGAAACUCUGGUGGAGGCUCGUAGAGAUUCUGACGUGCAAAUCGAUCUUCAAAUUUGGGUAUAGGGGCGAAAGACUAAUCGAACCAUCUAGUAGCUGGUUCCUGCCGAAGUUUCCCUCAGGAUAGCAGAAACUCAGAUCAGUUUUAUGAGGUAAAGCGAAUGAUUAGAGGUCUUGGGGAAGGAAUUUCCUCAACCUAUUCUCAAACUUUAAAUAUGUAAGACGCCCUUGUCGCUUAAUUGGACGUGGGCCAUCGAAUGAGAGUUUCUAGUGGGCCAUUUUUGGUAAGCAGAACUGGCGAUGCGGGAUGAACCGAACGUGAGGUUAAGGUGCCGGAAUGUACGCUCAUCAGACACCAGAAAAGGUGUUAGUUCAUCUAGACAGCAGGACGGUGGCCAUGGAAGUCGGAAUCCGCUAAGGAGUGUGUAACAACUCACCUGCCGAAUGAACUAGCCCUGAAAAUGGAUGGCGCUUAAGCGUACUACCCAUACCUCACCGUCUGGGUUAGCUUUGAGAAGCUCAGACGAGUAGGCAGGCGUGGAGGUUUGUGACGAAGCCUUGGGCGUGAGCCUGGGUCGAACAGCCUCUAGUGCAGAUCUUGGUGGAAGUAGCAAAUAUUCAAAUGAGAACUUUGAAGACUGAAGUGGGGAAAGGUUCCAUGUGAACAGCAGUUGGACAUGGGUUAGUCGAUCCUAAGAGAUAGGGAAGCUCCGUAUGAAAGUUGCACGAUUUUUCGUGCCUCCUAUCGAAAGGGAAUCCGGUUAAUAUUCCGGAACCAGAAGGUGGAAUCAACACGGCAACGUAAAUGAAGUUGGAGACGUCGGCGGGAGCCCUGGGAAGAGUUCUCUUUUCUUUUUAACAAACCAUUGAACUACCCUGAAAUCGGUUUAUCCGGAGCUAGGGUAUGGUGUUUGGAAGAGUUCAGCGCCUCAUGCUGAAUCCGGUGCGCUCUCGACGGCCCUUGAAAAUCCAACGGAAGAAUGGACCUUCGGGUCCUUGUUUUCACAUCUGGUCGUACUCAUAACCGCAGCAGGUCUCCAAGGUGAACAGCCUCUAGUUGAUAGAACAAUGUAGAUAAGGGAAGUCGGCAAAAUGGAUCCGUAACUUCGGGAUAAGGAUUGGCUCUAAGGGUUGGGUACGUUGGGCCUUGGAACCUGAACGGUUGCUGGACUGAGCGUGGACCGAUGUCUUUUCUCGCCUUUCGGGGUGAGAAGGGAUGUUGGACCUGCUUGGACCUUGGCGGCCGGGAAGUCCUUGGUCGGGCUUUUCUCCUUCUCGGGGAUUAUGCUCUUACUGGCGUACGUUUAACAACCAACUUAGAACUGGUACGGACAAGGGGAAUCUGACUGUCUAAUUAAAACAUAGCAUUGCGAUGGCCAGAAAGUGGUGUUGACGCAAUGUGAUUUCUGCCCAGUGCUCUGAAUGUCAAAGUGAAGAAAUUCAACCAAGCGCGGGUAAACGGCGGGAGUAACUAUGACUCUCUUAAGGUAGCCAAAUGCCUCGUCAUCUAACUAGUGACGCGCAUGAAUGGAUUAACGAGAUUCCCACUGUCCCUAUCUACUAUCUAGCGAAACCACAGCCUGGGGAACGGGCCAGGCAAAAUCAGCGGGGAAAGAAGACCCUGUUGAGCUUGACUCUAGUUUGACAUUGUGAAGAGACAUAGAGGGUGUAGGAUAAGUGGGAGUAUGUUUCGGCAUACGCCGGUGAAAUACCACUACCUUUAUCGUUUCUUUACUUAAUCAAUGAAGCGGAAUUGGGAUUUAUUUCCCAUAUUCUAGCGUUAAAGUUUCUUCGCGAACUGAUCCGCGUUGAUGACAUUGUCAGGUGGGGAGUUUGGCUGGGGCGGCACAUCUGUUAAAAGAUAACGCAGGUGUCCUAAGGGGGACUCAUCGAGAACAGAAAUCUCGAGUAGAAUAAAAGGGUAAAAGUCCCCUUGAUUUUGAUUUUCAGUGUGAAUACAAACCAUGAAAGUGUGGCCUAUCGAUCCUUUGUUCCCUCGAAAUUUGAGGACAGAGGUGCCAGAAAAGUUACCACAGGGAUAACUGGCUUGUGGCAGUCAAGCGUUCAUAGCGACAUUGCUUUUUGAUUCUUCGAUGUCGGCUCUUCCUAUCAUACCGAAGCAGAAUUCGGUAAGCGUUGGAUUGUUCACCCACUAAUAGGGAACGUGAGCUGGGUUUAGACCGUCGUGAGACAGGUUAGUUUUACCCUACUGAUGAAGUGUCGUCGCAAUGGUAAUUCAACUUAGUACGAGAGGAACCGUUGAUUCAGAUCAUUGGUAUUUGCGGCUGCCUGACAAGGCAAUGCCGCGGAGCUAUCAUCUGCUGGAUAACGGCUGAACGCCUCUAAGCCAGAAUCCGUGCCAGAAAGCGACGAUUUUUUGGUCCGCAUGAUUUAUAUGUAUAAAAAUAGAGGUAGGACUUGUUCCUACUCUCCUGUAUCGUAGAAGAUGGGCGAUGGUUGAUGAAACGGAAGUGUUUUAUUGACUUGUCCAUGAAAUUCCAUUGAAAUCUUGUGCGGAAUCGAAUCCAUUGCAUACGACUUUAAUGUGGAACGGGGUAUUGUAAGCAGUAGAGUAGCCUUGUUGUUACGAUCUGCUGAGAUUAAGCCUUUGUUCCCAAGAUUUG

Entity 2 polymer

描述 description	RNA (144-MER)
分子量 formula_weight	52880.2 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polyribonucleotide
链编号 strand_id	2

AUUAUUUAAAACUUUCAGCAACGGAUCUCUUGGCUCUCGCAUCGAUGAAGAACGCAGCGAAAUGCGAUACGUAAUGUGAAUUGCAGAAUUCCGUGAAUCAUCGAAUCUUUGAACGCACAUUGCGCCUUUGGGUUCUACCAAAGGCAUGCCUGUUUGAGUGUCAUU

Entity 3 polymer

描述 description	Protein mak16
分子量 formula_weight	35686.9 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	3

MQQDEVIWQVVGHEFCSYRIKGEAQNFCRNEYNVTGLCNRQSCPLANSRYATVREDNGKLYLYMKTIERAHFPSKLWQRIKLSKNYAKALEQIDQQLLYWPGRQIHRCKQRLTRLTQYLLKARRLALKHQPALIPIKPKQAHREASRERKALIAAKLEKNIEKELVKRLKSGVYGDQPLNVNEEIWNKVLAAREGLIDEGEEEEEREEAELEFVSDDEDEEEISDLEDWLGSDQSMETSESEEEESSESESDEDEDEDNKGKIRKRKTDDAKKSRKKRAPHIHIEYEQERENEKIPAVQHSW

Entity 4 polymer

描述 description	60S ribosomal protein L3-A
分子量 formula_weight	43889.8 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	B

MSHCKFEQPRHGSLGFLPRKRASRQRGKVKAFPKDDASKPVHLTAFLGYKAGMTHIVRDLDRPGSKMHKREILEAVTVIETPPMVVVGVVGYVETPRGLRSLTTVWAEHLSEEVKRRFYKNWFKSKKKAFTKYAKKYAESTQSINRELERIKKYCSVVRVLAHTQIRKTPLAQKKAHLMEIQVNGGSVADKVEWAREHFEKTVDIKSTFEQNEMIDVIGVTRGKGNEGTTARWGTKRLPRKTHRGLRKVACIGAWHPANVQWTVARAGNAGYMHRTQLNSKIYRIGAGDDAKNASTDFDATEKRITPMGGFVRYGVVENDFVMLNGATPGPVKRVLTLRKSLLTHTSRKALEPVSLKWIDTASKFGHGRFQTPAEAKQFLGTLKKDVA

Entity 5 polymer

描述 description	60S ribosomal protein L4-B
分子量 formula_weight	39982.3 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	C

MAAARPTVSIYNKDGSVSSETLALPFVFKAPIRPDLVRSVHTAVAKNKRQPYAVSEKAGHQTSAESWGTGRALARIPRVGGGGTHRSGQAAFGNMCRSGRMFAPTKTWRKWHVKVNQNEKRYAIASAVAASGVPSLLLARGHRIEEIPEVPLVVDDAVQSFQKTKEAVALLKEIKAYRDVIKVANSRKLRAGKGKLRNRRHVQRRGPLVVFNEDTGIVKAFRNIPGVEIVNVRRLNLLQLAPGGHLGRFVIWTKSAFGLLDSVFGSTTEVAQLKKNYFLPENIISNADVTRLINSDEIQSIVKAAGPSRVKRAHVQKKNPLKNKAVLSRLNPYAKAYKANVKINSEKTPKAAGEKFLSVLHEN

Entity 6 polymer

描述 description	60S ribosomal protein L6
分子量 formula_weight	21286.0 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	E

MSTVKVNGAKNGGERMVLPAGEAAAKYYPAYRENVPKKARKAVRPTKLRASLAPGTVCILLAGRFRGKRVVVLSQLEDTLVVTGPYKVNGVPIRRVNHRYVIATSAPKIDVSGVSVEKFTKAYFAKQKRSGPVKKDEAFFAENAPKNALPAERIADQKAVDAKLLPAIKAIPNMKEYLAASFALSNGDRPHLMKF

Entity 7 polymer

描述 description	60S ribosomal protein L7-B
分子量 formula_weight	28499.3 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	F

MVASSTVPSVASIFAPESLLKKTKAQKQSREQIVAAAAEKKSARQKKRELIAKRAEAYEAEYRAAEREQIELARKARAEGNYFVPHEPKLIFVVRIRGINNIPPKARKIMQLLRLLQINNGIFVKFNKAIKEMLQVVEPYVTYGIPNHKTVRELIYKRGFGKVNKQRIPLSDNAIIEAALGKYSILSVEDLIHEIYTVGPNFKQAANFLWPFKLSSPLGGWRERKFKHFIEGGDAGKRDEHINGLVQKML

Entity 8 polymer

描述 description	60S ribosomal protein L8
分子量 formula_weight	28659.8 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	G

MAPKSKKVAPSPFAQPKAAKTTKNPLFVSRPRSFGIGQDIQPKRDLSRFVKWPEYIRLQRRRKILNLRLKVPPAIAQFQKTLDKNTATQVFKLLNKYRPETAAEKKQRLVAEAEAVANGKSAQDVSKKPYNVKYGLNHVVALIEAKKAKLVLIASDVDPIELVVFLPALCKKMGVPYAIVKNKARLGTVIHQKTAAVLAVTEVREEDKNELASIVSAVDANFSAKYDESRRKWGGGIMGGKTQALLAKRAKAAAATVRL

Entity 9 polymer

描述 description	60S ribosomal protein L9-A
分子量 formula_weight	21545.0 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	H

MGRDIYKDETLTIPKGVTVDIKARNVTVTGPRGTLKQNLRHVDIEMKKQGNTIKFIVWHGSRKHNACIRSVYSIINNMIIGVTQGFRYKMRLVYAHFPININLTENGTVVEIRNFLGERITRVIKCLPGVTVSISSAVKDEIILEGNSLENVSQSAANIKQICNVRNKDIRKFLDGIYVSERGNIEELEE

Entity 10 polymer

描述 description	60S ribosomal protein L13
分子量 formula_weight	23578.1 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	L

MAIHVKGQLPNAHFHKDWQRYVKTWFNQPGRKLRRRQARQTKAAKIAPRPVEAIRPAVKPPTIRYNMKVRAGRGFTLEELKAAGVSRRVASTIGIPVDHRRRNRSEESLQRNVERIKVYLAHLIVFPRKAGQPKKGDATDVSGAEQTDVAAVLPITQEAVEEAKPITEEAKNFNAFSTLSNERAYARYAGARAAFQKKRAEEAEAKKK

Entity 11 polymer

描述 description	60S ribosomal protein L14
分子量 formula_weight	15241.1 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	M

MEGFKRYVEVGRVVLVTKGEYTGKLAVIVDIVDHKRALIDSPCSEFPRQVIRYGSVVLTHIVMKLPRGARSGIVAKKWKAQDVCNKWASSAWAKKLEAKKVRSQLNDFDRFAVMRLKKQRREQVNVAVAKALKA

Entity 12 polymer

描述 description	60S ribosomal protein L15-A
分子量 formula_weight	23862.6 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	N

MGAYKYLEELAKKKQSDVNLFLSRVRAWEYRQMNVIHRASRPSRPDKARRLGYKAKQGYVIYRIRVRRGGRKRPVPKGQTYGKPVHQGVNHLKYQRSARCTAEERVGRYCSNLRVLNSYWVNQDATYKFFEVILVDPSHKAIRRDPRINWIVNPVHKHRESRGLTSIGKKSRGIGKGHRFNNSPQHATWLRHNTLSLRRYR

Entity 13 polymer

描述 description	60S ribosomal protein L16-B
分子量 formula_weight	22215.3 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	O

MSEFQKVVVIDAKGHLLGRLASVVAKQLLGGQKVVVVRCEELNISGHFFRNKLKYLAYLRKACRYNPSRGAFHFRAPSRIFQKAVRGMLPHKTARGQAALEHLQAVEGIPPPFDKQKRVVVPAALRVLRLKPGRKYCTVGRLSSEVGWKYNDIVAKLEERRKVKSAAFYQAKLAKQKKIASAKEASPVNQKLSQFGY

Entity 14 polymer

描述 description	60S ribosomal protein L17-A
分子量 formula_weight	20854.1 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	P

MVRYSASPALETKCAKARGAYLRTHFKNSREVAFTINGMSLKKAFIFLDNVKEHKQAVPFRRFNGGVGRTAQGKEFGVTQARWPVKSVKFFYDLLKNAEANAEAKGLDMDKLIIKHVQVNAAPKQRRRTYRAHGRVTAYLSSPSHIEIIVAEEEEAVPKANDTVSRVSLKQGAKARNLAARKAITAA

Entity 15 polymer

描述 description	60S ribosomal protein L18-A
分子量 formula_weight	21240.9 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	Q

MGIDIERHHVKKSQRSKPASENVYLKLLVKLYRFLARRTDSRFNKAILKRLFQSKTNRPPISISKIAALTSRKSASSQNKTTVVVGTVTDDERMLTVPKLSIAALRFTKSARARILKAGGEVLTLDQLALRAPTGSNTVLVRGKKHAREAYRHFGFGPHKHKAPYVRSEGRKFERARGRRKSRAFKV

Entity 16 polymer

描述 description	60S ribosomal protein L19-A
分子量 formula_weight	22783.8 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	R

MANLRTQKRLAASVLKCGKRKVWMDPNEISEISNANSRQNVRKLIKDGLVIRKPNLMHSRFRIRKTHAAKRLGRHTGYGKRKGTAEARMPSAVVWMRRQRVLRRLLRKYRESGKIDKHLYHTLYLEAKGNTFKHKRALIEHIQRAKAEANRTKLIQEQQDARRARAKAARQRRAKAVEEKREQLYTAAEKIEE

Entity 17 polymer

描述 description	60S ribosomal protein L20-A
分子量 formula_weight	20642.3 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	S

MALKEYQVVGRKVPTEHEPVPKLFRMRLFAPNESVAKSRYWYFLKMINKVKKATGEIVAINEISEPKPLKAKVFGIWIRYDSRSGTHNMYKEFRDTTRVGAVEAMYADMAARHRARFRSIRILKVVEVEKKEDVRRNYVKQLLNPHLKFPLPHRRTGVVGLAGKKVFAPHRPSTFY

Entity 18 polymer

描述 description	60S ribosomal protein L23-A
分子量 formula_weight	14905.5 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	V

MSRGRGAASGTKYRMTLGLPVQAIMNCADNSGAKNLYIVSVFGTGARLNRLPAASCGDMVLATVKKGKPDLRKKIMPAIVVRQRKAWRRKDGVYLYFEDNAGVIVNPKGEMKGSAITGPVAKECADLWPRIASNAGTVV

Entity 19 polymer

描述 description	Ribosome assembly factor mrt4
分子量 formula_weight	26698.7 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	W

MPKSRRSKVLTLAQTEKKGHEGKAALFSGVQQSLDSFDYMWIFDVTNMRNTYLKRIRDDWKGSRIFMGKTKVMAKALGHTPEEEHAENVSKLTKLLHGAVGLLFTNSKPDEVIGYFESFVQNDFARAGAVAPFTHVIPAGPVYSRAGQIPVEDDILLTHTLEPQVRQLGMPTVLKNGVVTLLADFPLCTEGQQLDSRQTRLLKLFGITAAEFKVGLLGYYSKKGASVEFLQSAPGADEAME

Entity 20 polymer

描述 description	60S ribosomal protein L26
分子量 formula_weight	14375.9 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	Y

MKFSRDVTSSRRKQRKAHFGAPSSVRRVLMSAPLSKELREQYKIRSLPVRRDDQITVIRGSNKGREGKITSVYRKKFLLLIERVTREKANGASAPVGIDASKVVITKLHLDKDRKDLIVRKGGKVE

Entity 21 polymer

描述 description	60S ribosomal protein L28-A
分子量 formula_weight	16691.5 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	a

MPTHVSKTRKLRGHVSAGHGRIGKHRKHPGGRGKAGGLQHLRSHFDKYHPGYFGKVGMRRFHLMKNPLWRPTVNLDRLWTLLPNEARDKYLGKNTEVAPVINVLQSGYGKVLGKGRLPETPVIVQTRYVSRRAEEKIKQAGGVVELIA

Entity 22 polymer

描述 description	Probable nucleolar GTP-binding protein 1
分子量 formula_weight	72915.4 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	b

MATAVFKNITPIPDVNTFLDVVLSRTQRKTPTVIRSGFKISRIRGFYGRKVKFTQDTITEKLDSILQEFPKLNDIHPFHADLLNILYDRDHLKIALSQLSTAKHLVENVARDYIRLLKYGDSLYRCKQLKRAALGRMATIIKRQKSSLEFLEQVRQHLSRLPAIDPNTRTLLVCGYPNVGKSSFMNKVTRAQVDVQPYAFTTKSLFVGHFDYKYLRWQVIDTPGILDHPLEQMNTIEMQSITAMAHLRSAVLYFMDLSEMCGYSVAAQVKLYHSIKPLFANKVTILVLNKIDAMRPEDLDQKNQELLQTIIDDGNVKVVQTSCVQDIGVMDVRTTACEALLAARVEQKLKGSRVNNVLNRIHLAEPAARDEVARPACIPDSVKTRRAYDANDPNRRILARDIEAANGGAGVYNVELRDKYILQDPSWKYDRMPELLDGKNVADFVDPEIEAKLLALDEEEERLEREGYYDSDQEIEDADEEEVLEKASRIREKNKLTMLAARQKKIKNRPVLPRTAGIRTLDELQSSLQSAGLPSDSIEERARSRARTAAANEMADGSGVDLLMNEGEEIRSKSIAPRSQSNRRESGVHAEGARSYADRLARVKQIHRNRMARASESDRHVIAAKPKHLLSGKRGNGKTQRR

Entity 23 polymer

描述 description	60S ribosomal protein L31
分子量 formula_weight	13290.5 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	d

MANTKKSAINQVVTRDYTIHMHKRLYGVSFKKRAPRAIKEIVAFAQKHMQTKEVRVDPSLNKEVWKRGIRNVPHRLRLRLSRKRSDEDDKALYTYVQAVDVANPKMETTVVEE

Entity 24 polymer

描述 description	60S ribosomal protein L32-A
分子量 formula_weight	14491.1 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	e

MAAVNIIKKRTKPFKRHQSDRFKRVGESWRKPRGIDSCVRRRFRGTISMPKIGYGNNKKTRYCMPNGLKAFLVRNVSDVELLLMHNKTYAAEIAGNVSARKRVEIVEKARALGVKVTNAGAKVRSQE

Entity 25 polymer

描述 description	60S ribosomal protein L33-B
分子量 formula_weight	12133.2 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	f

MPAQGHRLYVKAKHLSFQRSKHVIHPGTSIVKIEGCDSKEEAQFYLGKRVCYVYKSSKAVRGSKIRVIWGTIARPHGNSGAVRARFVHNLPAKTFGSSLRVMLYPSNI

Entity 26 polymer

描述 description	60S ribosomal protein L35
分子量 formula_weight	14333.9 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	h

MALKTFELRKQSQENLAEQLQELRQELASLRVQKIAGGSGSKLSKIKTTRKDIARILTVINESNRLAAREAYKNKKYIPLDLRQKKTRAIRRALTPYEQSRKTLKQIKKERYFPLRKYALKA

Entity 27 polymer

描述 description	60S ribosomal protein L36-B
分子量 formula_weight	11287.4 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	i

MAPGLVVGLNKGKTLTKRQLPERPSRRKGHLSKRTAFVRSIVREVAGFAPYERRVMELIRNSQDKRARKLAKKRLGTLKRAKGKIEELTSVIQSSRLAH

Entity 28 polymer

描述 description	60S ribosomal protein L37-B
分子量 formula_weight	10112.8 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	j

MTKGTQSFGMRHNKSHTICRRCGKRSFHIQKSTCACCGYPAAKTRSYNWGAKAKRRRTTGTGRMSYLKKVHRSFKNGFRSGKPAAAVAASA

Entity 29 polymer

描述 description	Ribosome biogenesis protein nsa2
分子量 formula_weight	29765.5 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	r

MPQNEYIEESIRKHGRRFDHEERKRKKAAREAHDASLYAQKTRGIKAKLYQEKRRKEKIQMKKTIKQHEERNATQRGSDAQTQGAVPTYLLDREQESQAKMLSSAVKQKRKEKAAKYSVPLPQVRGVAEEEMFKVIRTGKSKKNSWKRMITKATFVGDGFTRRPVKYERFIRPMALRQKKANVTHKELGVTMQLPIIGVKKNPQSPTYTQLGVLTKGTVIEVNVSELGLVTSGGKVVWGKYAQITNNPELDGCVNALLLT

Entity 30 polymer

描述 description	GTPase grn1
分子量 formula_weight	52510.4 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	s

MVSLKKKSKRRTTRLRSRIEKKAAESKRKQKRADKKNPQWKSRIPKDPGIPNSFPYKDKILAEIEEQKRIREEEKLARRASGQVDAAMEEEDAVDENGSLMISKIAEAAQASNPDDEEEFVMEEDNLGEAPLLVDSESYEASVKADTSRKAYDKEFKKVVEASDVILYVLDARDPEGTRSKDVERQVLASSAEEKRLIFVINKIDLVPSEVLNKWVTYLRNFFPTIPMRSASGSGNSNLKHQSASASSTISNLLKSLKSYSAKKKLKSSLTVGVIGYPNVGKSSVINALVNRSANGRSAPCPAGNVAGMTTSLREVKLDNKLRLVDSPGIVFPSSDSKDDLYRLVMLNAVSSTKVDDPVAVASYILQFLSRVPGQLERMFQRYELPPLLNTSDIDTATDFLVNIARKRGRLGRGGIPNLNAAANIVINDWHAGRIEWWAEPEVINEKNSSEVQDTQIVTEWAKEFDLNDF

Entity 31 polymer

描述 description	Ribosome biogenesis protein rlp24
分子量 formula_weight	22323.9 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	u

MRVHTCYFCSGPVYPGHGIMFVRNDSKVFRFCRSKCHKNFKMKRNPRKVAWTKAYRKAHGKEMVYDTALAVTAARRNVPVRYDRNVIATTLNAMKRVSQVHAKRERLFYKKRLAGKRAQELQEAQKLIAQNVPQFTEPEGEVETAEVQEPQIVSDEEYTMEEEVAEPVKIPVLAKKRKNKKSRNSSSAMQMD

Entity 32 polymer

描述 description	AdoMet-dependent rRNA methyltransferase spb1
分子量 formula_weight	91055.2 kDa
EC 编号 ec_number	2.1.1.-
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	w

MGKSQKKTAKGRLDKWYKLAKEQGYRSRAAFKLVQLNQKYSFLEKAKVIIDLCAAPGGWLQVASKTCKPGSLIVGVDLAPIKPIPNCHTFVEDITSDKCRSQLRGYLKTWKADVVLHDGAPNVGSAWLQDAYGQAQLVLMSMKLACEFLVAGGTFVTKVFRSRDYNNLLWVFKQLFNKVEATKPPSSRNVSAEIFVVCRGYKAPKKLDPRFTDPRTVFEEVQEPVTNVDAKVFHPEKRKRSREGYADDDYTLHKTVLASEFVTANDPIQILGTSAEIVFPKDDEECQRLYNLDVTTEEILLCCSDLQVLGKKEFRDILRWRLKIRDEMGIGKKVEDEQKTVVEEIPEMDEEERLDQELQDLSEAERVKLKRERRKANQRKQREIVRMQMGMLAPMDIGLEHEAMGEDSLFGLATAEKHGLKELENGTLPVTESVDEEVSTDNEVEYDSDDERDRLEADLDSMYSDYTKRKAESDVKYRVKKARGDLDDEEWNGIDNGTESDDSQIAETNFATPDKDRLTTSLLDKGSTKDGLSRKARMFFDQDIFDGIEDADADVEIMSMNRAAIKKREAELASQNNDDGSKGDQSEDSNDHIEVVPVASAHDEDDDWNSDSDNDENNVEIVTAEAMTLAQDIASRRKSKADLIDEGYNRWSFQSKEGLPDWFLDEETTVNKPNKPITKEAVLALREKMKALNARPIKKVLEAQGRKKMRTIKRLQRVAKKAEGISESGDMTESEKAKEISRLVSRATKSKPKAKPTLVVAKGPNKGLKSRPKGVKGKYKMVDSRMKKDLRAQKRLAKKGRR

Entity 33 polymer

描述 description	Eukaryotic translation initiation factor 6
分子量 formula_weight	26251.4 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	y

MALRAQFENSNEIGVFSNLTNSYALVALGGSENFYSVFEAELGDVVPVVHTTIGGTRIIGRLTCGNRKGLLVPSSTTDNELQHLRNSLPDPVKIQRVDERLSALGNIVACNDYVALVHPDIERETEEIIADVLDVEVFRQTVAGNVLTGSYCALSNQGALVHPRTSIQEQDELSSLLQVPLVAGTINRGSDVIGAGLVVNDWCAFAGLDTTATELAVCESIFKLQDAQPSAIISNRDTLVESYT

Entity 34 polymer

描述 description	UPF0642 protein C32H8.05
分子量 formula_weight	13328.2 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	z

MAKSARSKSIRRNKKVLRENVFQPVIDERTKRLSAHLRDQVNDLTKSSSSKEEGIADNSLKEVSSSEVSDNVGMEVDQPKVSTSGPRDNNRNKWAKKHLKKGKRAKNSNFSKFLKKK

Entity 35 polymer

描述 description	60S ribosomal protein L21-A
分子量 formula_weight	18418.2 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	T

MPHSYGIRARTRYTFQRGFREHGQIRLSTYLKTYKVGDIVDIKVNGAVQKGMPHKYYHGKTGVVYNVTQSSVGVLIYKVVGNRYMEKRVNVRIEHVKHSKCRQDFLDRVKANEAKRKEAKAQGKTVQLRRQPAPPAKAHFVSTENNEPVTLHPVAYDTTI

Entity 36 non-polymer

描述 description	ZINC ION
分子量 formula_weight	65.4 kDa
来源方法 src_method	syn
拷贝数 entity_count	1

▼

6. 折叠分类 (SCOP + CATH) 7 domains

CATH v4.4 (7 domains)

结构域编号 domain_id	8etj301
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	390 — Enolase-like; domain 1
同源超家族 H-superfamily homologous superfamily	110 —

结构域编号 domain_id	8etjN01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	1120 — Ribosomal protein L15e
同源超家族 H-superfamily homologous superfamily	10 — Ribosomal protein L15

结构域编号 domain_id	8etjR01
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	1650 — 50s Ribosomal Protein L19e, Chain O, domain 1
同源超家族 H-superfamily homologous superfamily	10 —

结构域编号 domain_id	8etjW01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	70 — Alpha-Beta Plaits
同源超家族 H-superfamily homologous superfamily	1730 — Ribosomal protein L10, N-terminal RNA-binding domain

结构域编号 domain_id	8etjW02
类 Class class	3 — Alpha Beta
架构 Architecture architecture	90 — Alpha-Beta Complex
拓扑 Topology topology	105 — Molybdopterin biosynthesis moea protein, domain 2
同源超家族 H-superfamily homologous superfamily	20 — Ribosomal protein L10, N-terminal fragment, domain II

结构域编号 domain_id	8etjb01
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	20 — Up-down Bundle
拓扑 Topology topology	120 — Four Helix Bundle (Hemerythrin (Met), subunit A)
同源超家族 H-superfamily homologous superfamily	1190 —

结构域编号 domain_id	8etjb02
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	300 — P-loop containing nucleotide triphosphate hydrolases

▶

7. 引用文献 (1)

▶

晶胞边长 a length_a	1.000 Å
晶胞边长 b length_b	1.000 Å
晶胞边长 c length_c	1.000 Å
晶胞夹角 α angle_alpha	90.00 °
晶胞夹角 β angle_beta	90.00 °
晶胞夹角 γ angle_gamma	90.00 °
晶胞分子数 Z z_pdb	—

空间群 space_group	P 1
空间群编号 int_tables_number	1
晶系 crystal_system	—

分辨率 resolution	3.20 Å
分辨率测定方法 resolution_method	—
颗粒数 num_particles	22000

fit	/app/data/saxs_computation/et/8etj/8etj.fit
pddf	/app/data/pr_computation/et/8etj/8etj.pr.out
profile	/app/data/saxs_computation/et/8etj/8etj.dat

Fkbp39 associated 60S nascent ribosome State 2

SAXS 散射曲线 SAXS Profile

P(r) 距离分布 P(r) Distribution

1. 结构基本信息 1. Structure Basics

2. SAXS 参数 (CRYSOL 理论计算) 2. SAXS Parameters (CRYSOL)

3. P(r) 距离分布 (GNOM 反演) 3. P(r) Analysis (GNOM)

4. 晶体学与实验 4. Crystallography & Experiment

晶胞参数 Unit Cell

对称性 Symmetry

冷冻电镜 EM 3D

5. 实体与聚合体信息 (36)

Entity 1 polymer

聚合体 Polymer

Entity 2 polymer

聚合体 Polymer

Entity 3 polymer

聚合体 Polymer

Entity 4 polymer

聚合体 Polymer

Entity 5 polymer

聚合体 Polymer

Entity 6 polymer

聚合体 Polymer

Entity 7 polymer

聚合体 Polymer

Entity 8 polymer

聚合体 Polymer

Entity 9 polymer

聚合体 Polymer

Entity 10 polymer

聚合体 Polymer

Entity 11 polymer

聚合体 Polymer

Entity 12 polymer

聚合体 Polymer

Entity 13 polymer

聚合体 Polymer

Entity 14 polymer

聚合体 Polymer

Entity 15 polymer

聚合体 Polymer

Entity 16 polymer

聚合体 Polymer

Entity 17 polymer

聚合体 Polymer

Entity 18 polymer

聚合体 Polymer

Entity 19 polymer

聚合体 Polymer

Entity 20 polymer

聚合体 Polymer

Entity 21 polymer

聚合体 Polymer

Entity 22 polymer

聚合体 Polymer

Entity 23 polymer

聚合体 Polymer

Entity 24 polymer

聚合体 Polymer

Entity 25 polymer

聚合体 Polymer

Entity 26 polymer

聚合体 Polymer

Entity 27 polymer

聚合体 Polymer

Entity 28 polymer

聚合体 Polymer

Entity 29 polymer

聚合体 Polymer

Entity 30 polymer

聚合体 Polymer

Entity 31 polymer

聚合体 Polymer

Entity 32 polymer

聚合体 Polymer

Entity 33 polymer

聚合体 Polymer

Entity 34 polymer

聚合体 Polymer

Entity 35 polymer