8fmw

The structure of a hibernating ribosome in the Lyme disease pathogen

Method: ELECTRON MICROSCOPY D_max: 291.6 Å Quality: EXCELLENT

SAXS 散射曲线 SAXS Profile

P(r) 距离分布 P(r) Distribution

下载 Download SAXS (.dat) P(r) (.pr.out) CIF

▼

1. 结构基本信息 1. Structure Basics

条目编号 entry_id	8fmw
沉积日期 deposition_date	2022-12-25
结构标题 title	The structure of a hibernating ribosome in the Lyme disease pathogen
关键词 keywords	hibernating ribosome, bacterial, pathogen, 70S, translation, RIBOSOME; RIBOSOME
实验方法 method	ELECTRON MICROSCOPY

▼

2. SAXS 参数 (CRYSOL 理论计算) 2. SAXS Parameters (CRYSOL)

回转半径 Rg (Guinier) rg_guinier	84.60 Å
回转半径 Rg (电子) rg_electron	85.07 Å
零角强度 I(0) i0	154652000000.00
分子量 molecular_weight	2196400.0 kDa
排除体积 excluded_volume	2268600 Å³
包络体积 envelope_volume	3997900 Å³
水化壳体积 shell_volume	358820 Å³
包络直径 envelope_diameter	298.0 Å
壳层 Rg shell_rg	100.20 Å
包络 Rg envelope_rg	83.39 Å
形状 Rg shape_rg	85.13 Å
总 Rg total_rg	85.02 Å
总原子数 total_atoms	147910
残基数 n_residues	10993
球谐函数阶数 n_harmonics	20
q 范围 q_range	— – 0.5000 Å⁻¹
数据点数 n_points	101
壳层类型 shell_type	directional
溶剂电子密度 solvent_density	0.3340 e/Å³
壳层衬度 contrast_shell	0.0300 e/Å³
CRYSOL 版本 crysol_version	4.1.3

▼

3. P(r) 距离分布 (GNOM 反演) 3. P(r) Analysis (GNOM)

最大尺寸 Dmax dmax	291.6 Å
Rg (实空间) rg_real	86.34 Å
Rg 误差 (实空间) rg_real_error	1.42 Å
I(0) (实空间) i0_real	1.5290e+11
I(0) 误差 (实空间) i0_real_error	2.9520e+09
Rg (倒空间) rg_reciprocal	86.14 Å
I(0) (倒空间) i0_reciprocal	155400000000.0000
解质量估计 total_estimate	0.9009
解质量评级 solution_quality	EXCELLENT a EXCELLENT solution
P(r) 峰数 n_peaks	2
主峰位置 r_peak_primary	113.4 Å
偏度 Skewness skewness	0.317
峰度 Kurtosis kurtosis	-0.040
角度范围 angular_range	— – 0.0900 Å⁻¹
当前正则化参数 α current_alpha	1.2380
最高正则化参数 α highest_alpha	6359000000.0000
实空间数据点数 n_real_points	19
GNOM 版本 gnom_version	4.1.3
质量判据 quality_criteria	AN1: 0.000; Oscil: 0.793; Stabil: 0.921; Sysdev: 1.000; Positv: 1.000; Valcen: 0.908; Smooth: 0.672

▶

4. 晶体学与实验 4. Crystallography & Experiment

▶

5. 实体与聚合体信息 (59)

Entity 1 polymer

描述 description	16S ribosomal RNA
分子量 formula_weight	495137.2 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polyribonucleotide
链编号 strand_id	A
原子数 atom_count	147910

AAAUAACGAAGAGUUUGAUCCUGGCUUAGAACUAACGCUGGCAGUGCGUCUUAAGCAUGCAAGUCAAACGGGAUGUAGCAAUACAUUCAGUGGCGAACGGGUGAGUAACGCGUGGAUGAUCUACCUAUGAGAUGGGGAUAACUAUUAGAAAUAGUAGCUAAUACCGAAUAAGGUCAGUUAAUUUGUUAAUUGAUGAAAGGAAGCCUUUAAAGCUUCGCUUGUAGAUGAGUCUGCGUCUUAUUAGCUAGUUGGUAGGGUAAAUGCCUACCAAGGCAAUGAUAAGUAACCGGCCUGAGAGGGUGAACGGUCACACUGGAACUGAGAUACGGUCCAGACUCCUACGGGAGGCAGCAGCUAAGAAUCUUCCGCAAUGGGCGAAAGCCUGACGGAGCGACACUGCGUGAAUGAAGAAGGUCGAAAGAUUGUAAAAUUCUUUUAUAAAUGAGGAAUAAGCUUUGUAGGAAAUGACAAAGUGAUGACGUUAAUUUAUGAAUAAGCCCCGGCUAAUUACGUGCCAGCAGCCGCGGUAAUACGUAAGGGGCGAGCGUUGUUCGGGAUUAUUGGGCGUAAAGGGUGAGUAGGCGGAUAUAUAAGUCUAUGCAUAAAAUACCACAGCUCAACUGUGGACCUAUGUUGGAAACUAUAUGUCUAGAGUCUGAUAGAGGAAGUUAGAAUUUCUGGUGUAAGGGUGGAAUCUGUUGAUAUCAGAAAGAAUACCGGAGGCGAAGGCGAACUUCUGGGUCAAGACUGACGCUGAGUCACGAAAGCGUAGGGAGCAAACAGGAUUAGAUACCCUGGUAGUCUACGCUGUAAACGAUGCACACUUGGUGUUAACUAAAAGUUAGUACCGAAGCUAACGUGUUAAGUGUGCCGCCUGGGGAGUAUGCUCGCAAGAGUGAAACUCAAAGGAAUUGACGGGGGCCCGCACAAGCGGUGGAGCAUGUGGUUUAAUUCGAUGAUACGCGAGGAACCUUACCAGGGCUUGACAUAUAUAGGAUAUAGUUAGAGAUAAUUAUUCCCCGUUUGGGGUCUAUAUACAGGUGCUGCAUGGUUGUCGUCAGCUCGUGCUGUGAGGUGUUGGGUUAAGUCCCGCAACGAGCGCAACCCUUGUUAUCUGUUACCAGCAUGUAAUGGUGGGGACUCAGAUAAGACUGCCGGUGAUAAGUCGGAGGAAGGUGAGGAUGACGUCAAAUCAUCAUGGCCCUUAUGUCCUGGGCUACACACGUGCUACAAUGGCCUGUACAAAGCGAAGCGAAACAGUGAUGUGAAGCAAAACGCAUAAAGCAGGUCUCAGUCCGGAUUGAAGUCUGAAACUCGACUUCAUGAAGUUGGAAUCGCUAGUAAUCGUAUAUCAGAAUGAUACGGUGAAUACGUUCUCGGGCCUUGUACACACCGCCCGUCACACCACCCGAGUUGAGGAUACCCGAAGCUAUUAUUCUAACCCGUAAGGGAGGAAGGUAUUUAAGGUAUGUUUAGUGAGGGGGGUGAAGUCGUAACAAGGUAGCCGUACUGGAAAGUGCGGCUGGAUC

Entity 2 polymer

描述 description	30S ribosomal protein S3
分子量 formula_weight	23361.7 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	C

GQKVHPYSLRVKINKDWKSKWYFDKKLYSAILHEDFLIRREIMKFLKGIKFDISDIEIIRNNPQKVTVVIVTPRPGSVIGLKGSNLEKIGQLLTKKISKKISIKIKEVKRPELDAQIIANGIAKQVENRASYRKVLKSSLSTSMLKGAQGLKIKIAGRLGGAEIARSFEVKEGRVPLHTLRANIDYGFSEAQTTYGIIGVKVWLFK

Entity 3 polymer

描述 description	30S ribosomal protein S4
分子量 formula_weight	24003.1 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	D

MNRKQIAKGKLVRRFGINIFEQPKYDKILKKKPHPPGMHGKARKAKITEYGKQLIEKQKIKFTYGVSERQLTNTFKEAKKHHGVTGDNLLSILERRIDNVVYRAGFAISRAHARQIVSHGIIILNGRRVTIPSIILRANDQIQIKEKDSLKKLIRSNIEKTSSLRNLPTWIEVNADDLNIKVKHAPSRDEIPTLANEQMVVEYYSKRA

Entity 4 polymer

描述 description	30S ribosomal protein S5
分子量 formula_weight	17030.1 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	E

RKQIEKLISLNRVTKVVKGGRRFSFAAFMVVGDGEGHVGWGFGKANDASDAIKKSLTSARKNLRFVPIRKGTLPHEVIGCFKKAKVLIKPATHGTGVIAGGPVRAVMEALGVHDILSKSLGSNNSMNVVKATFKAFDLVLNAEKVAEMRGKTLKTLWG

Entity 5 polymer

描述 description	30S ribosomal protein S6
分子量 formula_weight	11595.6 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	F

MIKRYEACFLFKSEEIEYKGSLEEVKKSLEFFGATDVVSNFIGERALEYPIKKQARGRYEIIEFSMEGNNLKEFESRLKLIRNLLRYMILVKIVRKI

Entity 6 polymer

描述 description	30S ribosomal protein S7
分子量 formula_weight	18289.3 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	G

MSRKNKKIKKKVFVDTRYNSRIVAKFANRMMYDGKKSISESILYSSIDLLADKLEESDKMAVFYKALDNIKPLVEVRSRRVGGATYQVPVEVREERREALAMKWIIFAARKSSGRSMKEKLSNELLNAYNSTGAAFKKKEDTHRMAEANKAFTHYRW

Entity 7 polymer

描述 description	30S ribosomal protein S8
分子量 formula_weight	14838.5 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	H

MAITYSIGDMLTKLRNASRVGHGSVDLKMSNMNKSILNILKEEGYIKDFNFLEKKGIAFIRVLLKYDNKRNPVINKIDAISTPGRKIYSSYRNMPRIKNGYGILIISSSQGVITGKEAKDKKIGGELICSVW

Entity 8 polymer

描述 description	30S ribosomal protein S9
分子量 formula_weight	14855.1 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	I

FSNVNLSMGTGRRKSSVARVYIREGSGNIKVNNRDFDSYIQLENLRTMALSPLVLTNTLGKYDLYINVYGGGISGQSGAIRHGISRALFKLDESNKMILRSNGFLTRDSRKVERKKFGQKKARKSFQFSKR

Entity 9 polymer

描述 description	30S ribosomal protein S10
分子量 formula_weight	11657.9 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	J

IAKDKIRVRLFSFDVKILDQSAESIVKAVQKAKAQIKGPIPLPTKIKKYTVLRSPHVNKKSREQFEMRTHKRLIDILEPTSALMDSLMKLELPAGVEVDIKQ

Entity 10 polymer

描述 description	30S ribosomal protein S11
分子量 formula_weight	12480.4 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	K

KRNIGEGNVYIQATFNNTIVTVSDIKGNALAWASAGGMGFKGAKKSTPYAAQITAESALNKVRDFGINYVHVYIKGPGIGRESAIRAIGSIGMTVKSISDITPIPHNGCRPKKTRRV

Entity 11 polymer

描述 description	30S ribosomal protein S12
分子量 formula_weight	13823.3 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	L

MPTINQLIRKPRKSQTEKTASPALQNCPQRRGICTRVMTVTPKKPNSALRKVARVRLSNGFEVTAYIPGIGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGAKDTLGVNNRKKGRSKYGTKKPKA

Entity 12 polymer

描述 description	30S ribosomal protein S13
分子量 formula_weight	12936.2 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	M

MARISGIDLPNNKQLKIALTSIYGIGRTRALEVCNKSSISPSKIAKDLDNDEVNRLRKVIESDYIVEGKLRSEVAMSIKRLMDIACYRGVRHRKGLPLRGQRTKTNARTRKGKR

Entity 13 polymer

描述 description	30S ribosomal protein S14 type Z
分子量 formula_weight	7088.6 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	N

AKKSMIIRALRKPKYKTRQNNRCKLCGRPRGYLRDFCMCRICFRKYASEGLIPGVSKSSW

Entity 14 polymer

描述 description	30S ribosomal protein S15
分子量 formula_weight	10241.2 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	O

MIDKKQKQKIVSEFGKNESDTGSVGVQIALITGRIKYLTEHLKINKKDHSSKRGLLKLVGQRRSLLRYYQKKDLEAYRMLISKLGLRK

Entity 15 polymer

描述 description	30S ribosomal protein S16
分子量 formula_weight	9700.5 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	P

MSVKIRLKRMGAKKRPYYRVVVMNSTSPRDGRAIEELGYYHPVEKQNQIKIKEDRMKDWISKGAILSDTVKMLLNKNNLNAKS

Entity 16 polymer

描述 description	30S ribosomal protein S17
分子量 formula_weight	9675.7 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	Q

RENKKELIGKVVSDKMSKTIVVEIVQRKMHPIYHKYLKVSKKVKAHDEKEVSKVGDKVKIIEVRPISKDKRWSLVEVLEKLK

Entity 17 polymer

描述 description	30S ribosomal protein S18
分子量 formula_weight	7417.9 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	R

SCKFCDSGKHPDYKDFDFLKKFITEQGKILPKRITGTSAKHQRRLALEIKRARYMALLPFVKK

Entity 18 polymer

描述 description	30S ribosomal protein S19
分子量 formula_weight	9495.1 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	S

ARSIKKGPFIEKSLYQKVLSSFGSEKRVVIKTYSRSSTIIPEMVSLTISVYNGKTFIPIYITEDLVGHKLGEFSPTRIFRGHAK

Entity 19 polymer

描述 description	30S ribosomal protein S20
分子量 formula_weight	9977.2 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	T

MRKNASALKRSRQNLKRKIRNVSVKSELKTIEKRCINMIKAGKKDEAIEFFKFVAKKLDTAARKRIIHKNKAARKKSRLNVLLLK

Entity 20 polymer

描述 description	30S ribosomal protein S21
分子量 formula_weight	8605.4 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	U

MVTVTVDKNENLEKALKRFKRMIEKEAIIREWKRREYYEKPSTIRVKKEKAFKRKQAKKVRKLKQKTNR

Entity 21 polymer

描述 description	30S ribosomal protein bS22
分子量 formula_weight	3575.6 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	V

MPCGRKRKLKKISTHKRKKKRRKNRHKK

Entity 22 polymer

描述 description	Ribosomal subunit interface protein
分子量 formula_weight	11617.6 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	W

MEPKIQTVNYSLNENEKNFILKKLEKFDTHIKKHIDNLKITIKKEHELFKLDAHIHFNWGKIIHIREDGKILLNLIDSAIARLYKTATKEKEKKNNK

Entity 23 polymer

描述 description	E-site t-RNA
分子量 formula_weight	24417.5 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polyribonucleotide
链编号 strand_id	X

GUCGCUGUAGCUCAGUUGGUAGAGCAUAGGACUGAAAAUCCUUGUGUCAGGAGUUCGAUUCUCCUCGGCGACACCA

Entity 24 polymer

描述 description	23S ribosomal RNA
分子量 formula_weight	948648.2 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polyribonucleotide
链编号 strand_id	AA

UGGUCAAAGUAAUAAGAGUCUAUGGUGAAUGCCUAGGAGCUUUAAGGCGAAGAAGGUCGUGGUAAGCUGCGAAAAGCUUGGGGGAGAAGCAAACAUUUAUUGAUCCCAAGAUUACCGAAUGGAGUAAUCCAGCUAGCAAGAUGCUAGCUAUCUAUUAUUUAAAUAAUAGAGGCGAUACCAGGGGAAGUGAACCAUCUAAGUACCCUGAGGAAAAGAAAUCAAAGAGAUUCCCUUAGUAGUGGCGAGCGAAAAGGGAGUAGCCCAAACUUUAAAUGUGUCAAGCUGCAGAGCGUUGCAUUUAUGGGGUUGUAGGACGUUUAGGCUUAGUCUGUAAUAAGCAAAAAAGUUACAAAAUAUUUAUAUAGAAGAAUAAUCUGGAAAGUUUAACCAAAGAAGGUGAUAGUCCUGUAAUUUAAAUGUAAAUAUCUUUUUAAAAUGUUCCUGAGUAGGACGAGGCACGAGAAACCUUGUUUGAAGCUGGGGAGACCACUCUCCAAGGCUAAAUACUAGAAAGCUACCGAUAGAGAAGAGUACCGUGAGGGAAAGGUGAAAAGAACCCCGGGAGGGGAGUGAAAUAGAACUGAAACCGUAGACUUACAAGCAGUCAAAGCCGUAAUUUAUUGCGGUGAUGGCGUGCCUUUUGCAUAAUGAACCUGCGAGUUAUCAUGUCUAGCAAGAUUAAAGCAUAGAAGUGCUGGAGUCGAAGCGAAAGCGAGUCUUAAAAGGGCGAUUUAGUUAGAUGUGGUAGACCCGAAGCCGAGUGAUCUAUUUAUGGCCAGGCUGAAGCUUGGGUAAAACCAAGUGGAGGGCCGAACUCUAGUCUGUUUAAAAAGGCAGGGAUGAGCUGUGAAUAGGAGUGAAAGGCUAAACAAACUCGGAGAUAGCUGGUUCUCCCCGAAAUGGAUUUAAGUUCAGCCUUAUUUUAGUUUAAUAGAGGUAGAGCACUAAUUGAGCUAGGGCCUGUCAAAGGGUACCAAACUCAGUUAAACUCCGAAUGCUAUUAAAUGAUGAAUAGGAGUGAGACUAUGGGCGAUAAGGUUCAUAGUCGAGAGGGAAACAACCCAGACCAACAGCUAAGGUCUCAAAAAUGUGUUAAGUGGAAAAGGAGGUUUAGGUACGUAAACAGCCAGGAGGUUGGCUUAGAAGCAGCCAUACCUUUAAAGAGUGCGUAAUAGCUCACUGGUCGAGUACUUAAGCGCCGAUAAUGUAACGGGGCUAAACACAUUACCGAAGCUUUGGAUCUUAACGAAAGUUAAGAUGGUAGGGGAGCGUUCUGUAAGCCAGAGAAGUUAAGCUGGAAAGUUUGAUGGAGGUAUCAGAAGUGAGAAUGCAGGUAUGAGUAACGAAAAAAUGGGUGAGAUUCCCAUUCGCCGAAAACCUAAGGUUUCCUGGGUAAAGGUCGUCUUCCCAGGGUUAGUCGGCCCCUAAGGCAAAGCUGAAAAGUGUAGUCGAUGGGAAACGGGUUAAUAUUCCCGUACCUCUUAUAGUUUCGAUGGAGUGACGCAUGAGGUUAACUACUGCUAGGCGAUGGUUGUCCUAGUUUAAGCAUUAAGGCGAUGAUCUUAAUAGGAAAAUCCGUUAAGAGAGCUAAGAUGUGAUGAUGAGUGCUAUUUAGGUAGCAUGAAAUGUAGGUAGUCAAGGUGCCAAGAAAUAGCUUCUAAGGUUAGGCUAUAAGGGACCGUACCGCAAACCGACACAGGUAGGUGGGAUGAAAAUUCUAAGGCGCGCGAGAGAAUCCACGUUAAGGAACUCUGCAAAAUACGUACGUAACUUCGGGAUAAGUACGACCUAAGCAAUUAGGUAGCAUAAAAAUGGUCCAAACGACUGUUUACCAAAAACACAGGUCUCUGCAAAUCUGUAAAGAGAAGUAUAGGGACUGACACCUGCCCGGUGCUGGAAGGUUAAGAGGAGAUGUUAGUUUAUGCGAAGCAUUGAAUUUAAGCCCCAGUAAACGGCGGCCGUAACUAUAACGGUCCUAAGGUAGCGAAAUUCCUUGUCGGGUAAGUUCCGACCCGCACGAAUGGUGUAACGAUUUGGACGCUGUCUCAACGUGGAGCUCGGUGAAAUUGAAGUAUCGGUGAAGAUGCCGAUUACUUGUGGUUAGACGGAAAGACCCCGUGAACCUUUACUAUAGCUUGGUAUUGAGAUUUGAUUAAAUAUGUGUAGGAUAGGUGGGAGACUUUGAAGCUAUCUCGUCAGGGGUAGUGGAGUCAAUCUUGAAAUACCACCCUUGUUUAAUUAGGUUUCUAACUUAUAGAAAUAUGAGGAGAGUGCCAGGUGGGUAGUUUGACUGGGGCGGUCGCCUCCUAAAGAGUAACGGAGGUGCGCAAAGGUUACCUUAGAGUGGUUGGAAAUCACUCUGUAAGUGUAAAGGCAUAAGGUAGCUUAACUGUAAGACUGACAAGUCGAACAGAUACGAAAGUAGGUCUUAGUGAUCUGGCGGUGGCAAGUGGAAGCGCCGUCACUUAACGAAUAAAAGGUACUCCGGGGAUAACAGGCUUAUCCUUCCCAAGAGUUCACAUCGACGGAAGGGUUUGGCACCUCGAUGUCGGCUCAUCGCAUCCUAGGGCUGGAGCAGGUCCUAAGGGUAUGGCUGUUCGCCAUUUAAAGCGGUACGCGAGCUGGGUUCAGAACGUCGUGAGACAGUUUGGUCCCUAUCUGCCACAAGCGUUGGAUAUUUGAGAGGAGCUAUCUUUAGUACGAGAGGACCGAGAUGGACGAACCUCUAGUGUGCCAGUUAUCCUGCCAAGGGUAAGUGCUGGGUAGCUACGUUCGGAAAGGAUAACCGCUGAAAGCAUCUAAGUGGGAAGCCUUCCUCAAGAUGAGAUAUCCUUUAAGGGUCCUGGAAGAAUACCAGGUUGAUAGGUUAGAAGUGUAAGUAUAGCAAUAUAUUAAGCUGACUAAUACUAAUUACCCGUAUCUUUGGCCA

Entity 25 polymer

描述 description	5S ribosomal RNA
分子量 formula_weight	36188.5 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polyribonucleotide
链编号 strand_id	AB

CCCUGGUGGUUAAAGAAAAGAGGAAACACCUGUUAUCAUUCCGAACACAGAAGUUAAGCUCUUAUUCGCUGAUGGUACUGCGAGUUCGCGGGAGAGUAGGUUAUUGCCAGGG

Entity 26 polymer

描述 description	50S ribosomal protein L1
分子量 formula_weight	25177.1 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	AC

KKYIEAFSKVDKNKFYNIEDAILLLKEIKFAKFDETIDISINLNLKKNHTVRDTIVLPNQFMKPKRILVFAKGDRADEARAFGATYVGDDDLINKIKSGWDEFDVVVATPDMMKDVGRLGPILGKRGLMPNPKTQTVTNNLKDAINSLKKGRTEFRANKNGVISFSFGKSSMDNEKIKENYEEFVKEVVKKRPSDLKGAFIDSIYISSTMGPSIKVNFVWR

Entity 27 polymer

描述 description	50S ribosomal protein L2
分子量 formula_weight	30655.6 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	AD

MGIKTYKPKTSSLRYKTTLSFDDLSKGNDPLKSLTKGKKFKSGRDSSGRISIRRRGGGHKRKYRLIDFNRRDKFSIPARVASIEYDPNRSANIALLVYKDGEKRYIISPKGIKVGDVLESGPNAPIKIGNALPLENIPIGRTVHNIELNVGKGGQLIRSAGGYAMILASDGNYVTVKLSSGEMRLIFKKCIATIGEIGNEDYANISIGKAGKSRWLGRRPKVRGVAMNPVDHPHGGGEGKTSGGRHPVSPWGQPTKGYKTRKKKRYSDKFIIKRRNK

Entity 28 polymer

描述 description	50S ribosomal protein L3
分子量 formula_weight	22266.0 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	AE

MLGLIGKKVGMTQIFQKNGIVVPVTVIEFQPNYIIGKKTVDRDGYSALIAGSVDLKSSKVSKPIKGQYKSLKDIEPKRYVIELKGLDGYDAGDEIKVDVFKSVKYVDVTGTTKGKGFQGAMKRHNFSGGPSSHGSKFHRHLGGTGQATTPARTFKGTKMAGRMAGNQQTIQNLEVVLIDEEKRALLVKGAVPGAKGSFVVVKKSKK

Entity 29 polymer

描述 description	50S ribosomal protein L4
分子量 formula_weight	23535.4 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	AF

MERKVFSKDGKEIGTINLDDRVFNIEISHGSIYNAIKNELSNLRVGTSSTKTRSEVRGSSKKPWKQKGTGRARVGTKRNPVWIGGGIALGPKPRDYSYRLPKKVKKLAFKSVLSLRAADENSFKVIENFNVESGKTKDLALIIKNFASFNGKVVILLGNDDQMIKRAGKNIRDLKILSFDKLRVVDLFYAKNLIALESAVNKLNEFYIK

Entity 30 polymer

描述 description	50S ribosomal protein L5
分子量 formula_weight	20445.9 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	AG

MNYVPELKKYYKDSVIKELVKEFEYKSIMQVPKLEKIVISVGVGEAVRNKKLLDSAVLELAQITGQKAVKTKAKKAIAGFKIRQGQEIGAKVTLRGNAMYEFLYKLIHLALPRVKDFRGINGDAFDGNGNYSFGITEQIIFSEIDYDKIERISGLNITIVTTASNDKESKALLLKFGMPFSN

Entity 31 polymer

描述 description	50S ribosomal protein L6
分子量 formula_weight	19972.3 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	AH

MSRIGRLPIKIPDAVKVDVKDNLVIVEGIRGRLVQDIKDSINVKVENGSVIVDRVLNDKKAKAYHGLYRSLIFNMVKGVTEGFSKSLTINGIGYRVEQQGNSLFLSLGYSTQFEYVIPDGISVKLDGNTKISVEGIDKFKVGQVAAEIRSLKKPEPYKGKGIKYDNEVIRRKVGKSGVKK

Entity 32 polymer

描述 description	50S ribosomal protein L9
分子量 formula_weight	17122.0 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	AI

MKVILKEDFINLGKEGDTVEVRDGFARNYLLPKGFAVFSNKHNIEIFNQKRRSILKKQEAKKQMANDLKSKLDLVKLEFFMKSNDSGKLFHSINSLNIADELLKLGFDIERKKIDIHHGTLKTFGTYDVTIKLYEGISSIIKVEIKKE

Entity 33 polymer

描述 description	50S ribosomal protein L10
分子量 formula_weight	18086.4 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	AJ

MSAKINAKKLEMFDLLKQFIDSKQNLFFLDYRGLNVAQLTELRNKIEGEHGSLKVVKNNIMKMVLKEKNINVVDSCLVGPTVVVTALEEANVIAKIFYDFVKSSTLKVKGGFVLGEFYDEAKVQAYSKLPTKKESISLFASVLKAPVSKLARTLKALADVKN

Entity 34 polymer

描述 description	50S ribosomal protein L11
分子量 formula_weight	14731.3 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	AK

KAISWIKLQVPAAQAAPGAKIGQALGPHGVSGPQFVKEFNERTAKMDPGIVVPVIITVYSDKSFSFIVKTPPASILIKKAIGIESGSKKSNTDKVGTISKEKLMEIARIKMSDLNAKSESAAFKIIAGSARSMGVEVEK

Entity 35 polymer

描述 description	50S ribosomal protein L13
分子量 formula_weight	16594.5 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	AL

NKITNNDTIWIKPKTVEKKWYVIDAADRILGKVAVDVVKILRGKHKAYYTPHQDLGDNVIIINASKVKLTGKKYQQKLYYRHSRYPGGLYSDTFRTLSERKPCAPLEIAIKGMLPKGPLGRNLFRNLKVFSGSEHTLKAQNPIKL

Entity 36 polymer

描述 description	50S ribosomal protein L14
分子量 formula_weight	13465.8 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	AM

MIQMQTYLTIADNTGGKVAQCIKVLGGSKRRYAKIGDIITIVVKQAIPNSSVKKGDVYKAVIVRTSKEVRRKNGTYVRFDDNACVILDANLSPRGKRVFGPVARELRDANFMKVVSLASEVI

Entity 37 polymer

描述 description	50S ribosomal protein L15
分子量 formula_weight	16073.0 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	AN

MFNLLKPKGASKRRKIVGRGPGSGLGKTSGRGQKGQKARNTSPRLGFEGGQTPLYRRLPRKGFSNSDYKLEYAIVNLGDIDKKFKDGQVVNYDTLLENKLIKKKNKKIKILSNGKLTKKVSFEVSKISKSAESLVIKIGCTIQLV

Entity 38 polymer

描述 description	50S ribosomal protein L16
分子量 formula_weight	15598.5 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	AO

MLSPKKVKYRKKQRGRLSGEAQKGNKISFGEYGLVSLETNFITARQIEAARIAMTRKIKRGGRVWIRIFPDIPYTKKPAETRMGKGKGGVDHWNAPVKLGTVMFEMSGVVEELAQEAMSLASSKLPVKTMFVVRRDLR

Entity 39 polymer

描述 description	50S ribosomal protein L17
分子量 formula_weight	14308.1 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	AP

MKTKLGFNRLSRKSSHRRALLKNMVISFFKHEKISSTKTKLFEVKRFAERLITRAKVDTVHNRRELSKFIHDKHILNKLFTKISPVFRQRSGGYTRMIKLGKRYGDAAEMAILELVEKPLK

Entity 40 polymer

描述 description	50S ribosomal protein L18
分子量 formula_weight	13753.1 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	AQ

MKKIKEAEQRKLRRKKRIKDKIGRGVASRPRITVFKSNRYFYAQVIDDSKGHTIASISTIEKSLNLGKNIDDVKKLGEVLAKRLKEKNINNLIFDRNGYKYHGLIASFATSLREFGINI

Entity 41 polymer

描述 description	50S ribosomal protein L19
分子量 formula_weight	13544.1 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	AR

MDLIRKIEAQNKKNEAFVFNVGDTVRVVYKIIEGSNERLQSFEGIVISFQNKGIGKTFLIRKISSGIGVEKIFPVYSPIIEKVEVLRRGKVRRAKLYYMRNRIGKAAMKIKERLTIK

Entity 42 polymer

描述 description	50S ribosomal protein L20
分子量 formula_weight	13416.0 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	AS

ARAKNGTVHVARRKRILKKTKGFWGTKKSNYKKAKDTLRKGMMYATRDRKVRKRDFRRLWISRISAALSDTGVTYSRFIEGLLKSNIKINRKILSNLAIEDVEAFKKIVLEIRR

Entity 43 polymer

描述 description	50S ribosomal protein L21
分子量 formula_weight	12204.2 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	AT

MYALVEINGKQYKAIEGEFLKIDKISPVEKDKLEFNSVLLINKDGEVKIGKPYVVNSLIRCTYKEDKKDKKVVSYRYRRRKSSERKVGHRQTYSYILVDEIVF

Entity 44 polymer

描述 description	50S ribosomal protein L22
分子量 formula_weight	13150.5 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	AU

LVNRRYTAKGKNLPSSPKKVRPIADNIRGESYIKAIAVLCSMPNKGAKLLEKVVKSAASNAMYHNKNLSEDMIFVKTVMVDDGRRRKKIWPRARGRADRLVNRNCHIFVEVDEKK

Entity 45 polymer

描述 description	50S ribosomal protein L23
分子量 formula_weight	11164.2 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	AV

MKAYDIIVSPMLTEKTNTQRESINVYVFKVNKRANKKEVGAAIKELFNVTPVSCNLLNIKSKAKVVVSRKGYPIGKGKTSSWKKAYVYLKKEDKIDIF

Entity 46 polymer

描述 description	50S ribosomal protein L24
分子量 formula_weight	11467.8 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	AW

MKTKLKIGDSVKILSGKDRGRIGKIASINRKKNKVIVESCNMVKKVIKARTPQEKGRIIDKEAAIDISNVMIFVKGTSSRLGIRFENNEKIRYLKKNGQRI

Entity 47 polymer

描述 description	50S ribosomal protein L25
分子量 formula_weight	20347.4 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	AX

ENSRVLSCQYRSSFGSSNARRIRAKSEIPAVVYGQGKDVSHLRIKSSEFNKKFAKFTDNTVLILDDGKLERCVFVKDAAENIASKLIYHIDFYEVDRNVELEKYVPIKLIGASIGVKEGGILTVLKEQVKVRSLPLDLPEFIELDLTPVNKGDSVLLKDLVLPSNVRLAENDENLEVVIIK

Entity 48 polymer

描述 description	50S ribosomal protein L27
分子量 formula_weight	8104.5 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	AY

GSSKNGRDSISKRLGVKRSGGQFVKAGEIIVRQRGTKFHKGKNVGLGRDYTIFALSSGKVEFKTLKGRKYVSIV

Entity 49 polymer

描述 description	50S ribosomal protein L28
分子量 formula_weight	10069.1 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	AZ

ARKCEITGKKTMFGNNVPRKGLAKKKGGAGQHIGVKTKRTFKVNLINKKFFIPNLGRSVSIKVSANALRSISKIGLDAFLKKNCKKIENFL

Entity 50 polymer

描述 description	50S ribosomal protein L29
分子量 formula_weight	7915.5 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	Aa

MKNFKNFTLEDMKAKRLELKKEYLDLRFKSVVGHVENPLKKREIRRDIARLNTMICEYELGIRKV

Entity 51 polymer

描述 description	50S ribosomal protein uL30
分子量 formula_weight	11661.2 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	Ab

IKRKLRLQLKKARFNASRSRSKNKCFIKRMENNRKIISKNNINVQVFLVRSLIGKLNKKVKVLKALGLNKIGDKKVHFLNESIKGMLNETINMILLSEVM

Entity 52 polymer

描述 description	50S ribosomal protein L31 type B
分子量 formula_weight	9318.7 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	Ac

MRKDIHPKNNLVVFKDGSNGAMFLTKSTLNSKETIKYIDGKEYPLVTVEITSKSHPFYTGQQKFVDAAGRIDKFNKRYKKS

Entity 53 polymer

描述 description	50S ribosomal protein L32
分子量 formula_weight	6960.2 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	Ad

AVPKFKPSKSRSRTRRSINMRKKIPQFQECSNCGNLGVRHRICLKCGYYRNNQYLEIGL

Entity 54 polymer

描述 description	50S ribosomal protein L33
分子量 formula_weight	6100.3 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	Ae

AVELISLICEETGIRNYTTTKNRRNKQEKLELMKYCPKLRKHTLHKEGKIK

Entity 55 polymer

描述 description	50S ribosomal protein L34
分子量 formula_weight	6059.4 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	Af

MKRTYQPSRVKRNRKFGFRARMKTKGGRLILSRRRAKGRMKLTVSDEKKK

Entity 56 polymer

描述 description	50S ribosomal protein L35
分子量 formula_weight	7840.5 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	Ag

MANKMKTRKSAKKRYSFTVNGKVKYKKQNLRHILTKKSSKRKRNLRKSGNLSCFEVKRIKTLLPYG

Entity 57 polymer

描述 description	50S ribosomal protein L36
分子量 formula_weight	4418.6 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	Ah

MKVRVSVKPICEKCKVIKRKGVLRIICDNLKHKQRQK

Entity 58 polymer

描述 description	50S ribosomal protein bL38
分子量 formula_weight	5351.3 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	Ai

RVGSKELISRWGGKIIMKSKFENGKIKHYAECQTSKNTARKPRDLF

Entity 59 non-polymer

描述 description	ZINC ION
分子量 formula_weight	65.4 kDa
来源方法 src_method	syn
拷贝数 entity_count	4

▶

7. 引用文献 (1)

▶

晶胞边长 a length_a	1.000 Å
晶胞边长 b length_b	1.000 Å
晶胞边长 c length_c	1.000 Å
晶胞夹角 α angle_alpha	90.00 °
晶胞夹角 β angle_beta	90.00 °
晶胞夹角 γ angle_gamma	90.00 °
晶胞分子数 Z z_pdb	—

空间群 space_group	P 1
空间群编号 int_tables_number	1
晶系 crystal_system	triclinic

分辨率 resolution	2.86 Å
分辨率测定方法 resolution_method	—
颗粒数 num_particles	288776

fit	/app/data/saxs_computation/fm/8fmw/8fmw.fit
pddf	/app/data/pr_computation/fm/8fmw/8fmw.pr.out
profile	/app/data/saxs_computation/fm/8fmw/8fmw.dat

The structure of a hibernating ribosome in the Lyme disease pathogen

SAXS 散射曲线 SAXS Profile

P(r) 距离分布 P(r) Distribution

1. 结构基本信息 1. Structure Basics

2. SAXS 参数 (CRYSOL 理论计算) 2. SAXS Parameters (CRYSOL)

3. P(r) 距离分布 (GNOM 反演) 3. P(r) Analysis (GNOM)

4. 晶体学与实验 4. Crystallography & Experiment

晶胞参数 Unit Cell

对称性 Symmetry

冷冻电镜 EM 3D

5. 实体与聚合体信息 (59)

Entity 1 polymer

聚合体 Polymer

Entity 2 polymer

聚合体 Polymer

Entity 3 polymer

聚合体 Polymer

Entity 4 polymer

聚合体 Polymer

Entity 5 polymer

聚合体 Polymer

Entity 6 polymer

聚合体 Polymer

Entity 7 polymer

聚合体 Polymer

Entity 8 polymer

聚合体 Polymer

Entity 9 polymer

聚合体 Polymer

Entity 10 polymer

聚合体 Polymer

Entity 11 polymer

聚合体 Polymer

Entity 12 polymer

聚合体 Polymer

Entity 13 polymer

聚合体 Polymer

Entity 14 polymer

聚合体 Polymer

Entity 15 polymer

聚合体 Polymer

Entity 16 polymer

聚合体 Polymer

Entity 17 polymer

聚合体 Polymer

Entity 18 polymer

聚合体 Polymer

Entity 19 polymer

聚合体 Polymer

Entity 20 polymer

聚合体 Polymer

Entity 21 polymer

聚合体 Polymer

Entity 22 polymer

聚合体 Polymer

Entity 23 polymer

聚合体 Polymer

Entity 24 polymer

聚合体 Polymer

Entity 25 polymer

聚合体 Polymer

Entity 26 polymer

聚合体 Polymer

Entity 27 polymer

聚合体 Polymer

Entity 28 polymer

聚合体 Polymer

Entity 29 polymer

聚合体 Polymer

Entity 30 polymer

聚合体 Polymer

Entity 31 polymer

聚合体 Polymer

Entity 32 polymer

聚合体 Polymer

Entity 33 polymer

聚合体 Polymer

Entity 34 polymer

聚合体 Polymer

Entity 35 polymer