Entity 1
polymer
| 描述 description | ATP-dependent translocase ABCB1 |
| 分子量 formula_weight | 146063.9 kDa |
| EC 编号 ec_number | 7.6.2.2,7.6.2.1 |
| 突变 mutation | ;GLN A 83 UNP P21447 ASN 83 ENGINEERED MUTATION GLN A 87 UNP P21447 ASN 87 ENGINEERED MUTATION GLN A 90 UNP P21447 ASN 90 ENGINEERED MUTATION ALA A 133 UNP P21447 CYS 133 ENGINEERED MUTATION CYS A 335 UNP P21447 LEU 335 ENGINEERED MUTATION GLY A 427 UNP P21447 CYS 427 ENGINEERED MUTATION ALA A 713 UNP P21447 CYS 713 ENGINEERED MUTATION ALA A 952 UNP P21447 CYS 952 ENGINEERED MUTATION GLY A 1070 UNP P21447 CYS 1070 ENGINEERED MUTATION ARG A 1121 UNP P21447 CYS 1121 ENGINEERED MUTATION VAL A 1223 UNP P21447 CYS 1223 ENGINEERED MUTATION
; |
| 来源方法 src_method | man |
| 拷贝数 entity_count | 1 |
聚合体 Polymer
| 聚合体类型 type | polypeptide(L) |
| 链编号 strand_id | A |
| 原子数 atom_count | 9217 |
MELEEDLKGRADKNFSKMGKKSKKEKKEKKPAVSVLTMFRYAGWLDRLYMLVGTLAAIIHGVALPLMMLIFGDMTDSFASVGQVSKQSTQMSEADKRAMFAKLEEEMTTYAYYYTGIGAGVLIVAYIQVSFWALAAGRQIHKIRQKFFHAIMNQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGMFFQAMATFFGGFIIGFTRGWKLTLVILAISPVLGLSAGIWAKILSSFTDKELHAYAKAGAVAEEVLAAIRTVIAFGGQKKELERYNNNLEEAKRLGIKKAITANISMGAAFLLIYASYALAFWYGTSLVISKEYSIGQVLTVFFSVCIGAFSVGQASPNIEAFANARGAAYEVFKIIDNKPSIDSFSKSGHKPDNIQGNLEFKNIHFSYPSRKEVQILKGLNLKVKSGQTVALVGNSGGGKSTTVQLMQRLYDPLDGMVSIDGQDIRTINVRYLREIIGVVSQEPVLFATTIAENIRYGREDVTMDEIEKAVKEANAYDFIMKLPHQFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQAALDKAREGRTTIVIAHRLSTVRNADVIAGFDGGVIVEQGNHDELMREKGIYFKLVMTQTAGNEIELGNEAGKSKDEIDNLDMSSKDSGSSLIRRRSTRKSITGPHDQDRKLSTKEALDEDVPPASFWRILKLNSTEWPYFVVGIFAAIINGGLQPAFSVIFSKVVGVFTNGGPPETQRQNSNLFSLLFLILGIISFITFFLQGFTFGKAGEILTKRLRYMVFKSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGATGSRLAVIFQNIANLGTGIIISLIYGWQLTLLLLAIVPIIAIAGVVEMKMLSGQALKDKKELEGSGKIATEAIENFRTVVSLTREQKFETMYAQSLQIPYRNAMKKAHVFGITFSFTQAMMYFSYAAAFRFGAYLVTQQLMTFENVLLVFSAIVFGAMAVGQVSSFAPDYAKATVSASHIIRIIEKTPEIDSYSTQGLKPNMLEGNVQFSGVVFNYPTRPSIPVLQGLSLEVKKGQTLALVGSSGGGKSTVVQLLERFYDPMAGSVFLDGKEIKQLNVQWLRAQLGIVSQEPILFDRSIAENIAYGDNSRVVSYEEIVRAAKEANIHQFIDSLPDKYNTRVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTVIVIAHRLSTIQNADLIVVIQNGKVKEHGTHQQLLAQKGIYFSMVSVQAGAKRSLEENLYFQGGGASGGSWSHPQFEKAAAGGGSGGGSWSHPQFEKGSGHHHHHH
来源 Source
| 来源生物 organism | Mus musculus |
| 通用名 common_name | house mouse |
| NCBI 分类编号 ncbi_taxonomy_id | 10090 |
| 宿主生物 host_organism | Komagataella pastoris |
Entity 2
non-polymer
| 描述 description | ;(4S,11S,18S)-4-[[(2,4-dinitrophenyl)disulfanyl]methyl]-11,18-dimethyl-6,13,20-trithia-3,10,17,22,23,24-hexazatetracyclo[17.2.1.1^{5,8}.1^{12,15}]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione
; |
| 分子量 formula_weight | 692.8 kDa |
| 来源方法 src_method | syn |
| 拷贝数 entity_count | 1 |
Entity 3
non-polymer
| 描述 description | ;(4~{S},11~{S},18~{S})-4,11-dimethyl-18-(sulfanylmethyl)-6,13,20-trithia-3,10,17,22,23,24-hexazatetracyclo[17.2.1.1^{5,8}.1^{12,15}]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione
; |
| 分子量 formula_weight | 494.6 kDa |
| 来源方法 src_method | syn |
| 拷贝数 entity_count | 1 |
Entity 4
non-polymer
| 描述 description | CHOLESTEROL HEMISUCCINATE |
| 分子量 formula_weight | 486.7 kDa |
| 来源方法 src_method | syn |
| 拷贝数 entity_count | 5 |
