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8u80

KCTD5/Cullin3/Gbeta1gamma2 Complex: Local Refinment of KCTD5(BTB)/Cullin3(NTD)

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

BTB/POZ domain-containing protein KCTD5

Homo sapiens

UniProt Q9NXV2

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 10 Cullin-3 × 5 （Q13618） Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers
3drx 3dry 3drz

3 assemblies

Heteromeric or nucleic-acid complex
8u7z 8u80 8u81 8u82 8u83 8u84

6 assemblies

View Construct and Data Evidence
UniProt name KCTD5_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain K1； PDBConstruct 1–234； UniProt 1–234 Author chain K2； PDBConstruct 1–234； UniProt 1–234 Author chain K3； PDBConstruct 1–234； UniProt 1–234 Author chain K4； PDBConstruct 1–234； UniProt 1–234 Author chain K5； PDBConstruct 1–234； UniProt 1–234

Cullin-3

Homo sapiens

UniProt Q13618

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 10 BTB/POZ domain-containing protein KCTD5 × 5 （Q9NXV2） Consistent with protein count

Other States of the Same Protein in the Database

Monomer
2myl 2mym

2 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
4ap2 4apf 4eoz 4eoz 4eoz 4hxi 5nlb 6i2m 8gq6 8h33 8h34 8h35

30 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name CUL3_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain C1； PDBConstruct 1–381； UniProt 1–381 Author chain C2； PDBConstruct 1–381； UniProt 1–381 Author chain C3； PDBConstruct 1–381； UniProt 1–381 Author chain C4； PDBConstruct 1–381； UniProt 1–381 Author chain C5； PDBConstruct 1–381； UniProt 1–381

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id8u80
Deposition date deposition_date2023-09-15
Structure title titleKCTD5/Cullin3/Gbeta1gamma2 Complex: Local Refinment of KCTD5(BTB)/Cullin3(NTD)
Keywords keywords;cullin family protein, proteasome-mediated ubiquitin-dependent protein catabolic process, complex, ubiquitin-dependent protein catabolic process, LIGASE ;; LIGASE
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

8u80__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

8u80__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

8u80__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）64.85 Å
Rg (electron density)65.57 Å
Total Rg65.31 Å
Atom count38457
Residues2360
Excluded volume342990 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 8u80__assembly_1__model_1 decameric （10） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (2)

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7. Citations (3)