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9cnv

HIV-2 CA hexamer bound with CPSF6 peptide; assembled via liposome templating

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Capsid protein p24

Human immunodeficiency virus 2

UniProt P18042

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 12 Isoform 2 of Cleavage and polyadenylation specificity factor subunit 6 × 6 （Q16630） INOSITOL HEXAKISPHOSPHATE × 12 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 2 Isoform 2 of Cleavage and polyadenylation specificity factor subunit 6 × 1 （Q16630） INOSITOL HEXAKISPHOSPHATE × 2 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1nc8 2e1x 2iwj 9clj 9clj

5 assemblies

Homodimer

None

Homotetramer
9cnt

1 assemblies

Other homooligomers
9clj 9clj 9clj 9cns 9cns 9cnt

6 assemblies

Heteromeric or nucleic-acid complex
9cnu 9cnu 9cnv 9cnv

4 assemblies

View Construct and Data Evidence
UniProt name POL_HV2G1
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–231； UniProt 136–366

Isoform 2 of Cleavage and polyadenylation specificity factor subunit 6

OrganismNot specified

UniProt Q16630

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 12 Capsid protein p24 × 6 （P18042） INOSITOL HEXAKISPHOSPHATE × 12 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 2 Capsid protein p24 × 1 （P18042） INOSITOL HEXAKISPHOSPHATE × 2 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
3p5t 3p5t 3p5t 3p6y 3p6y 3p6y 3p6y 3q2s 3q2t 4b4n 4u0a 4u0b

25 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name CPSF6_HUMAN
Isoform Q16630-2
PDB entities 2
Chains and sequence ranges Author chain B； PDBConstruct 1–15； UniProt 313–327

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id9cnv
Deposition date deposition_date2024-07-15
Structure title titleHIV-2 CA hexamer bound with CPSF6 peptide; assembled via liposome templating
Keywords keywordsHIV-2, Capsid, IP6, CPSF6, VIRAL PROTEIN; VIRAL PROTEIN
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

9cnv__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

9cnv__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

9cnv__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）34.73 Å
Rg (electron density)35.23 Å
Total Rg35.36 Å
Atom count11388
Residues1398
Excluded volume200140 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 9cnv__assembly_1__model_1 dodecameric （12） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 9cnv__assembly_2__model_1 dimeric （2） Excluded — —
Exclusion reason： Auxiliary symmetry representation; not a complete or representative biological assembly.
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

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7. Citations (1)