9fab
Additional cryo-EM structure of cardiac amyloid AL59 - bent polymorph
SAXS 散射曲线 SAXS Profile
P(r) 距离分布 P(r) Distribution
1. 结构基本信息 1. Structure Basics
| 条目编号 entry_id | 9fab |
| 沉积日期 deposition_date | 2024-05-10 |
| 结构标题 title | Additional cryo-EM structure of cardiac amyloid AL59 - bent polymorph |
| 关键词 keywords | systemic AL amyloid fibril, PROTEIN FIBRIL; PROTEIN FIBRIL |
| 实验方法 method | ELECTRON MICROSCOPY |
2. SAXS 参数 (CRYSOL 理论计算) 2. SAXS Parameters (CRYSOL)
| 回转半径 Rg (Guinier) rg_guinier | 31.29 Å |
| 回转半径 Rg (电子) rg_electron | 32.03 Å |
| 零角强度 I(0) i0 | 64311200.00 |
| 分子量 molecular_weight | 62449.0 kDa |
| 排除体积 excluded_volume | 77799 ų |
| 包络体积 envelope_volume | 103870 ų |
| 水化壳体积 shell_volume | 29790 ų |
| 包络直径 envelope_diameter | 112.8 Å |
| 壳层 Rg shell_rg | 35.41 Å |
| 包络 Rg envelope_rg | 32.16 Å |
| 形状 Rg shape_rg | 32.03 Å |
| 总 Rg total_rg | 32.31 Å |
| 总原子数 total_atoms | 8665 |
| 残基数 n_residues | 585 |
| 球谐函数阶数 n_harmonics | 20 |
| q 范围 q_range | — – 0.5000 Å−1 |
| 数据点数 n_points | 101 |
| 壳层类型 shell_type | directional |
| 溶剂电子密度 solvent_density | 0.3340 e/ų |
| 壳层衬度 contrast_shell | 0.0300 e/ų |
| CRYSOL 版本 crysol_version | 4.1.3 |
3. P(r) 距离分布 (GNOM 反演) 3. P(r) Analysis (GNOM)
| 最大尺寸 Dmax dmax | 107.2 Å |
| Rg (实空间) rg_real | 31.64 Å |
| Rg 误差 (实空间) rg_real_error | 1.15 Å |
| I(0) (实空间) i0_real | 6.4310e+07 |
| I(0) 误差 (实空间) i0_real_error | 1.1710e+06 |
| Rg (倒空间) rg_reciprocal | 31.50 Å |
| I(0) (倒空间) i0_reciprocal | 64300000.0000 |
| 解质量估计 total_estimate | 0.8057 |
| 解质量评级 solution_quality | GOOD a GOOD solution |
| P(r) 峰数 n_peaks | 2 |
| 主峰位置 r_peak_primary | 29.4 Å |
| 偏度 Skewness skewness | 0.579 |
| 峰度 Kurtosis kurtosis | -0.190 |
| 角度范围 angular_range | — – 0.2550 Å−1 |
| 当前正则化参数 α current_alpha | 0.0000 |
| 最高正则化参数 α highest_alpha | 16640000.0000 |
| 实空间数据点数 n_real_points | 52 |
| GNOM 版本 gnom_version | 4.1.3 |
| 质量判据 quality_criteria | AN1: 0.000; Oscil: 0.775; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.651; Smooth: 0.495 |