9pvg
Co-crystal structure of two CCM2 PTB domains bound to a KRIT1 peptide encompassing NPxF2 and NPxF3
SAXS Profile
P(r) Distribution
1. Structure Basics
| entry_id | 9pvg |
| deposition_date | 2025-08-01 |
| last_revision | 2026-01-28 |
| title | Co-crystal structure of two CCM2 PTB domains bound to a KRIT1 peptide encompassing NPxF2 and NPxF3 |
| keywords | PTB domain, NPxY, NPxF, Cerebral Cavernous Malformations, CCM, protein-protein, SIGNALING PROTEIN; SIGNALING PROTEIN |
| method | X-RAY DIFFRACTION |
Download Data
2. SAXS Parameters (CRYSOL)
| rg_guinier | 31.96 Å |
| rg_electron | 31.42 Å |
| i0 | 65017700.00 |
| molecular_weight | 64895.0 kDa |
| excluded_volume | 81904 ų |
| envelope_volume | 107800 ų |
| shell_volume | 30403 ų |
| envelope_diameter | 109.2 Å |
| shell_rg | 35.92 Å |
| envelope_rg | 31.22 Å |
| shape_rg | 31.42 Å |
| total_rg | 31.85 Å |
| total_atoms | 4573 |
| n_residues | 584 |
| n_harmonics | 20 |
| q_range | — – 0.5000 Å−1 |
| n_points | 101 |
| shell_type | directional |
| solvent_density | 0.3340 e/ų |
| contrast_shell | 0.0300 e/ų |
| crysol_version | 4.1.3 |
3. P(r) Analysis (GNOM)
| dmax | 108.8 Å |
| rg_real | 32.20 Å |
| rg_real_error | 0.84 Å |
| i0_real | 6.5020e+07 |
| i0_real_error | 1.1130e+06 |
| rg_reciprocal | 32.10 Å |
| i0_reciprocal | 65010000.0000 |
| total_estimate | 0.6560 |
| solution_quality | REASONABLE a REASONABLE solution |
| n_peaks | 1 |
| r_peak_primary | 28.3 Å |
| skewness | 0.468 |
| kurtosis | -0.408 |
| angular_range | — – 0.2500 Å−1 |
| current_alpha | 0.0000 |
| highest_alpha | 53330000.0000 |
| n_real_points | 51 |
| gnom_version | 4.1.3 |
| quality_criteria | AN1: 0.000; Oscil: 0.776; Stabil: 1.000; Sysdev: 0.169; Positv: 1.000; Valcen: 0.843; Smooth: 0.847 |