← Back to search
← Back to search
9qje

;USP7 Covalently Bound to N-(6-Fluoro-3-nitropyridin-2-yl)-5-(1-methyl-1H-pyrazol-4-yl)isoquinolin-3-amine (GCL36, 7a) with Partial Occupancy ;

Method: X-RAY DIFFRACTION Dmax: 104.1 Å Quality: GOOD

SAXS Profile

SAXS profile for 9qje

P(r) Distribution

P(r) distribution for 9qje
▼

1. Structure Basics

entry_id9qje
deposition_date2025-03-19
title;USP7 Covalently Bound to N-(6-Fluoro-3-nitropyridin-2-yl)-5-(1-methyl-1H-pyrazol-4-yl)isoquinolin-3-amine (GCL36, 7a) with Partial Occupancy ;
keywordsCovalent, SNAr, Inhibitor, HYDROLASE; HYDROLASE
methodX-RAY DIFFRACTION
▼

Download Data

▼

2. SAXS Parameters (CRYSOL)

rg_guinier29.94 Å
rg_electron29.23 Å
i0171847000.00
molecular_weight69609.0 kDa
excluded_volume67248 ų
envelope_volume117840 ų
shell_volume34109 ų
envelope_diameter108.4 Å
shell_rg35.60 Å
envelope_rg29.65 Å
shape_rg29.18 Å
total_rg29.76 Å
total_atoms5249
n_residues676
n_harmonics20
q_range— – 0.5000 Å−1
n_points101
shell_typedirectional
solvent_density0.3340 e/ų
contrast_shell0.0300 e/ų
crysol_version4.1.3
▼

3. P(r) Analysis (GNOM)

dmax104.1 Å
rg_real29.97 Å
rg_real_error0.99 Å
i0_real1.7180e+08
i0_real_error2.9940e+06
rg_reciprocal29.96 Å
i0_reciprocal171800000.0000
total_estimate0.8712
solution_quality GOOD a GOOD solution
n_peaks2
r_peak_primary33.4 Å
skewness0.385
kurtosis-0.206
angular_range— – 0.2650 Å−1
current_alpha0.0000
highest_alpha18350000.0000
n_real_points54
gnom_version4.1.3
quality_criteria AN1: 0.000; Oscil: 0.803; Stabil: 0.998; Sysdev: 1.000; Positv: 1.000; Valcen: 0.958; Smooth: 0.961
▶

4. Crystallography & Experiment

▶

5. Entities & Polymer Info (6)

▶

6. Citations (1)

▶

7. Files & Curves (10)