{
  "code": "SASDXE6",
  "status": "Published",
  "type_of_curve": "SEC-SAS",
  "angular_unit": "1/A",
  "project": {
    "title": "Allosteric network of dynamic coupling within BAP1-UCH revealed by methyl NMR.",
    "publication": {
      "title": "Allosteric network of dynamic coupling within BAP1-UCH revealed by methyl NMR.",
      "author_list": "Lai CH, Lou YC, Chang CF, Lu WL, Sriramoju MK, Wang YS, Wu KP, Camilloni C, Hsu SD",
      "journal": "Nat Commun",
      "doi": "10.1038/s41467-026-73600-4",
      "pmid": "42191708",
      "published_date": "2026 May 26"
    },
    "status": "released",
    "submitted_date": "2025-07-10",
    "released_date": "2026-04-30"
  },
  "pddf_data": "https://www.sasbdb.org/media/p_of_R_files/SASDXE6.out",
  "intensities_data": "https://www.sasbdb.org/media/intensities_files/SASDXE6.dat",
  "intensities_log_plot": "https://www.sasbdb.org/media/intensities_files/scattering_plots/SASDXE6_dat_img.png",
  "intensities_kratky_plot": "https://www.sasbdb.org/media/intensities_files/scattering_plots/SASDXE6_kratky_img.png",
  "pddf_plot": "https://www.sasbdb.org/media/p_of_R_files/pofr_images/SASDXE6_pofr_img.png",
  "intensities_guinier_plot": "https://www.sasbdb.org/media/intensities_files/scattering_plots/SASDXE6_guinier_img.png",
  "sascif_data": "https://www.sasbdb.org/media/sascif/sascif_files/SASDXE6.sascif",
  "experiment": {
    "instrument": {
      "detector": {
        "type": null,
        "name": "Eiger X 1M and Eiger X 9M",
        "resolution": 75.0
      },
      "name": "Taiwan Photon Source, NSRRC",
      "city": "Hsinchu",
      "country": "Taiwan",
      "beamline_name": "13A",
      "beam_geometry": null,
      "type_of_source": "X-ray synchrotron",
      "point_source": null,
      "line_collimation": null,
      "sample_path_length": null,
      "line_collimation_slitlength": null,
      "line_collimation_integrationwidth": null,
      "xray_energy": null,
      "beam_profile_ah": null,
      "beam_profile_al": null
    },
    "sample": {
      "molecule": [
        {
          "long_name": "Ubiquitin C-terminal hydrolase (UCH) domain of BAP1 L49V",
          "short_name": null,
          "sequence": "SNGMNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQGPVYGFIFVFKWIEERRSRR\r\nKVSTLVDDTSVIDDDIVNNMFFAHQLIPNSCATHALLSVLLNCSSVDLGPTLSRMKDFTK\r\nGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPITGRL\r\nFELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRR",
          "organism": null,
          "uniprot_code": "Q92560",
          "uniprot_range_first": 1,
          "uniprot_range_last": 238,
          "oligomerization": "monomer",
          "molecular_type": "protein",
          "uniprot_sequence": "MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQGPVYGFIFLFKWIEERRSRR\nKVSTLVDDTSVIDDDIVNNMFFAHQLIPNSCATHALLSVLLNCSSVDLGPTLSRMKDFTK\nGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPITGRL\nFELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRRIK\nYEARLHVLKVNRQTVLEALQQLIRVTQPELIQTHKSQESQLPEESKSASNKSPLVLEANR\nAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAF\nLDNHNYAKSPMQEEEDLAAGVGRSRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSALRYKG\nKGTGKPGALSGSADGQLSVLQPNTINVLAEKLKESQKDLSIPLSIKTSSGAGSPAVAVPT\nHSQPSPTPSNESTDTASEIGSAFNSPLRSPIRSANPTRPSSPVTSHISKVLFGEDDSLLR\nVDCIRYNRAVRDLGPVISTGLLHLAEDGVLSPLALTEGGKGSSPSIRPIQGSQGSSSPVE\nKEVVEATDSREKTGMVRPGEPLSGEKYSPKELLALLKCVEAEIANYEACLKEEVEKRKKF\nKIDDQRRTHNYDEFICTFISMLAQEGMLANLVEQNISVRRRQGVSIGRLHKQRKPDRRKR\nSRPYKAKRQ",
          "mw": 27.194,
          "total_mw": 27.194,
          "number_molecules": 1,
          "complex_state": false,
          "deuteration": null,
          "molecule_source": "biological",
          "molecule_description": ""
        }
      ],
      "buffer": {
        "name": "20 mM HEPES, 150 mM NaCl, 1 mM TCEP, 0.02% NaN3",
        "concentration_unit": null,
        "comment": null,
        "additive": null,
        "concentration": null,
        "pka": null,
        "ph": 7.5,
        "deuteration": null
      },
      "purity_method": null,
      "name": "Ubiquitin C-terminal hydrolase (UCH) domain of BAP1 point mutation (L49V)",
      "ext_coefficient": null,
      "contrast": null,
      "specific_vol": null,
      "dry_vol": null,
      "absorbption": null,
      "deuteration": null,
      "mixture": null
    },
    "contributor": [
      {
        "affiliation": [
          {
            "short_name": null,
            "address": "Taipei, Taiwan",
            "full_name": "Academia Sinica",
            "webpage": "https://www.sinica.edu.tw"
          }
        ],
        "contributor_name": "Yong-Sheng",
        "contributor_surname": "Wang",
        "orcid": "https://orcid.org/0000-0002-4868-4507"
      }
    ],
    "concentration_method": null,
    "concentration_unit": null,
    "date": "2024-06-23",
    "storage_temperature": 4.0,
    "cell_temperature": 10.0,
    "exposure_time": 2.0,
    "number_of_frames": 11,
    "wavelength": 0.0826,
    "sample_detector_distance": 9.0,
    "concentration_min": null,
    "concentration_max": 12.0,
    "sample_volume": 90.0,
    "flow_rate": 0.1,
    "s_min": 0.07,
    "s_max": 24.558,
    "total_exposure_time": null,
    "seccolumn": 10
  },
  "fits": [],
  "estimated_volume_method": null,
  "pddf_software": "ATSAS GNOM",
  "pddf_software_version": "5.0",
  "i0_calibration_standard": null,
  "description": null,
  "experiment_description": null,
  "tags": [],
  "intensity_unit": "1/cm",
  "experimental_mw": 27.4,
  "experimental_mw_error": null,
  "guinier_i0_mw": null,
  "guinier_i0_mw_error": null,
  "porod_mw": 22.5,
  "porod_mw_error": null,
  "pddf_i0": 0.1177,
  "pddf_i0_error": null,
  "guinier_i0": 0.117365,
  "guinier_i0_error": null,
  "pddf_rg": 2.19,
  "pddf_rg_error": null,
  "guinier_rg": 2.15,
  "guinier_rg_error": 0.024,
  "pddf_dmax": 8.7,
  "pddf_dmax_error": null,
  "porod_volume": 36.0,
  "porod_volume_error": null,
  "estimated_volume": null,
  "estimated_volume_error": null,
  "guinier_point_first": 16,
  "guinier_point_last": 107,
  "pddf_point_first": null,
  "pddf_point_last": null,
  "i0_calibration_standard_data": null,
  "intensities_log_log_plot": "SASDXE6_datloglog_img.png",
  "symmetry": null,
  "last_modified": "2026-06-01T13:55:24.260773+02:00",
  "bragg_peak": []
}