{
  "code": "SASDDK7",
  "status": "Published",
  "type_of_curve": "Single concentration",
  "angular_unit": "1/nm",
  "project": {
    "title": "Biophysical insights from a single chain camelid antibody directed against the Disrupted-in-Schizophrenia 1 protein.",
    "publication": {
      "title": "Biophysical insights from a single chain camelid antibody directed against the Disrupted-in-Schizophrenia 1 protein.",
      "author_list": "Yerabham ASK, Müller-Schiffmann A, Ziehm T, Stadler A, Köber S, Indurkhya X, Marreiros R, Trossbach SV, Bradshaw NJ, Prikulis I, Willbold D, Weiergräber OH, Korth C",
      "journal": "PLoS One",
      "doi": "10.1371/journal.pone.0191162",
      "pmid": "29324815",
      "published_date": "2018"
    },
    "status": "released",
    "submitted_date": "2018-05-16",
    "released_date": "2018-06-05"
  },
  "pddf_data": "https://www.sasbdb.org/media/p_of_R_files/SASDDK7.out",
  "intensities_data": "https://www.sasbdb.org/media/intensities_files/SASDDK7.dat",
  "intensities_log_plot": "https://www.sasbdb.org/media/intensities_files/scattering_plots/SASDDK7_dat_img.png",
  "intensities_kratky_plot": "https://www.sasbdb.org/media/intensities_files/scattering_plots/SASDDK7_kratky_img.png",
  "pddf_plot": "https://www.sasbdb.org/media/p_of_R_files/pofr_images/SASDDK7_pofr_img.png",
  "intensities_guinier_plot": "https://www.sasbdb.org/media/intensities_files/scattering_plots/SASDDK7_guinier_img.png",
  "sascif_data": "https://www.sasbdb.org/media/sascif/sascif_files/SASDDK7.sascif",
  "experiment": {
    "instrument": {
      "detector": {
        "type": "Custom-built",
        "name": "Pilatus 1M-W",
        "resolution": 0.172
      },
      "name": "PETRA III",
      "city": "DESY; Hamburg",
      "country": "Germany",
      "beamline_name": "EMBL P12",
      "beam_geometry": "Point",
      "type_of_source": "X-ray synchrotron",
      "point_source": null,
      "line_collimation": null,
      "sample_path_length": null,
      "line_collimation_slitlength": null,
      "line_collimation_integrationwidth": null,
      "xray_energy": null,
      "beam_profile_ah": null,
      "beam_profile_al": null
    },
    "sample": {
      "molecule": [
        {
          "long_name": "Disrupted- in-schizophrenia 1 (DISC1 12D2) 691-836",
          "short_name": "DISC1 12D2",
          "sequence": "MGHHHHHHDYDIPTTENLYFQGWEADLEACRLLIQSLQLQEARGSLSVEDE\r\nRQMDDLEGAAPPIPPRLHSEDKRKTPLKVLEEWKTHLIPSLHCAGGEQKEESYILSAELG\r\nEKCEDIGKKLLYLEDQLHTAIHSHDEDLIQSLRRELQMVKETLQAMILQLQPAKEAGSG",
          "organism": null,
          "uniprot_code": "Q9NRI5",
          "uniprot_range_first": 691,
          "uniprot_range_last": 836,
          "oligomerization": "monomer",
          "molecular_type": "protein",
          "uniprot_sequence": "MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA\nVGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI\nQLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA\nELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ\nSPQEMGAKAASLDGPHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG\nSSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRLKLQKL\nQEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGA\nTQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLE\nAKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPP\nETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNH\nFWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAY\nETSVKENTMKYMETLKNKLCSCKCPLLGKVWEADLEACRLLIQSLQLQEARGSLSVEDER\nQMDDLEGAAPPIPPRLHSEDKRKTPLKVLEEWKTHLIPSLHCAGGEQKEESYILSAELGE\nKCEDIGKKLLYLEDQLHTAIHSHDEDLIQSLRRELQMVKETLQAMILQLQPAKEAGEREA\nAASCMTAGVHEAQA",
          "mw": 19.426,
          "total_mw": 19.426,
          "number_molecules": 1,
          "complex_state": false,
          "deuteration": null,
          "molecule_source": "biological",
          "molecule_description": null
        }
      ],
      "buffer": {
        "name": "25 mM Tris-HCl, 150 mM NaCl, 1mM DTT",
        "concentration_unit": null,
        "comment": null,
        "additive": null,
        "concentration": null,
        "pka": null,
        "ph": 7.4,
        "deuteration": null
      },
      "purity_method": null,
      "name": "Disrupted-in-Schizophrenia 1 protein (DISC1 12d2)",
      "ext_coefficient": null,
      "contrast": null,
      "specific_vol": null,
      "dry_vol": null,
      "absorbption": null,
      "deuteration": null,
      "mixture": null
    },
    "contributor": [
      {
        "affiliation": [
          {
            "short_name": null,
            "address": "Germany",
            "full_name": "Forschungszentrum Jülich",
            "webpage": "https://www.fz-juelich.de"
          }
        ],
        "contributor_name": "Andreas",
        "contributor_surname": "Stadler",
        "orcid": null
      }
    ],
    "concentration_method": null,
    "concentration_unit": null,
    "date": "2015-10-01",
    "storage_temperature": 20.0,
    "cell_temperature": 20.0,
    "exposure_time": 0.095,
    "number_of_frames": 20,
    "wavelength": 0.123987,
    "sample_detector_distance": 3.0,
    "concentration_min": null,
    "concentration_max": 2.8,
    "sample_volume": null,
    "flow_rate": null,
    "s_min": 0.049,
    "s_max": 4.81,
    "total_exposure_time": null,
    "seccolumn": null
  },
  "fits": [
    {
      "models": [
        {
          "model_plot": "https://www.sasbdb.org/media/pdb_file/images/SASDDK7_fit1_model1_img.png",
          "software": "GASBOR",
          "pdb_link": [],
          "model_title": null,
          "type_of_model": "dummy",
          "software_version": null,
          "model_data": "https://www.sasbdb.org/media/pdb_file/SASDDK7_fit1_model1.pdb",
          "model_mw": null,
          "bead_radius": 1.9,
          "log": null,
          "symmetry": null,
          "comment": null,
          "user": 317
        },
        {
          "model_plot": "https://www.sasbdb.org/media/pdb_file/images/SASDDK7_fit1_model2_img.png",
          "software": "GASBOR",
          "pdb_link": [],
          "model_title": null,
          "type_of_model": "dummy",
          "software_version": "2.8.3",
          "model_data": "https://www.sasbdb.org/media/pdb_file/SASDDK7_fit1_model2.pdb",
          "model_mw": 14.328,
          "bead_radius": 2.5,
          "log": null,
          "symmetry": null,
          "comment": null,
          "user": 317
        }
      ],
      "fit_unit": "1/A",
      "fit_plot": "https://www.sasbdb.org/media/fitting_files/scattering_plots/disc_gasbor_18_NY0Oi5w_mRhYFU9_fit_img.png",
      "software": "GASBOR",
      "chi_square_value": 5.7596,
      "p_value": 0.0,
      "fit_residual_plot": "disc_gasbor_18_NY0Oi5w_mRhYFU9_fitresiduals_img.png",
      "fit_data": "https://www.sasbdb.org/media/fitting_files/SASDDK7_fit1.fir",
      "fit_log": "https://www.sasbdb.org/media/fitting_files/log_files/disc_gasbor_18.log",
      "software_version": null,
      "description": null
    },
    {
      "models": [
        {
          "model_plot": "https://www.sasbdb.org/media/pdb_file/images/SASDDK7_fit2_model1_img.png",
          "software": "DAMMIF",
          "pdb_link": [],
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          "type_of_model": "dummy",
          "software_version": "2.8.3",
          "model_data": "https://www.sasbdb.org/media/pdb_file/SASDDK7_fit2_model1.pdb",
          "model_mw": 28.95,
          "bead_radius": 2.0,
          "log": null,
          "symmetry": null,
          "comment": null,
          "user": 317
        },
        {
          "model_plot": "https://www.sasbdb.org/media/pdb_file/images/SASDDK7_fit2_model2_img.png",
          "software": "DAMMIF",
          "pdb_link": [],
          "model_title": null,
          "type_of_model": "dummy",
          "software_version": "2.8.3",
          "model_data": "https://www.sasbdb.org/media/pdb_file/SASDDK7_fit2_model2.pdb",
          "model_mw": 28.878,
          "bead_radius": 2.5,
          "log": null,
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          "comment": null,
          "user": 317
        }
      ],
      "fit_unit": "1/A",
      "fit_plot": "https://www.sasbdb.org/media/fitting_files/scattering_plots/SASDDK7_fit2_fit_img.png",
      "software": "DAMMIF",
      "chi_square_value": 1.170724,
      "p_value": 0.000321,
      "fit_residual_plot": "SASDDK7_fit2_fitresiduals_img.png",
      "fit_data": "https://www.sasbdb.org/media/fitting_files/SASDDK7_fit2.fir",
      "fit_log": null,
      "software_version": "2.8.3",
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    }
  ],
  "estimated_volume_method": null,
  "pddf_software": "ATSAS GNOM",
  "pddf_software_version": "5.0",
  "i0_calibration_standard": null,
  "description": null,
  "experiment_description": "Synchrotron SAXS data from solutions of the disrupted-in-Schizophrenia 1 protein (DISC1 12d2) in 25 mM Tris-HCl, 150 mM NaCl, 1mM DTT, pH 7.4 were collected on the EMBL P12 beam line at the PETRA III storage ring (Hamburg, Germany) using a Pilatus 1M-W detector at a sample-detector distance of 3 m and at a wavelength of λ = 0.123987 nm (l(s) vs s, where s = 4πsinθ/λ, and 2θ is the scattering angle). One solute concentration of 2.80 mg/ml was measured at 20°C. 20 successive 0.095 second frames were collected. The data were normalized to the intensity of the transmitted beam and radially averaged; the scattering of the solvent-blank was subtracted.",
  "tags": [],
  "intensity_unit": "arbitrary",
  "experimental_mw": 17.31,
  "experimental_mw_error": null,
  "guinier_i0_mw": 17.31,
  "guinier_i0_mw_error": null,
  "porod_mw": 24.1,
  "porod_mw_error": null,
  "pddf_i0": 444.6,
  "pddf_i0_error": null,
  "guinier_i0": 461.76,
  "guinier_i0_error": 1.15,
  "pddf_rg": 2.512,
  "pddf_rg_error": null,
  "guinier_rg": 2.64,
  "guinier_rg_error": 0.1,
  "pddf_dmax": 7.26,
  "pddf_dmax_error": null,
  "porod_volume": 40.9,
  "porod_volume_error": null,
  "estimated_volume": null,
  "estimated_volume_error": null,
  "guinier_point_first": 14,
  "guinier_point_last": 168,
  "pddf_point_first": null,
  "pddf_point_last": null,
  "i0_calibration_standard_data": null,
  "intensities_log_log_plot": "SASDDK7_datloglog_img.png",
  "symmetry": null,
  "last_modified": "2023-06-21T07:56:18.120449+02:00",
  "bragg_peak": []
}