{ "code": "SASDYX3", "status": "Published", "type_of_curve": "Single concentration", "angular_unit": "1/A", "project": { "title": "Modulation of Homer1 EVH1 domain internal dynamics by putative autism-associated mutations.", "publication": { "title": "Modulation of Homer1 EVH1 domain internal dynamics by putative autism-associated mutations.", "author_list": "Farkas F, Maruzs B, Kálmán ZE, Klumpler T, Batta G, Péterfia B, Gáspári Z", "journal": "FEBS Lett", "doi": "10.1002/1873-3468.70369", "pmid": "42206738", "published_date": "2026 May 28" }, "status": "released", "submitted_date": "2025-12-10", "released_date": "2026-06-01" }, "pddf_data": "https://www.sasbdb.org/media/p_of_R_files/SASDYX3.out", "intensities_data": "https://www.sasbdb.org/media/intensities_files/SASDYX3.dat", "intensities_log_plot": "https://www.sasbdb.org/media/intensities_files/scattering_plots/SASDYX3_dat_img.png", "intensities_kratky_plot": "https://www.sasbdb.org/media/intensities_files/scattering_plots/SASDYX3_kratky_img.png", "pddf_plot": "https://www.sasbdb.org/media/p_of_R_files/pofr_images/SASDYX3_pofr_img.png", "intensities_guinier_plot": "https://www.sasbdb.org/media/intensities_files/scattering_plots/SASDYX3_guinier_img.png", "sascif_data": "https://www.sasbdb.org/media/sascif/sascif_files/SASDYX3.sascif", "experiment": { "instrument": { "detector": { "type": "Hybrid Photon Counting (HPC) X-ray detector", "name": "Rigaku HyPix-3000", "resolution": 100.0 }, "name": "CEITEC", "city": "Brno", "country": "Czech Republic", "beamline_name": "Rigaku BioSAXS-2000", "beam_geometry": null, "type_of_source": "X-ray in house", "point_source": null, "line_collimation": null, "sample_path_length": null, "line_collimation_slitlength": null, "line_collimation_integrationwidth": null, "xray_energy": null, "beam_profile_ah": null, "beam_profile_al": null }, "sample": { "molecule": [ { "long_name": "Point mutant S97L of EVH1 domain of Homer protein homolog 1 from mouse monomer", "short_name": "EVH1 Homer S97L", "sequence": "GSHMGEQPIFSTRAHVFQIDPNTKKNWVPTSKHAVTVSYFYDSTRNVYRIISLDGSKAIINSTITPNMTFTKTSQKFGQWADSRANTVYGLGFSSEHHLLKFAEKFQEFKEAARLAKEKSQ", "organism": "Mus musculus", "uniprot_code": "Q9Z2Y3", "uniprot_range_first": 3, "uniprot_range_last": 121, "oligomerization": "monomer", "molecular_type": "protein", "uniprot_sequence": "MGEQPIFSTRAHVFQIDPNTKKNWVPTSKHAVTVSYFYDSTRNVYRIISLDGSKAIINST\nITPNMTFTKTSQKFGQWADSRANTVYGLGFSSEHHLSKFAEKFQEFKEAARLAKEKSQEK\nMELTSTPSQESAGGDLQSPLTPESINGTDDERTPDVTQNSEPRAEPTQNALPFPHSAGDR\nTQALSHASSAISKHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKR\nVTELECVSSQANAVHSHKTELNQTVQELEETLKVKEEEIERLKQEIDNARELQEQRDSLT\nQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAFRSNLKTLLEILDGKIFELTELRDNLA\nKLLECS", "mw": 13.76, "total_mw": 13.6, "number_molecules": 1, "complex_state": false, "deuteration": null, "molecule_source": "synthetic", "molecule_description": "" } ], "buffer": { "name": "20mM NaCl, 50 mM NaPi, 0.02% of sodium-azide", "concentration_unit": null, "comment": null, "additive": null, "concentration": null, "pka": null, "ph": 7.4, "deuteration": null }, "purity_method": null, "name": "Point mutant S97L of EVH1 domain of Homer protein homolog 1 from mouse monomer", "ext_coefficient": null, "contrast": null, "specific_vol": null, "dry_vol": null, "absorbption": null, "deuteration": null, "mixture": null }, "contributor": [ { "affiliation": [ { "short_name": null, "address": null, "full_name": "CEITEC - Central European Institute of Technology, Masaryk University", "webpage": "https://www.ceitec.eu/" } ], "contributor_name": "Tomas", "contributor_surname": "Klumpler", "orcid": null } ], "concentration_method": null, "concentration_unit": null, "date": "2023-11-08", "storage_temperature": 4.0, "cell_temperature": 25.0, "exposure_time": 600.0, "number_of_frames": 10, "wavelength": 0.154, "sample_detector_distance": 0.48, "concentration_min": null, "concentration_max": 4.0, "sample_volume": null, "flow_rate": null, "s_min": 0.034, "s_max": 6.442, "total_exposure_time": null, "seccolumn": null }, "fits": [ { "models": [ { "model_plot": "https://www.sasbdb.org/media/pdb_file/images/SASDYX3_fit1_model1_img.png", "software": "GROMACS", "pdb_link": [], "model_title": null, "type_of_model": "atomic", "software_version": "2023.2", "model_data": "https://www.sasbdb.org/media/pdb_file/SASDYX3_fit1_model1.pdb", "model_mw": 13.77, "bead_radius": null, "log": null, "symmetry": null, "comment": null, "user": 195 } ], "fit_unit": "1/A", "fit_plot": "https://www.sasbdb.org/media/fitting_files/scattering_plots/SASDYX3_fit1_fixed_fit_img.png", "software": "Pepsi-SAXS", "chi_square_value": 1.1003, "p_value": 0.4393, "fit_residual_plot": "SASDYX3_fit1_fitresiduals_img.png", "fit_data": "https://www.sasbdb.org/media/fitting_files/SASDYX3_fit1.fit", "fit_log": "https://www.sasbdb.org/media/fitting_files/log_files/s97l_model1_bmrb-S97L_25deg_4mg_20231108_subtr.log", "software_version": "3.0", "description": "" } ], "estimated_volume_method": null, "pddf_software": "ATSAS GNOM", "pddf_software_version": null, "i0_calibration_standard": null, "description": null, "experiment_description": null, "tags": [], "intensity_unit": "arbitrary", "experimental_mw": 11.25, "experimental_mw_error": null, "guinier_i0_mw": null, "guinier_i0_mw_error": null, "porod_mw": 14.28, "porod_mw_error": null, "pddf_i0": 0.7517, "pddf_i0_error": null, "guinier_i0": 0.774633, "guinier_i0_error": null, "pddf_rg": 1.58, "pddf_rg_error": null, "guinier_rg": 1.665, "guinier_rg_error": 0.13, "pddf_dmax": 4.25, "pddf_dmax_error": null, "porod_volume": 22.85, "porod_volume_error": null, "estimated_volume": null, "estimated_volume_error": null, "guinier_point_first": 16, "guinier_point_last": 91, "pddf_point_first": null, "pddf_point_last": null, "i0_calibration_standard_data": null, "intensities_log_log_plot": "SASDYX3_datloglog_img.png", "symmetry": null, "last_modified": "2026-06-01T15:03:22.647475+02:00", "bragg_peak": [] }