{
  "code": "SASDYY5",
  "status": "Published",
  "type_of_curve": "Merged",
  "angular_unit": "1/A",
  "project": {
    "title": "An intrinsically disordered region mediates RNA-binding selectivity and cellular activities of LARP6.",
    "publication": {
      "title": "An intrinsically disordered region mediates RNA-binding selectivity and cellular activities of LARP6.",
      "author_list": "Capraro F, Abis G, Incocciati A, Simpson PJ, Karimzadeh M, Masino L, Barley A, Bui TTT, Kelly G, Goodarzi H, Conte MR, Mardakheh FK",
      "journal": "Nat Commun",
      "doi": "10.1038/s41467-026-69789-z",
      "pmid": "41714637",
      "published_date": "2026 Feb 19"
    },
    "status": "released",
    "submitted_date": "2026-01-20",
    "released_date": "2026-02-21"
  },
  "pddf_data": "https://www.sasbdb.org/media/p_of_R_files/SASDYY5.dat",
  "intensities_data": "https://www.sasbdb.org/media/intensities_files/SASDYY5.txt",
  "intensities_log_plot": "https://www.sasbdb.org/media/intensities_files/scattering_plots/SASDYY5_dat_img.png",
  "intensities_kratky_plot": "https://www.sasbdb.org/media/intensities_files/scattering_plots/SASDYY5_kratky_img.png",
  "pddf_plot": "https://www.sasbdb.org/media/p_of_R_files/pofr_images/SASDYY5_pofr_img.png",
  "intensities_guinier_plot": "https://www.sasbdb.org/media/intensities_files/scattering_plots/SASDYY5_guinier_img.png",
  "sascif_data": "https://www.sasbdb.org/media/sascif/sascif_files/SASDYY5.sascif",
  "experiment": {
    "instrument": {
      "detector": {
        "type": null,
        "name": "Eiger 4M",
        "resolution": 75.0
      },
      "name": "Diamond Light Source",
      "city": "Didcot",
      "country": "UK",
      "beamline_name": "B21",
      "beam_geometry": null,
      "type_of_source": "X-ray synchrotron",
      "point_source": null,
      "line_collimation": null,
      "sample_path_length": null,
      "line_collimation_slitlength": null,
      "line_collimation_integrationwidth": null,
      "xray_energy": null,
      "beam_profile_ah": null,
      "beam_profile_al": null
    },
    "sample": {
      "molecule": [
        {
          "long_name": "La-related protein 6",
          "short_name": "LARP6",
          "sequence": "MAQSGGEARPGPKTAVQIRVAIQEAEDVDELEDEEEGAETRGAGDPARYLSPGWGSASEEEPSRGHSGTTASGGENEREDLEQ",
          "organism": "Homo sapiens",
          "uniprot_code": "Q9BRS8",
          "uniprot_range_first": 1,
          "uniprot_range_last": 83,
          "oligomerization": "monomer",
          "molecular_type": "protein",
          "uniprot_sequence": "MAQSGGEARPGPKTAVQIRVAIQEAEDVDELEDEEEGAETRGAGDPARYLSPGWGSASEE\nEPSRGHSGTTASGGENEREDLEQEWKPPDEELIKKLVDQIEFYFSDENLEKDAFLLKHVR\nRNKLGYVSVKLLTSFKKVKHLTRDWRTTAHALKYSVVLELNEDHRKVRRTTPVPLFPNEN\nLPSKMLLVYDLYLSPKLWALATPQKNGRVQEKVMEHLLKLFGTFGVISSVRILKPGRELP\nPDIRRISSRYSQVGTQECAIVEFEEVEAAIKAHEFMITESQGKENMKAVLIGMKPPKKKP\nAKDKNHDEEPTASIHLNKSLNKRVEELQYMGDESSANSSSDPESNPTSPMAGRRHAATNK\nLSPSGHQNLFLSPNASPCTSPWSSPLAQRKGVSRKSPLAEEGRLNCSTSPEIFRKCMDYS\nSDSSVTPSGSPWVRRRRQAEMGTQEKSPGTSPLLSRKMQTADGLPVGVLRLPRGPDNTRG\nFHGHERSRACV",
          "mw": 8.727,
          "total_mw": 8.727,
          "number_molecules": 0,
          "complex_state": false,
          "deuteration": null,
          "molecule_source": "biological",
          "molecule_description": "LARP6 N-terminal region (NTR) intrinsically disordered tail"
        }
      ],
      "buffer": {
        "name": "25 mM Tris-HCl, 100 mM KCl, 5 mM MgCl2, 1 mM DTT",
        "concentration_unit": null,
        "comment": "SEC-SAXS buffer",
        "additive": null,
        "concentration": null,
        "pka": null,
        "ph": 7.5,
        "deuteration": null
      },
      "purity_method": null,
      "name": "La-related protein 6 (LARP6) N-terminal region (NTR) apo",
      "ext_coefficient": null,
      "contrast": null,
      "specific_vol": null,
      "dry_vol": null,
      "absorbption": null,
      "deuteration": null,
      "mixture": null
    },
    "contributor": [
      {
        "affiliation": [
          {
            "short_name": null,
            "address": "London, UK",
            "full_name": "King's College London",
            "webpage": "https://www.kcl.ac.uk"
          }
        ],
        "contributor_name": "Giancarlo",
        "contributor_surname": "Abis",
        "orcid": ""
      }
    ],
    "concentration_method": null,
    "concentration_unit": null,
    "date": "2024-10-01",
    "storage_temperature": 4.0,
    "cell_temperature": 15.0,
    "exposure_time": 0.35,
    "number_of_frames": 600,
    "wavelength": 0.09537,
    "sample_detector_distance": 3.6903,
    "concentration_min": 4.0,
    "concentration_max": 5.0,
    "sample_volume": null,
    "flow_rate": null,
    "s_min": 0.045,
    "s_max": 3.4,
    "total_exposure_time": null,
    "seccolumn": null
  },
  "fits": [],
  "estimated_volume_method": null,
  "pddf_software": "ScÅtter",
  "pddf_software_version": null,
  "i0_calibration_standard": null,
  "description": "LARP6 N-terminal region (NTR), an intrinsically disordered tail spanning residues 1-84.\r\nExperimental molecular weight was estimated by SEC-MALLS.",
  "experiment_description": null,
  "tags": [],
  "intensity_unit": "arbitrary",
  "experimental_mw": 11.2,
  "experimental_mw_error": null,
  "guinier_i0_mw": null,
  "guinier_i0_mw_error": null,
  "porod_mw": 13.0,
  "porod_mw_error": null,
  "pddf_i0": 0.07635215,
  "pddf_i0_error": null,
  "guinier_i0": 0.0127297,
  "guinier_i0_error": null,
  "pddf_rg": 2.73,
  "pddf_rg_error": null,
  "guinier_rg": 2.709,
  "guinier_rg_error": 0.056,
  "pddf_dmax": 9.4,
  "pddf_dmax_error": null,
  "porod_volume": 21.0,
  "porod_volume_error": null,
  "estimated_volume": null,
  "estimated_volume_error": null,
  "guinier_point_first": 40,
  "guinier_point_last": 375,
  "pddf_point_first": null,
  "pddf_point_last": null,
  "i0_calibration_standard_data": null,
  "intensities_log_log_plot": "SASDYY5_datloglog_img.png",
  "symmetry": null,
  "last_modified": "2026-02-21T16:07:53.696587+01:00",
  "bragg_peak": []
}