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11ou

Omi32 germline Fab in complex with LC-Kappa VHH

Method: ELECTRON MICROSCOPY D_max: 85.3 Å Quality: EXCELLENT

SAXS Profile

P(r) Distribution

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1. Structure Basics

entry_id	11ou
deposition_date	2026-03-06
title	Omi32 germline Fab in complex with LC-Kappa VHH
keywords	antibody, fab, germline, ancestor, IMMUNE SYSTEM; IMMUNE SYSTEM
method	ELECTRON MICROSCOPY

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Download Data

SAXS curve (.dat) P(r) distribution (.pr.out) Structure (CIF)

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2. SAXS Parameters (CRYSOL)

rg_guinier	27.52 Å
rg_electron	26.55 Å
i0	60277100.00
molecular_weight	59069.0 kDa
excluded_volume	73284 Å³
envelope_volume	92309 Å³
shell_volume	28989 Å³
envelope_diameter	91.4 Å
shell_rg	33.80 Å
envelope_rg	26.28 Å
shape_rg	26.53 Å
total_rg	27.39 Å
total_atoms	4163
n_residues	549
n_harmonics	20
q_range	— – 0.5000 Å⁻¹
n_points	101
shell_type	directional
solvent_density	0.3340 e/Å³
contrast_shell	0.0300 e/Å³
crysol_version	4.1.3

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3. P(r) Analysis (GNOM)

dmax	85.3 Å
rg_real	27.41 Å
rg_real_error	0.52 Å
i0_real	6.0280e+07
i0_real_error	8.0170e+05
rg_reciprocal	27.45 Å
i0_reciprocal	60280000.0000
total_estimate	0.9106
solution_quality	EXCELLENT a EXCELLENT solution
n_peaks	2
r_peak_primary	36.8 Å
skewness	0.153
kurtosis	-0.581
angular_range	— – 0.2900 Å⁻¹
current_alpha	0.0000
highest_alpha	12960000.0000
n_real_points	59
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.962; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 1.000; Smooth: 0.949

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4. Crystallography & Experiment

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5. Entities & Polymer Info (3)

Entity 1 polymer

description	LC-Kappa VHH
formula_weight	13162.4 kDa
src_method	man
entity_count	1

Polymer

type	polypeptide(L)
strand_id	K
atom_count	4163

EVQLQESGGGLVQPGGSLRLSCAASGRTISRYAMSWFRQAPGKEREFVATARRSGDGAFYADSVQGRFTVSRDDAKNTVYLQMNSLKPEDTAVYYCAIDSDTFYSGSYDYWGQGTQVTVS

Source

organism	Lama glama
ncbi_taxonomy_id	9844
host_organism	Saccharomyces cerevisiae

Entity 2 polymer

description	Omi32 germline light chain
formula_weight	23227.8 kDa
src_method	man
entity_count	1

Polymer

type	polypeptide(L)
strand_id	L

IVLTQSPGTLSLSPGERATLSCRASQSVSSSYLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSPRLTFGGGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE

Source

organism	Homo sapiens
ncbi_taxonomy_id	9606
host_organism	Homo sapiens

Entity 3 polymer

description	Omi32 germline heavy chain
formula_weight	23379.2 kDa
src_method	man
entity_count	1

Polymer

type	polypeptide(L)
strand_id	H

QVQLVESGGGVVQPGRSLRLSCAASGFTFSSYGMHWVRQAPGKGLEWVAVIWYDGSNKYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARDTAPPDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC

Source

organism	Homo sapiens
ncbi_taxonomy_id	9606
host_organism	Homo sapiens

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6. Citations (1)

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length_a	1.000 Å
length_b	1.000 Å
length_c	1.000 Å
angle_alpha	90.00 °
angle_beta	90.00 °
angle_gamma	90.00 °
z_pdb	—

space_group	P 1
int_tables_number	1
crystal_system	—

resolution	3.200 Å
resolution_low	— Å
r_factor	—
r_work	—
r_free	—

resolution	3.20 Å
resolution_method	—
num_particles	73477

fit	/app/data/saxs_computation/1o/11ou/11ou.fit
pddf	/app/data/pr_computation/1o/11ou/11ou.pr.out
profile	/app/data/saxs_computation/1o/11ou/11ou.dat

Omi32 germline Fab in complex with LC-Kappa VHH

SAXS Profile

P(r) Distribution

1. Structure Basics

Download Data

2. SAXS Parameters (CRYSOL)

3. P(r) Analysis (GNOM)

4. Crystallography & Experiment

Unit Cell

Symmetry

Refinement

EM 3D

5. Entities & Polymer Info (3)

Entity 1 polymer

Polymer

Source

Entity 2 polymer

Polymer

Source

Entity 3 polymer

Polymer

Source

6. Citations (1)

7. Files & Curves (10)

Files (7)

Curves (3)