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12fc

Crystal structure of unliganded Fab 7118

Method: X-RAY DIFFRACTION D_max: 80.8 Å Quality: EXCELLENT

SAXS Profile

P(r) Distribution

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1. Structure Basics

entry_id	12fc
deposition_date	2026-04-01
last_revision	2026-05-27
title	Crystal structure of unliganded Fab 7118
keywords	Antibody for Malaria, IMMUNE SYSTEM; IMMUNE SYSTEM
method	X-RAY DIFFRACTION

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Download Data

SAXS curve (.dat) P(r) distribution (.pr.out) Structure (CIF)

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2. SAXS Parameters (CRYSOL)

rg_guinier	24.93 Å
rg_electron	23.98 Å
i0	36866100.00
molecular_weight	46755.0 kDa
excluded_volume	58415 Å³
envelope_volume	71576 Å³
shell_volume	25146 Å³
envelope_diameter	84.6 Å
shell_rg	30.83 Å
envelope_rg	23.75 Å
shape_rg	23.97 Å
total_rg	24.82 Å
total_atoms	3293
n_residues	416
n_harmonics	20
q_range	— – 0.5000 Å⁻¹
n_points	101
shell_type	directional
solvent_density	0.3340 e/Å³
contrast_shell	0.0300 e/Å³
crysol_version	4.1.3

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3. P(r) Analysis (GNOM)

dmax	80.8 Å
rg_real	24.89 Å
rg_real_error	0.50 Å
i0_real	3.6870e+07
i0_real_error	5.0900e+05
rg_reciprocal	24.90 Å
i0_reciprocal	36870000.0000
total_estimate	0.9021
solution_quality	EXCELLENT a EXCELLENT solution
n_peaks	2
r_peak_primary	29.5 Å
skewness	0.282
kurtosis	-0.432
angular_range	— – 0.3200 Å⁻¹
current_alpha	0.0000
highest_alpha	8575000.0000
n_real_points	64
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.918; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.979; Smooth: 0.991

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4. Crystallography & Experiment

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5. Entities & Polymer Info (3)

Entity 1 polymer

description	Heavy Chain of Fab 7118
formula_weight	24608.6 kDa
src_method	man
entity_count	1

Polymer

type	polypeptide(L)
strand_id	A
atom_count	3402

EVQVVESGGGVVQPGRSLRLSCTASGFTFGDYAMSWFRQAPGKGLEWVGFIRSEANGGAPEYAASVKGRFTISRDDFKSIAYLQMNSLKTEDTAAYYCTRVRTNDFRDMDVWGKGTTVAVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHLC

Source

organism	Homo sapiens
ncbi_taxonomy_id	9606
host_organism	Cricetulus griseus

Entity 2 polymer

description	Light Chain of Fab 7188
formula_weight	24281.2 kDa
src_method	man
entity_count	1

Polymer

type	polypeptide(L)
strand_id	B

DIVMTQTPLSLSVTPGQPASISCKSTESLLHRDGKTYLYWYLQKPGQPPQLLIYEVSNRFSGVPDRFSGSGSVTDFTLKISRVEAEDIGVYYCMQTIDLPWTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC

Source

organism	Homo sapiens
ncbi_taxonomy_id	9606
host_organism	Cricetulus griseus

Entity 3 water

description	water
formula_weight	18.0 kDa
src_method	nat
entity_count	109

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6. Citations (1)

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length_a	44.665 Å
length_b	73.202 Å
length_c	150.503 Å
angle_alpha	90.00 °
angle_beta	90.00 °
angle_gamma	90.00 °
z_pdb	4

space_group	P 21 21 21
int_tables_number	19
crystal_system	—

resolution	2.290 Å
resolution_low	41.380 Å
r_factor	0.2234
r_work	0.2180
r_free	0.2778

fit	/app/data/saxs_computation/2f/12fc/12fc.fit
pddf	/app/data/pr_computation/2f/12fc/12fc.pr.out
profile	/app/data/saxs_computation/2f/12fc/12fc.dat

Crystal structure of unliganded Fab 7118

SAXS Profile

P(r) Distribution

1. Structure Basics

Download Data

2. SAXS Parameters (CRYSOL)

3. P(r) Analysis (GNOM)

4. Crystallography & Experiment

Unit Cell

Symmetry

Refinement

Diffraction

5. Entities & Polymer Info (3)

Entity 1 polymer

Polymer

Source

Entity 2 polymer

Polymer

Source

Entity 3 water

6. Citations (1)

7. Files & Curves (10)

Files (7)

Curves (3)