12kl

SSNMR Structure of Anti-necroptosis Viral:Human Functional Hetero-amyloid M45:RIPK3

Method: SOLID-STATE NMR
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Receptor-interacting serine/threonine-protein kinase 3

Homo sapiens

UniProt Q9Y572

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 8 Ribonucleoside-diphosphate reductase large subunit-like protein × 4 (H2A2P4) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RIPK3_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A; PDBConstruct 3–133; UniProt 388–518 Author chain C; PDBConstruct 3–133; UniProt 388–518 Author chain E; PDBConstruct 3–133; UniProt 388–518 Author chain G; PDBConstruct 3–133; UniProt 388–518

Ribonucleoside-diphosphate reductase large subunit-like protein

Murid betaherpesvirus 1

UniProt H2A2P4

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 8 Receptor-interacting serine/threonine-protein kinase 3 × 4 (Q9Y572) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name H2A2P4_MUHV1
Isoform —
PDB entities 2
Chains and sequence ranges Author chain B; PDBConstruct 3–92; UniProt 1–90 Author chain D; PDBConstruct 3–92; UniProt 1–90 Author chain F; PDBConstruct 3–92; UniProt 1–90 Author chain H; PDBConstruct 3–92; UniProt 1–90

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id12kl
Deposition date deposition_date2026-04-09
Structure title titleSSNMR Structure of Anti-necroptosis Viral:Human Functional Hetero-amyloid M45:RIPK3
Keywords keywordshetero-amyloid, necroptosis, MCMV, RIPK3, PROTEIN FIBRIL; PROTEIN FIBRIL
Experimental Method methodSOLID-STATE NMR
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

12kl__assembly_1__model_6

Assembly 1 · Model 6 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

12kl__assembly_1__model_6 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

12kl__assembly_1__model_6 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)18.58 Å
Rg (electron density)17.95 Å
Total Rg18.79 Å
Atom count3292
Residues220
Excluded volume29365 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 12kl__assembly_1__model_1 octameric (8) Success 4.1.3-1-20251215 (887e7ef) View Download
1 2 12kl__assembly_1__model_2 octameric (8) Success 4.1.3-1-20251215 (887e7ef) View Download
1 3 12kl__assembly_1__model_3 octameric (8) Success 4.1.3-1-20251215 (887e7ef) View Download
1 4 12kl__assembly_1__model_4 octameric (8) Success 4.1.3-1-20251215 (887e7ef) View Download
1 5 12kl__assembly_1__model_5 octameric (8) Success 4.1.3-1-20251215 (887e7ef) View Download
1 6 12kl__assembly_1__model_6 octameric (8) Success 4.1.3-1-20251215 (887e7ef) View Download
1 7 12kl__assembly_1__model_7 octameric (8) Success 4.1.3-1-20251215 (887e7ef) View Download
1 8 12kl__assembly_1__model_8 octameric (8) Success 4.1.3-1-20251215 (887e7ef) View Download
1 9 12kl__assembly_1__model_9 octameric (8) Success 4.1.3-1-20251215 (887e7ef) View Download
1 10 12kl__assembly_1__model_10 octameric (8) Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (2)

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7. Citations (1)