← Back to search

1ad9

IGG-FAB FRAGMENT OF ENGINEERED HUMAN MONOCLONAL ANTIBODY CTM01

Method: X-RAY DIFFRACTION D_max: 126.5 Å Quality: GOOD

SAXS Profile

P(r) Distribution

▼

1. Structure Basics

entry_id	1ad9
deposition_date	1997-02-24
title	IGG-FAB FRAGMENT OF ENGINEERED HUMAN MONOCLONAL ANTIBODY CTM01
keywords	IMMUNOGLOBULIN, FAB FRAGMENT; IMMUNOGLOBULIN
method	X-RAY DIFFRACTION

▼

Download Data

SAXS curve (.dat) P(r) distribution (.pr.out) Structure (CIF)

▼

2. SAXS Parameters (CRYSOL)

rg_guinier	38.88 Å
rg_electron	39.08 Å
i0	145574000.00
molecular_weight	95952.0 kDa
excluded_volume	119370 Å³
envelope_volume	163230 Å³
shell_volume	37765 Å³
envelope_diameter	134.8 Å
shell_rg	40.76 Å
envelope_rg	38.72 Å
shape_rg	39.05 Å
total_rg	39.29 Å
total_atoms	6745
n_residues	876
n_harmonics	20
q_range	— – 0.5000 Å⁻¹
n_points	101
shell_type	directional
solvent_density	0.3340 e/Å³
contrast_shell	0.0300 e/Å³
crysol_version	4.1.3

▼

3. P(r) Analysis (GNOM)

dmax	126.5 Å
rg_real	39.35 Å
rg_real_error	1.31 Å
i0_real	1.4560e+08
i0_real_error	2.7650e+06
rg_reciprocal	39.06 Å
i0_reciprocal	145500000.0000
total_estimate	0.8116
solution_quality	GOOD a GOOD solution
n_peaks	1
r_peak_primary	37.0 Å
skewness	0.510
kurtosis	-0.451
angular_range	— – 0.2050 Å⁻¹
current_alpha	0.0000
highest_alpha	11240000.0000
n_real_points	42
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.866; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.811; Smooth: 0.137

▶

4. Crystallography & Experiment

▶

5. Entities & Polymer Info (4)

Entity 1 polymer

description	IGG CTM01 FAB (LIGHT CHAIN)
formula_weight	24162.0 kDa
src_method	man
entity_count	2

Polymer

type	polypeptide(L)
strand_id	L,A
atom_count	6760

DIQMTQSPSTLSASVGDRVTITCRSSKSLLHSNGDTFLYWFQQKPGKAPKLLMYRMSNLASGVPSRFSGSGSGTEFTLTISSLQPDDFATYYCMQHLEYPFTFGQGTKVEVKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC

Source

organism	Homo sapiens
common_name	human
ncbi_taxonomy_id	9606
host_organism	Mus musculus

Entity 2 polymer

description	IGG CTM01 FAB (HEAVY CHAIN)
formula_weight	23809.6 kDa
src_method	man
entity_count	2

Polymer

type	polypeptide(L)
strand_id	H,B

EIQLVQSGAEVKKPGSSVKVSCKASGYTFTDYYINWMRQAPGQGLEWIGWIDPGSGNTKYNEKFKGRATLTVDTSTNTAYMELSSLRSEDTAFYFCAREKTTYYYAMDYWGQGTLVTVSSASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYTCNVDHKPSNTKVDKRVE

Source

organism	Homo sapiens
common_name	human
ncbi_taxonomy_id	9606
host_organism	Mus musculus

Entity 3 non-polymer

description	SULFATE ION
formula_weight	96.1 kDa
src_method	syn
entity_count	1

Entity 4 water

description	water
formula_weight	18.0 kDa
src_method	nat
entity_count	15

▶

6. Citations (1)

▶

length_a	81.390 Å
length_b	104.630 Å
length_c	119.380 Å
angle_alpha	90.00 °
angle_beta	90.00 °
angle_gamma	90.00 °
z_pdb	8

space_group	P 21 21 21
int_tables_number	19
crystal_system	—

resolution	2.800 Å
resolution_low	15.000 Å
r_factor	0.2330
r_work	0.2330
r_free	0.2840

fit	/app/data/saxs_computation/ad/1ad9/1ad9.fit
pddf	/app/data/pr_computation/ad/1ad9/1ad9.pr.out
profile	/app/data/saxs_computation/ad/1ad9/1ad9.dat

IGG-FAB FRAGMENT OF ENGINEERED HUMAN MONOCLONAL ANTIBODY CTM01

SAXS Profile

P(r) Distribution

1. Structure Basics

Download Data

2. SAXS Parameters (CRYSOL)

3. P(r) Analysis (GNOM)

4. Crystallography & Experiment

Unit Cell

Symmetry

Refinement

Diffraction

5. Entities & Polymer Info (4)

Entity 1 polymer

Polymer

Source

Entity 2 polymer

Polymer

Source

Entity 3 non-polymer

Entity 4 water

6. Citations (1)

7. Files & Curves (10)

Files (7)

Curves (3)