COMPARISON OF THE THREE-DIMENSIONAL STRUCTURES OF A HUMANIZED AND A CHIMERIC FAB OF AN ANTI-GAMMA-INTERFERON ANTIBODY

entry_id	1b2w
deposition_date	1998-12-01
title	COMPARISON OF THE THREE-DIMENSIONAL STRUCTURES OF A HUMANIZED AND A CHIMERIC FAB OF AN ANTI-GAMMA-INTERFERON ANTIBODY
keywords	ANTIBODY ENGINEERING, HUMANIZED AND CHIMERIC ANTIBODY, FAB, THREE-DIMENSIONAL STRYCTURE, GAMMA-INTERFERON, IMMUNE SYSTEM; IMMUNE SYSTEM
method	X-RAY DIFFRACTION

rg_guinier	25.69 Å
rg_electron	24.73 Å
i0	37868900.00
molecular_weight	47193.0 kDa
excluded_volume	58813 ų
envelope_volume	71822 ų
shell_volume	24399 ų
envelope_diameter	80.4 Å
shell_rg	31.79 Å
envelope_rg	24.27 Å
shape_rg	24.71 Å
total_rg	25.60 Å
total_atoms	3325
n_residues	433
n_harmonics	20
q_range	— – 0.5000 Å−1
n_points	101
shell_type	directional
solvent_density	0.3340 e/ų
contrast_shell	0.0300 e/ų
crysol_version	4.1.3

dmax	80.0 Å
rg_real	25.66 Å
rg_real_error	0.39 Å
i0_real	3.7870e+07
i0_real_error	5.4160e+05
rg_reciprocal	25.67 Å
i0_reciprocal	37870000.0000
total_estimate	0.9104
solution_quality	EXCELLENT a EXCELLENT solution
n_peaks	1
r_peak_primary	28.4 Å
skewness	0.239
kurtosis	-0.586
angular_range	— – 0.3100 Å−1
current_alpha	0.0002
highest_alpha	5841000.0000
n_real_points	63
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.968; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.992; Smooth: 0.936

Unit Cell

length_a	69.100 Å
length_b	74.600 Å
length_c	104.300 Å
angle_alpha	90.00 °
angle_beta	90.00 °
angle_gamma	90.00 °
z_pdb	4

Symmetry

space_group	P 21 21 21
int_tables_number	19
crystal_system	—

Refinement

resolution	2.900 Å
resolution_low	8.000 Å
r_factor	—
r_work	0.1880
r_free	0.3300

Diffraction

temperature

286.0 K

Files (7)

• pr_distribution /app/data/pr_computation/b2/1b2w/pr_distribution.json
• pr_output /app/data/pr_computation/b2/1b2w/1b2w.pr.out
• pr_plot /app/data/visualization/pr_computation/b2/1b2w/1b2w_pr_distribution.png
• saxs_curve_dat /app/data/saxs_computation/b2/1b2w/1b2w.dat
• saxs_fit /app/data/saxs_computation/b2/1b2w/1b2w.fit
• saxs_log /app/data/saxs_computation/b2/1b2w/1b2w.log
• saxs_plot /app/data/visualization/saxs_computation/b2/1b2w/1b2w_saxs_profile.png

Curves (3)

fit	/app/data/saxs_computation/b2/1b2w/1b2w.fit
pddf	/app/data/pr_computation/b2/1b2w/1b2w.pr.out
profile	/app/data/saxs_computation/b2/1b2w/1b2w.dat