1cya
NMR STUDIES OF (U-13C)CYCLOSPORIN A BOUND TO CYCLOPHILIN: BOUND CONFORMATION AND PORTIONS OF CYCLOSPORIN INVOLVED IN BINDING
SAXS Profile
P(r) Distribution
1. Structure Basics
| entry_id | 1cya |
| deposition_date | 1992-02-24 |
| title | NMR STUDIES OF (U-13C)CYCLOSPORIN A BOUND TO CYCLOPHILIN: BOUND CONFORMATION AND PORTIONS OF CYCLOSPORIN INVOLVED IN BINDING |
| keywords | IMMUNOSUPPRESSANT, CYCLOSPORIN A; IMMUNOSUPPRESSANT |
| method | SOLUTION NMR |
Download Data
2. SAXS Parameters (CRYSOL)
| rg_guinier | 7.68 Å |
| rg_electron | 6.24 Å |
| i0 | 29027.90 |
| molecular_weight | 1212.0 kDa |
| excluded_volume | 1779 ų |
| envelope_volume | 1648 ų |
| shell_volume | 2758 ų |
| envelope_diameter | 21.6 Å |
| shell_rg | 10.20 Å |
| envelope_rg | 6.61 Å |
| shape_rg | 6.19 Å |
| total_rg | 8.90 Å |
| total_atoms | 196 |
| n_residues | 2 |
| n_harmonics | 20 |
| q_range | — – 0.5000 Å−1 |
| n_points | 101 |
| shell_type | directional |
| solvent_density | 0.3340 e/ų |
| contrast_shell | 0.0300 e/ų |
| crysol_version | 4.1.3 |
3. P(r) Analysis (GNOM)
| dmax | 26.3 Å |
| rg_real | 7.71 Å |
| rg_real_error | 0.27 Å |
| i0_real | 2.9030e+04 |
| i0_real_error | 2.6950e+02 |
| rg_reciprocal | 7.71 Å |
| i0_reciprocal | 29030.0000 |
| total_estimate | 0.6442 |
| solution_quality | REASONABLE a REASONABLE solution |
| n_peaks | 2 |
| r_peak_primary | 9.7 Å |
| skewness | 0.323 |
| kurtosis | -0.191 |
| angular_range | — – 0.5000 Å−1 |
| current_alpha | 0.0000 |
| highest_alpha | 2966.0000 |
| n_real_points | 80 |
| gnom_version | 4.1.3 |
| quality_criteria | AN1: 0.000; Oscil: 0.813; Stabil: 0.996; Sysdev: 0.256; Positv: 1.000; Valcen: 0.904; Smooth: 0.269 |