1cyb
NMR STUDIES OF (U-13C)CYCLOSPORIN A BOUND TO CYCLOPHILIN: BOUND CONFORMATION AND PORTIONS OF CYCLOSPORIN INVOLVED IN BINDING
SAXS Profile
P(r) Distribution
1. Structure Basics
| entry_id | 1cyb |
| deposition_date | 1992-02-24 |
| title | NMR STUDIES OF (U-13C)CYCLOSPORIN A BOUND TO CYCLOPHILIN: BOUND CONFORMATION AND PORTIONS OF CYCLOSPORIN INVOLVED IN BINDING |
| keywords | IMMUNOSUPPRESSANT, CYCLOSPORIN A; IMMUNOSUPPRESSANT |
| method | SOLUTION NMR |
Download Data
2. SAXS Parameters (CRYSOL)
| rg_guinier | 3.12 Å |
| rg_electron | 6.02 Å |
| i0 | 2321490.00 |
| molecular_weight | 24234.0 kDa |
| excluded_volume | 35582 ų |
| envelope_volume | 2113 ų |
| shell_volume | 3236 ų |
| envelope_diameter | 22.3 Å |
| shell_rg | 10.75 Å |
| envelope_rg | 6.88 Å |
| shape_rg | 5.97 Å |
| total_rg | 6.83 Å |
| total_atoms | 3920 |
| n_residues | 40 |
| n_harmonics | 20 |
| q_range | — – 0.5000 Å−1 |
| n_points | 101 |
| shell_type | directional |
| solvent_density | 0.3340 e/ų |
| contrast_shell | 0.0300 e/ų |
| crysol_version | 4.1.3 |
3. P(r) Analysis (GNOM)
| dmax | 7.8 Å |
| rg_real | 3.33 Å |
| rg_real_error | 0.01 Å |
| i0_real | 2.4050e+06 |
| i0_real_error | 1.2200e+04 |
| rg_reciprocal | 1.74 Å |
| i0_reciprocal | 2321000.0000 |
| total_estimate | 0.6500 |
| solution_quality | REASONABLE a REASONABLE solution |
| n_peaks | 1 |
| r_peak_primary | 4.9 Å |
| skewness | -0.241 |
| kurtosis | -0.689 |
| angular_range | — – 0.5000 Å−1 |
| current_alpha | 0.2749 |
| highest_alpha | 33.2900 |
| n_real_points | 80 |
| gnom_version | 4.1.3 |
| quality_criteria | AN1: 0.001; Oscil: 1.000; Stabil: 0.943; Sysdev: 0.000; Positv: 1.000; Valcen: 0.777; Smooth: 0.000 |