CRYSTAL STRUCTURE OF FAB HGR-2 F6, A COMPETITIVE ANTAGONIST OF THE GLUCAGON RECEPTOR

entry_id	1dqd
deposition_date	2000-01-04
title	CRYSTAL STRUCTURE OF FAB HGR-2 F6, A COMPETITIVE ANTAGONIST OF THE GLUCAGON RECEPTOR
keywords	;Glucagon receptor, monoclonal antibody, Fab, receptor antagonist, typical immunoglobulin fold, light chain, heavy chain, antigen binding site, complementarity-determining regions, IMMUNE SYSTEM ;; IMMUNE SYSTEM
method	X-RAY DIFFRACTION

rg_guinier	25.59 Å
rg_electron	24.56 Å
i0	38545700.00
molecular_weight	47032.0 kDa
excluded_volume	58372 ų
envelope_volume	73094 ų
shell_volume	24847 ų
envelope_diameter	80.6 Å
shell_rg	31.77 Å
envelope_rg	24.27 Å
shape_rg	24.55 Å
total_rg	25.41 Å
total_atoms	3306
n_residues	435
n_harmonics	20
q_range	— – 0.5000 Å−1
n_points	101
shell_type	directional
solvent_density	0.3340 e/ų
contrast_shell	0.0300 e/ų
crysol_version	4.1.3

dmax	78.6 Å
rg_real	25.56 Å
rg_real_error	0.51 Å
i0_real	3.8550e+07
i0_real_error	6.1160e+05
rg_reciprocal	25.57 Å
i0_reciprocal	38550000.0000
total_estimate	0.9139
solution_quality	EXCELLENT a EXCELLENT solution
n_peaks	2
r_peak_primary	29.2 Å
skewness	0.249
kurtosis	-0.563
angular_range	— – 0.3100 Å−1
current_alpha	0.0000
highest_alpha	6296000.0000
n_real_points	63
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.975; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.995; Smooth: 0.955

Unit Cell

length_a	76.140 Å
length_b	133.740 Å
length_c	37.460 Å
angle_alpha	90.00 °
angle_beta	90.00 °
angle_gamma	90.00 °
z_pdb	4

Symmetry

space_group	P 21 21 2
int_tables_number	18
crystal_system	—

Refinement

resolution	2.100 Å
resolution_low	20.000 Å
r_factor	—
r_work	0.2170
r_free	0.3150

Diffraction

temperature

100.0 K

Files (7)

• pr_distribution /app/data/pr_computation/dq/1dqd/pr_distribution.json
• pr_output /app/data/pr_computation/dq/1dqd/1dqd.pr.out
• pr_plot /app/data/visualization/pr_computation/dq/1dqd/1dqd_pr_distribution.png
• saxs_curve_dat /app/data/saxs_computation/dq/1dqd/1dqd.dat
• saxs_fit /app/data/saxs_computation/dq/1dqd/1dqd.fit
• saxs_log /app/data/saxs_computation/dq/1dqd/1dqd.log
• saxs_plot /app/data/visualization/saxs_computation/dq/1dqd/1dqd_saxs_profile.png

Curves (3)

fit	/app/data/saxs_computation/dq/1dqd/1dqd.fit
pddf	/app/data/pr_computation/dq/1dqd/1dqd.pr.out
profile	/app/data/saxs_computation/dq/1dqd/1dqd.dat