1f6t

STRUCTURE OF THE NUCLEOSIDE DIPHOSPHATE KINASE/ALPHA-BORANO(RP)-TDP.MG COMPLEX

Method: X-RAY DIFFRACTION Dmax: 78.5 Å Quality: EXCELLENT

SAXS 散射曲线 SAXS Profile

SAXS profile for 1f6t

P(r) 距离分布 P(r) Distribution

P(r) distribution for 1f6t
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1. 结构基本信息 1. Structure Basics

条目编号 entry_id1f6t
沉积日期 deposition_date2000-06-23
结构标题 titleSTRUCTURE OF THE NUCLEOSIDE DIPHOSPHATE KINASE/ALPHA-BORANO(RP)-TDP.MG COMPLEX
关键词 keywordsNUCLEOSIDE DIPHOSPHATE KINASE, ANTI-HIV NUCLEOSIDE ANALOGUE, PHOSPHORYLATION, BORANOPHOSPHATE, TRANSFERASE; TRANSFERASE
实验方法 methodX-RAY DIFFRACTION

2. SAXS 参数 (CRYSOL 理论计算) 2. SAXS Parameters (CRYSOL)

回转半径 Rg (Guinier) rg_guinier25.11
回转半径 Rg (电子) rg_electron24.44
零角强度 I(0) i040065200.00
分子量 molecular_weight50032.0 kDa
排除体积 excluded_volume63099 ų
包络体积 envelope_volume73653 ų
水化壳体积 shell_volume25105 ų
包络直径 envelope_diameter78.2
壳层 Rg shell_rg31.49
包络 Rg envelope_rg24.58
形状 Rg shape_rg24.45
总 Rg total_rg25.19
总原子数 total_atoms3524
残基数 n_residues451
球谐函数阶数 n_harmonics20
q 范围 q_range— – 0.5000 −1
数据点数 n_points101
壳层类型 shell_typedirectional
溶剂电子密度 solvent_density0.3340 e/ų
壳层衬度 contrast_shell0.0300 e/ų
CRYSOL 版本 crysol_version4.1.3

3. P(r) 距离分布 (GNOM 反演) 3. P(r) Analysis (GNOM)

最大尺寸 Dmax dmax78.5
Rg (实空间) rg_real25.05
Rg 误差 (实空间) rg_real_error0.51
I(0) (实空间) i0_real4.0070e+07
I(0) 误差 (实空间) i0_real_error5.4700e+05
Rg (倒空间) rg_reciprocal25.07
I(0) (倒空间) i0_reciprocal40070000.0000
解质量估计 total_estimate0.9090
解质量评级 solution_quality EXCELLENT a EXCELLENT solution
P(r) 峰数 n_peaks2
主峰位置 r_peak_primary24.9
偏度 Skewness skewness0.185
峰度 Kurtosis kurtosis-0.692
角度范围 angular_range— – 0.3150 −1
当前正则化参数 α current_alpha0.0000
最高正则化参数 α highest_alpha17990000.0000
实空间数据点数 n_real_points64
GNOM 版本 gnom_version4.1.3
质量判据 quality_criteria AN1: 0.000; Oscil: 0.949; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.977; Smooth: 0.988

4. 晶体学与实验 4. Crystallography & Experiment

5. 实体与聚合体信息 (4)

6. 折叠分类 (SCOP + CATH) 6 domains

SCOP 2.08 (3 domains)

结构域编号 domain_idd1f6ta_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.58 — Ferredoxin-like
超家族 Superfamily superfamilyd.58.6 — Nucleoside diphosphate kinase, NDK
家族 Family familyd.58.6.1 — Nucleoside diphosphate kinase, NDK
结构域编号 domain_idd1f6tb_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.58 — Ferredoxin-like
超家族 Superfamily superfamilyd.58.6 — Nucleoside diphosphate kinase, NDK
家族 Family familyd.58.6.1 — Nucleoside diphosphate kinase, NDK
结构域编号 domain_idd1f6tc_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.58 — Ferredoxin-like
超家族 Superfamily superfamilyd.58.6 — Nucleoside diphosphate kinase, NDK
家族 Family familyd.58.6.1 — Nucleoside diphosphate kinase, NDK

CATH v4.4 (3 domains)

结构域编号 domain_id1f6tA00
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology70 — Alpha-Beta Plaits
同源超家族 H-superfamily homologous superfamily141 — Nucleoside diphosphate kinase-like domain
结构域编号 domain_id1f6tB00
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology70 — Alpha-Beta Plaits
同源超家族 H-superfamily homologous superfamily141 — Nucleoside diphosphate kinase-like domain
结构域编号 domain_id1f6tC00
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology70 — Alpha-Beta Plaits
同源超家族 H-superfamily homologous superfamily141 — Nucleoside diphosphate kinase-like domain

7. 引用文献 (1)

8. 文件与曲线 (10)