SAXSdb — 1g5u

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1. Protein Identity and Related Structures Protein Identity & Related Structures

PROFILIN

Hevea brasiliensis

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein monomer	Monomer	Protein 1	SODIUM ION × 1	Consistent with protein count
2	Protein monomer	Monomer	Protein 1	No other associated polymer	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	PROF6_HEVBR
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain A； PDBConstruct 1–131； UniProt 1–131 Author chain B； PDBConstruct 1–131； UniProt 1–131

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	1g5u
Deposition date deposition_date	2000-11-02
Structure title title	LATEX PROFILIN HEVB8
Keywords keywords	Allergen, ACTIN-BINDING PROTEIN; ALLERGEN
Experimental Method method	X-RAY DIFFRACTION

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

1g5u__assembly_2__model_1

Assembly 2 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

1g5u__assembly_2__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

1g5u__assembly_2__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	14.88 Å
Rg (electron density)	13.37 Å
Total Rg	14.56 Å
Atom count	976
Residues	130
Excluded volume	17308 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`1g5u__assembly_1__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
2	1	`1g5u__assembly_2__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (2)

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6. Fold Classification (SCOP + CATH) 4 domains

SCOP 2.08 (2 domains)

Domain ID domain_id	d1g5ua_
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.110 — Profilin-like
Superfamily Superfamily superfamily	d.110.1 — Profilin (actin-binding protein)
Family Family family	d.110.1.1 — Profilin (actin-binding protein)

Domain ID domain_id	d1g5ub_
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.110 — Profilin-like
Superfamily Superfamily superfamily	d.110.1 — Profilin (actin-binding protein)
Family Family family	d.110.1.1 — Profilin (actin-binding protein)

CATH v4.4 (2 domains)

Domain ID domain_id	1g5uA00
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	450 — Beta-Lactamase
Homologous superfamily homologous superfamily	30 — Dynein light chain 2a, cytoplasmic

Domain ID domain_id	1g5uB00
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	450 — Beta-Lactamase
Homologous superfamily homologous superfamily	30 — Dynein light chain 2a, cytoplasmic

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7. Citations (7)

A Comparative Structural Analysis of Allergen Profilins HEVB8 and BETV2

To be Published

PRIMARY

Latex Allergy in Children

INT.ARCH.ALLERGY.IMMUNOL (2000)

DOI: 10.1159/000024304

PROFILIN BINDS PROLINE-RICH LIGANDS IN TWO DISTINCT AMIDE BACKBONE ORIENTATIONS

Nat.Struct.Biol. (1999)

DOI: 10.1038/10722

CRYSTAL PACKING INDUCES A COnFORMATIONAL CHANGE IN PROFILIN-I FROM ACANTHAMOEBA CASTELLANII

J.STRUCT.BIOL. (1998)

DOI: 10.1006/jsbi.1998.4009

The Molecular Basis for Allergen Cross-reactivity: Crystal Structure and IgE-epitope Mapping of Birch Pollen Profilin

Structure (1997)

DOI: 10.1016/S0969-2126(97)00164-0

;X-ray Structures of Isoforms of the Actin-binding Protein Profilin that Differ in their Affinity for Phosphatidylinositol Phosphates ;

Proc.Natl.Acad.Sci.USA (1994)

PURIFICATION, CHARACTERIZATION AND CRYSTALLIZATION OF HUMAN PLATELET PROFILIN EXPRESSED IN ESCHERICHIA COLI

J.Mol.Biol. (1994)

DOI: 10.1006/jmbi.1994.1522

Unit-cell length a length_a	58.877 Å
Unit-cell length b length_b	58.877 Å
Unit-cell length c length_c	83.469 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	90.00 °
Unit-cell angle γ angle_gamma	120.00 °
Molecules per unit cell Z z_pdb	6

Space group space_group	P 32
Space-group number int_tables_number	145
Crystal system crystal_system	—

Resolution resolution	3.100 Å
Low-resolution limit resolution_low	19.300 Å
R factor r_factor	—
R_work r_work	0.2590
R_free r_free	0.3130

Description description	PROFILIN
Molecular weight formula_weight	14048.9 kDa
Source method src_method	man
Copy count entity_count	2

Polymer type type	polypeptide(L)
Chain IDs strand_id	A,B
Atom count atom_count	1953

LATEX PROFILIN HEVB8

1. Protein Identity and Related Structures Protein Identity & Related Structures

PROFILIN

State in the Current Structure

Other States of the Same Protein in the Database

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

1g5u__assembly_2__model_1

1g5u__assembly_2__model_1 | I(q)

1g5u__assembly_2__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (2)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 non-polymer

6. Fold Classification (SCOP + CATH) 4 domains

SCOP 2.08 (2 domains)

CATH v4.4 (2 domains)

7. Citations (7)

Source organism organism	Hevea brasiliensis
NCBI taxonomy ID ncbi_taxonomy_id	3981
Host organism host_organism	Escherichia coli

Description description	SODIUM ION
Molecular weight formula_weight	23.0 kDa
Source method src_method	syn
Copy count entity_count	1

LATEX PROFILIN HEVB8

1. Protein Identity and Related Structures Protein Identity & Related Structures

PROFILIN

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

1g5u__assembly_2__model_1

1g5u__assembly_2__model_1 | I(q)

1g5u__assembly_2__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (2)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 non-polymer

6. Fold Classification (SCOP + CATH) 4 domains

SCOP 2.08 (2 domains)

CATH v4.4 (2 domains)

7. Citations (7)