← Back to search
1g8k

CRYSTAL STRUCTURE ANALYSIS OF ARSENITE OXIDASE FROM ALCALIGENES FAECALIS

Method: X-RAY DIFFRACTION
▼

1. Protein Identity and Related Structures Protein Identity & Related Structures

ARSENITE OXIDASE

OrganismNot specified

UniProt Q7SIF4

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 2 ARSENITE OXIDASE × 1 （Q7SIF3） MERCURY (II) ION × 3 CALCIUM ION × 2 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE × 2 OXYGEN ATOM × 1 MOLYBDENUM(IV) ION × 1 FE3-S4 CLUSTER × 1 1,2-ETHANEDIOL × 2 FE2/S2 (INORGANIC) CLUSTER × 1 water × 2 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 2 ARSENITE OXIDASE × 1 （Q7SIF3） MERCURY (II) ION × 3 CALCIUM ION × 2 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE × 2 OXYGEN ATOM × 1 MOLYBDENUM(IV) ION × 1 FE3-S4 CLUSTER × 1 1,2-ETHANEDIOL × 2 FE2/S2 (INORGANIC) CLUSTER × 1 water × 2 Consistent with protein count
3 Protein heterocomplex Heteromer Protein 2 ARSENITE OXIDASE × 1 （Q7SIF3） MERCURY (II) ION × 3 CALCIUM ION × 2 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE × 2 OXYGEN ATOM × 1 MOLYBDENUM(IV) ION × 1 FE3-S4 CLUSTER × 1 1,2-ETHANEDIOL × 3 FE2/S2 (INORGANIC) CLUSTER × 1 water × 2 Consistent with protein count
4 Protein heterocomplex Heteromer Protein 2 ARSENITE OXIDASE × 1 （Q7SIF3） MERCURY (II) ION × 3 CALCIUM ION × 2 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE × 2 OXYGEN ATOM × 1 MOLYBDENUM(IV) ION × 1 FE3-S4 CLUSTER × 1 1,2-ETHANEDIOL × 2 FE2/S2 (INORGANIC) CLUSTER × 1 water × 2 Consistent with protein count
5 Protein heterocomplex Heteromer Protein 4 ARSENITE OXIDASE × 2 （Q7SIF3） MERCURY (II) ION × 6 CALCIUM ION × 4 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE × 4 OXYGEN ATOM × 2 MOLYBDENUM(IV) ION × 2 FE3-S4 CLUSTER × 2 1,2-ETHANEDIOL × 5 FE2/S2 (INORGANIC) CLUSTER × 2 water × 4 Consistent with protein count
6 Protein heterocomplex Heteromer Protein 4 ARSENITE OXIDASE × 2 （Q7SIF3） MERCURY (II) ION × 6 CALCIUM ION × 4 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE × 4 OXYGEN ATOM × 2 MOLYBDENUM(IV) ION × 2 FE3-S4 CLUSTER × 2 1,2-ETHANEDIOL × 4 FE2/S2 (INORGANIC) CLUSTER × 2 water × 4 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1g8j 1g8j 1g8k 1g8k 1g8k 1g8k 1g8k 1g8k 8cff 8cff 8cff 8cff

18 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name AOXB_ALCFA
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–825； UniProt 1–825 Author chain C； PDBConstruct 1–825； UniProt 1–825 Author chain E； PDBConstruct 1–825； UniProt 1–825 Author chain G； PDBConstruct 1–825； UniProt 1–825

ARSENITE OXIDASE

OrganismNot specified

UniProt Q7SIF3

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 2 ARSENITE OXIDASE × 1 （Q7SIF4） MERCURY (II) ION × 3 CALCIUM ION × 2 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE × 2 OXYGEN ATOM × 1 MOLYBDENUM(IV) ION × 1 FE3-S4 CLUSTER × 1 1,2-ETHANEDIOL × 2 FE2/S2 (INORGANIC) CLUSTER × 1 water × 2 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 2 ARSENITE OXIDASE × 1 （Q7SIF4） MERCURY (II) ION × 3 CALCIUM ION × 2 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE × 2 OXYGEN ATOM × 1 MOLYBDENUM(IV) ION × 1 FE3-S4 CLUSTER × 1 1,2-ETHANEDIOL × 2 FE2/S2 (INORGANIC) CLUSTER × 1 water × 2 Consistent with protein count
3 Protein heterocomplex Heteromer Protein 2 ARSENITE OXIDASE × 1 （Q7SIF4） MERCURY (II) ION × 3 CALCIUM ION × 2 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE × 2 OXYGEN ATOM × 1 MOLYBDENUM(IV) ION × 1 FE3-S4 CLUSTER × 1 1,2-ETHANEDIOL × 3 FE2/S2 (INORGANIC) CLUSTER × 1 water × 2 Consistent with protein count
4 Protein heterocomplex Heteromer Protein 2 ARSENITE OXIDASE × 1 （Q7SIF4） MERCURY (II) ION × 3 CALCIUM ION × 2 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE × 2 OXYGEN ATOM × 1 MOLYBDENUM(IV) ION × 1 FE3-S4 CLUSTER × 1 1,2-ETHANEDIOL × 2 FE2/S2 (INORGANIC) CLUSTER × 1 water × 2 Consistent with protein count
5 Protein heterocomplex Heteromer Protein 4 ARSENITE OXIDASE × 2 （Q7SIF4） MERCURY (II) ION × 6 CALCIUM ION × 4 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE × 4 OXYGEN ATOM × 2 MOLYBDENUM(IV) ION × 2 FE3-S4 CLUSTER × 2 1,2-ETHANEDIOL × 5 FE2/S2 (INORGANIC) CLUSTER × 2 water × 4 Consistent with protein count
6 Protein heterocomplex Heteromer Protein 4 ARSENITE OXIDASE × 2 （Q7SIF4） MERCURY (II) ION × 6 CALCIUM ION × 4 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE × 4 OXYGEN ATOM × 2 MOLYBDENUM(IV) ION × 2 FE3-S4 CLUSTER × 2 1,2-ETHANEDIOL × 4 FE2/S2 (INORGANIC) CLUSTER × 2 water × 4 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1g8j 1g8j 1g8k 1g8k 1g8k 1g8k 1g8k 1g8k 8cff 8cff 8cff 8cff

16 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name ARSS_ALCFA
Isoform —
PDB entities 2
Chains and sequence ranges Author chain B； PDBConstruct 1–133； UniProt 1–133 Author chain D； PDBConstruct 1–133； UniProt 1–133 Author chain F； PDBConstruct 1–133； UniProt 1–133 Author chain H； PDBConstruct 1–133； UniProt 1–133

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

▼

2. Structure Basics 2. Structure Basics

Entry ID entry_id1g8k
Deposition date deposition_date2000-11-17
Structure title titleCRYSTAL STRUCTURE ANALYSIS OF ARSENITE OXIDASE FROM ALCALIGENES FAECALIS
Keywords keywordsOXIDASE, ARSENITE, MOLYBDOPTERIN, [3Fe-4S] CLUSTER, [2Fe-2S] CLUSTER, RIESKE, OXIDOREDUCTASE; OXIDOREDUCTASE
Experimental Method methodX-RAY DIFFRACTION
▼

3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

1g8k__assembly_4__model_1

Assembly 4 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

1g8k__assembly_4__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

1g8k__assembly_4__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）28.56 Å
Rg (electron density)28.03 Å
Total Rg28.56 Å
Atom count7540
Residues955
Excluded volume132830 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 1g8k__assembly_1__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 1g8k__assembly_2__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
3 1 1g8k__assembly_3__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
4 1 1g8k__assembly_4__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
5 1 1g8k__assembly_5__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
6 1 1g8k__assembly_6__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
▶

4. Crystallography and Experiment 4. Crystallography & Experiment

▶

5. Entities and Polymers Entities & Polymers (11)

▼

6. Fold Classification (SCOP + CATH) 32 domains

SCOP 2.08 (12 domains)

Domain ID domain_idd1g8ka1
Class classb — All beta proteins
Fold Fold foldb.52 — Double psi beta-barrel
Superfamily Superfamily superfamilyb.52.2 — ADC-like
Family Family familyb.52.2.2 — Formate dehydrogenase/DMSO reductase, C-terminal domain
Domain ID domain_idd1g8ka2
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.81 — Formate dehydrogenase/DMSO reductase, domains 1-3
Superfamily Superfamily superfamilyc.81.1 — Formate dehydrogenase/DMSO reductase, domains 1-3
Family Family familyc.81.1.1 — Formate dehydrogenase/DMSO reductase, domains 1-3
Domain ID domain_idd1g8kb_
Class classb — All beta proteins
Fold Fold foldb.33 — ISP domain
Superfamily Superfamily superfamilyb.33.1 — ISP domain
Family Family familyb.33.1.1 — Rieske iron-sulfur protein (ISP)
Domain ID domain_idd1g8kc1
Class classb — All beta proteins
Fold Fold foldb.52 — Double psi beta-barrel
Superfamily Superfamily superfamilyb.52.2 — ADC-like
Family Family familyb.52.2.2 — Formate dehydrogenase/DMSO reductase, C-terminal domain
Domain ID domain_idd1g8kc2
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.81 — Formate dehydrogenase/DMSO reductase, domains 1-3
Superfamily Superfamily superfamilyc.81.1 — Formate dehydrogenase/DMSO reductase, domains 1-3
Family Family familyc.81.1.1 — Formate dehydrogenase/DMSO reductase, domains 1-3
Domain ID domain_idd1g8kd_
Class classb — All beta proteins
Fold Fold foldb.33 — ISP domain
Superfamily Superfamily superfamilyb.33.1 — ISP domain
Family Family familyb.33.1.1 — Rieske iron-sulfur protein (ISP)
Domain ID domain_idd1g8ke1
Class classb — All beta proteins
Fold Fold foldb.52 — Double psi beta-barrel
Superfamily Superfamily superfamilyb.52.2 — ADC-like
Family Family familyb.52.2.2 — Formate dehydrogenase/DMSO reductase, C-terminal domain
Domain ID domain_idd1g8ke2
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.81 — Formate dehydrogenase/DMSO reductase, domains 1-3
Superfamily Superfamily superfamilyc.81.1 — Formate dehydrogenase/DMSO reductase, domains 1-3
Family Family familyc.81.1.1 — Formate dehydrogenase/DMSO reductase, domains 1-3
Domain ID domain_idd1g8kf_
Class classb — All beta proteins
Fold Fold foldb.33 — ISP domain
Superfamily Superfamily superfamilyb.33.1 — ISP domain
Family Family familyb.33.1.1 — Rieske iron-sulfur protein (ISP)
Domain ID domain_idd1g8kg1
Class classb — All beta proteins
Fold Fold foldb.52 — Double psi beta-barrel
Superfamily Superfamily superfamilyb.52.2 — ADC-like
Family Family familyb.52.2.2 — Formate dehydrogenase/DMSO reductase, C-terminal domain
Domain ID domain_idd1g8kg2
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.81 — Formate dehydrogenase/DMSO reductase, domains 1-3
Superfamily Superfamily superfamilyc.81.1 — Formate dehydrogenase/DMSO reductase, domains 1-3
Family Family familyc.81.1.1 — Formate dehydrogenase/DMSO reductase, domains 1-3
Domain ID domain_idd1g8kh_
Class classb — All beta proteins
Fold Fold foldb.33 — ISP domain
Superfamily Superfamily superfamilyb.33.1 — ISP domain
Family Family familyb.33.1.1 — Rieske iron-sulfur protein (ISP)

CATH v4.4 (20 domains)

Domain ID domain_id1g8kA01
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology200 — Phosphorylase Kinase; domain 1
Homologous superfamily homologous superfamily200 —
Domain ID domain_id1g8kA02
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily740 —
Domain ID domain_id1g8kA03
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology228 — Dimethylsulfoxide Reductase; domain 2
Homologous superfamily homologous superfamily10 — Dimethylsulfoxide Reductase, domain 2
Domain ID domain_id1g8kA04
Class class2 — Mainly Beta
Architecture architecture40 — Beta Barrel
Topology topology40 — Barwin-like endoglucanases
Homologous superfamily homologous superfamily20 —
Domain ID domain_id1g8kB00
Class class2 — Mainly Beta
Architecture architecture102 — 3-layer Sandwich
Topology topology10 — Rieske Iron-sulfur Protein
Homologous superfamily homologous superfamily10 — Rieske [2Fe-2S] iron-sulphur domain
Domain ID domain_id1g8kC01
Class class2 — Mainly Beta
Architecture architecture60 — Sandwich
Topology topology40 — Immunoglobulin-like
Homologous superfamily homologous superfamily4210 —
Domain ID domain_id1g8kC02
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily740 —
Domain ID domain_id1g8kC03
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology228 — Dimethylsulfoxide Reductase; domain 2
Homologous superfamily homologous superfamily10 — Dimethylsulfoxide Reductase, domain 2
Domain ID domain_id1g8kC04
Class class2 — Mainly Beta
Architecture architecture40 — Beta Barrel
Topology topology40 — Barwin-like endoglucanases
Homologous superfamily homologous superfamily20 —
Domain ID domain_id1g8kD00
Class class2 — Mainly Beta
Architecture architecture102 — 3-layer Sandwich
Topology topology10 — Rieske Iron-sulfur Protein
Homologous superfamily homologous superfamily10 — Rieske [2Fe-2S] iron-sulphur domain
Domain ID domain_id1g8kE01
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology200 — Phosphorylase Kinase; domain 1
Homologous superfamily homologous superfamily200 —
Domain ID domain_id1g8kE02
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily740 —
Domain ID domain_id1g8kE03
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology228 — Dimethylsulfoxide Reductase; domain 2
Homologous superfamily homologous superfamily10 — Dimethylsulfoxide Reductase, domain 2
Domain ID domain_id1g8kE04
Class class2 — Mainly Beta
Architecture architecture40 — Beta Barrel
Topology topology40 — Barwin-like endoglucanases
Homologous superfamily homologous superfamily20 —
Domain ID domain_id1g8kF00
Class class2 — Mainly Beta
Architecture architecture102 — 3-layer Sandwich
Topology topology10 — Rieske Iron-sulfur Protein
Homologous superfamily homologous superfamily10 — Rieske [2Fe-2S] iron-sulphur domain
Domain ID domain_id1g8kG01
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology200 — Phosphorylase Kinase; domain 1
Homologous superfamily homologous superfamily200 —
Domain ID domain_id1g8kG02
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily740 —
Domain ID domain_id1g8kG03
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology228 — Dimethylsulfoxide Reductase; domain 2
Homologous superfamily homologous superfamily10 — Dimethylsulfoxide Reductase, domain 2
Domain ID domain_id1g8kG04
Class class2 — Mainly Beta
Architecture architecture40 — Beta Barrel
Topology topology40 — Barwin-like endoglucanases
Homologous superfamily homologous superfamily20 —
Domain ID domain_id1g8kH00
Class class2 — Mainly Beta
Architecture architecture102 — 3-layer Sandwich
Topology topology10 — Rieske Iron-sulfur Protein
Homologous superfamily homologous superfamily10 — Rieske [2Fe-2S] iron-sulphur domain
▶

7. Citations (2)