1gn2

S123C mutant of the iron-superoxide dismutase from Mycobacterium tuberculosis.

Method: X-RAY DIFFRACTION

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1. 蛋白身份与相关结构 Protein Identity & Related Structures

SUPEROXIDE DISMUTASE

MYCOBACTERIUM TUBERCULOSIS

当前结构中的状态

Assembly	物理组成	蛋白状态	分子拷贝数	共同组分	数据核对
1	蛋白同源多聚体	同源多聚体	蛋白 4	FE (III) ION × 4	与蛋白数一致
2	蛋白同源多聚体	同源多聚体	蛋白 4	FE (III) ION × 4	与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据

UniProt名称	SODF_MYCTU
Isoform	—
PDB实体	1
链与序列区间	作者链 A； PDB构建体 1–207； UniProt 1–207 作者链 B； PDB构建体 1–207； UniProt 1–207 作者链 C； PDB构建体 1–207； UniProt 1–207 作者链 D； PDB构建体 1–207； UniProt 1–207 作者链 E； PDB构建体 1–207； UniProt 1–207 作者链 F； PDB构建体 1–207； UniProt 1–207 作者链 G； PDB构建体 1–207； UniProt 1–207 作者链 H； PDB构建体 1–207； UniProt 1–207

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。

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2. 结构基本信息 2. Structure Basics

条目编号 entry_id	1gn2
沉积日期 deposition_date	2001-10-02
结构标题 title	S123C mutant of the iron-superoxide dismutase from Mycobacterium tuberculosis.
关键词 keywords	OXIDOREDUCTASE, IRON; OXIDOREDUCTASE
实验方法 method	X-RAY DIFFRACTION

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3. Official assembly/model 理论 SAXS Official SAXS Profiles

页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。

1gn2__assembly_2__model_1

Assembly 2 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

下载该曲线 .dat

1gn2__assembly_2__model_1 | I(q)

100 个绘图点；横轴和纵轴均采用对数尺度。

1gn2__assembly_2__model_1 | P(r) · Pending

P(r) 将按相同 assembly/model 分别计算和展示。

Rg（Guinier）	27.01 Å
Rg（电子密度）	25.69 Å
总 Rg	26.61 Å
原子数	6276
残基数	792
排除体积	110790 Å³
最大 q	0.500 Å⁻¹

Assembly	Model	结构单元	聚集说明	状态	CRYSOL	操作
1	1	`1gn2__assembly_1__model_1`	tetrameric （4）	成功	4.1.3-1-20251215 (887e7ef)	查看下载
2	1	`1gn2__assembly_2__model_1`	tetrameric （4）	成功	4.1.3-1-20251215 (887e7ef)	查看下载

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4. 晶体学与实验 4. Crystallography & Experiment

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5. 实体与聚合物信息 Entities & Polymers (2)

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6. 折叠分类 (SCOP + CATH) 32 domains

SCOP 2.08 (16 domains)

结构域编号 domain_id	d1gn2a1
类 Class class	a — All alpha proteins
折叠类型 Fold fold	a.2 — Long alpha-hairpin
超家族 Superfamily superfamily	a.2.11 — Fe,Mn superoxide dismutase (SOD), N-terminal domain
家族 Family family	a.2.11.1 — Fe,Mn superoxide dismutase (SOD), N-terminal domain

结构域编号 domain_id	d1gn2a2
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.44 — Fe,Mn superoxide dismutase (SOD), C-terminal domain
超家族 Superfamily superfamily	d.44.1 — Fe,Mn superoxide dismutase (SOD), C-terminal domain
家族 Family family	d.44.1.1 — Fe,Mn superoxide dismutase (SOD), C-terminal domain

结构域编号 domain_id	d1gn2b1
类 Class class	a — All alpha proteins
折叠类型 Fold fold	a.2 — Long alpha-hairpin
超家族 Superfamily superfamily	a.2.11 — Fe,Mn superoxide dismutase (SOD), N-terminal domain
家族 Family family	a.2.11.1 — Fe,Mn superoxide dismutase (SOD), N-terminal domain

结构域编号 domain_id	d1gn2b2
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.44 — Fe,Mn superoxide dismutase (SOD), C-terminal domain
超家族 Superfamily superfamily	d.44.1 — Fe,Mn superoxide dismutase (SOD), C-terminal domain
家族 Family family	d.44.1.1 — Fe,Mn superoxide dismutase (SOD), C-terminal domain

结构域编号 domain_id	d1gn2c1
类 Class class	a — All alpha proteins
折叠类型 Fold fold	a.2 — Long alpha-hairpin
超家族 Superfamily superfamily	a.2.11 — Fe,Mn superoxide dismutase (SOD), N-terminal domain
家族 Family family	a.2.11.1 — Fe,Mn superoxide dismutase (SOD), N-terminal domain

结构域编号 domain_id	d1gn2c2
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.44 — Fe,Mn superoxide dismutase (SOD), C-terminal domain
超家族 Superfamily superfamily	d.44.1 — Fe,Mn superoxide dismutase (SOD), C-terminal domain
家族 Family family	d.44.1.1 — Fe,Mn superoxide dismutase (SOD), C-terminal domain

结构域编号 domain_id	d1gn2d1
类 Class class	a — All alpha proteins
折叠类型 Fold fold	a.2 — Long alpha-hairpin
超家族 Superfamily superfamily	a.2.11 — Fe,Mn superoxide dismutase (SOD), N-terminal domain
家族 Family family	a.2.11.1 — Fe,Mn superoxide dismutase (SOD), N-terminal domain

结构域编号 domain_id	d1gn2d2
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.44 — Fe,Mn superoxide dismutase (SOD), C-terminal domain
超家族 Superfamily superfamily	d.44.1 — Fe,Mn superoxide dismutase (SOD), C-terminal domain
家族 Family family	d.44.1.1 — Fe,Mn superoxide dismutase (SOD), C-terminal domain

结构域编号 domain_id	d1gn2e1
类 Class class	a — All alpha proteins
折叠类型 Fold fold	a.2 — Long alpha-hairpin
超家族 Superfamily superfamily	a.2.11 — Fe,Mn superoxide dismutase (SOD), N-terminal domain
家族 Family family	a.2.11.1 — Fe,Mn superoxide dismutase (SOD), N-terminal domain

结构域编号 domain_id	d1gn2e2
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.44 — Fe,Mn superoxide dismutase (SOD), C-terminal domain
超家族 Superfamily superfamily	d.44.1 — Fe,Mn superoxide dismutase (SOD), C-terminal domain
家族 Family family	d.44.1.1 — Fe,Mn superoxide dismutase (SOD), C-terminal domain

结构域编号 domain_id	d1gn2f1
类 Class class	a — All alpha proteins
折叠类型 Fold fold	a.2 — Long alpha-hairpin
超家族 Superfamily superfamily	a.2.11 — Fe,Mn superoxide dismutase (SOD), N-terminal domain
家族 Family family	a.2.11.1 — Fe,Mn superoxide dismutase (SOD), N-terminal domain

结构域编号 domain_id	d1gn2f2
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.44 — Fe,Mn superoxide dismutase (SOD), C-terminal domain
超家族 Superfamily superfamily	d.44.1 — Fe,Mn superoxide dismutase (SOD), C-terminal domain
家族 Family family	d.44.1.1 — Fe,Mn superoxide dismutase (SOD), C-terminal domain

结构域编号 domain_id	d1gn2g1
类 Class class	a — All alpha proteins
折叠类型 Fold fold	a.2 — Long alpha-hairpin
超家族 Superfamily superfamily	a.2.11 — Fe,Mn superoxide dismutase (SOD), N-terminal domain
家族 Family family	a.2.11.1 — Fe,Mn superoxide dismutase (SOD), N-terminal domain

结构域编号 domain_id	d1gn2g2
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.44 — Fe,Mn superoxide dismutase (SOD), C-terminal domain
超家族 Superfamily superfamily	d.44.1 — Fe,Mn superoxide dismutase (SOD), C-terminal domain
家族 Family family	d.44.1.1 — Fe,Mn superoxide dismutase (SOD), C-terminal domain

结构域编号 domain_id	d1gn2h1
类 Class class	a — All alpha proteins
折叠类型 Fold fold	a.2 — Long alpha-hairpin
超家族 Superfamily superfamily	a.2.11 — Fe,Mn superoxide dismutase (SOD), N-terminal domain
家族 Family family	a.2.11.1 — Fe,Mn superoxide dismutase (SOD), N-terminal domain

结构域编号 domain_id	d1gn2h2
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.44 — Fe,Mn superoxide dismutase (SOD), C-terminal domain
超家族 Superfamily superfamily	d.44.1 — Fe,Mn superoxide dismutase (SOD), C-terminal domain
家族 Family family	d.44.1.1 — Fe,Mn superoxide dismutase (SOD), C-terminal domain

CATH v4.4 (16 domains)

结构域编号 domain_id	1gn2A01
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily	990 — Fe,Mn superoxide dismutase (SOD) domain

结构域编号 domain_id	1gn2A02
类 Class class	3 — Alpha Beta
架构 Architecture architecture	55 — 3-Layer(bab) Sandwich
拓扑 Topology topology	40 — minor pseudopilin epsh fold
同源超家族 H-superfamily homologous superfamily	20 — Iron/manganese superoxide dismutase, C-terminal domain

结构域编号 domain_id	1gn2B01
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily	990 — Fe,Mn superoxide dismutase (SOD) domain

结构域编号 domain_id	1gn2B02
类 Class class	3 — Alpha Beta
架构 Architecture architecture	55 — 3-Layer(bab) Sandwich
拓扑 Topology topology	40 — minor pseudopilin epsh fold
同源超家族 H-superfamily homologous superfamily	20 — Iron/manganese superoxide dismutase, C-terminal domain

结构域编号 domain_id	1gn2C01
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily	990 — Fe,Mn superoxide dismutase (SOD) domain

结构域编号 domain_id	1gn2C02
类 Class class	3 — Alpha Beta
架构 Architecture architecture	55 — 3-Layer(bab) Sandwich
拓扑 Topology topology	40 — minor pseudopilin epsh fold
同源超家族 H-superfamily homologous superfamily	20 — Iron/manganese superoxide dismutase, C-terminal domain

结构域编号 domain_id	1gn2D01
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily	990 — Fe,Mn superoxide dismutase (SOD) domain

结构域编号 domain_id	1gn2D02
类 Class class	3 — Alpha Beta
架构 Architecture architecture	55 — 3-Layer(bab) Sandwich
拓扑 Topology topology	40 — minor pseudopilin epsh fold
同源超家族 H-superfamily homologous superfamily	20 — Iron/manganese superoxide dismutase, C-terminal domain

结构域编号 domain_id	1gn2E01
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily	990 — Fe,Mn superoxide dismutase (SOD) domain

结构域编号 domain_id	1gn2E02
类 Class class	3 — Alpha Beta
架构 Architecture architecture	55 — 3-Layer(bab) Sandwich
拓扑 Topology topology	40 — minor pseudopilin epsh fold
同源超家族 H-superfamily homologous superfamily	20 — Iron/manganese superoxide dismutase, C-terminal domain

结构域编号 domain_id	1gn2F01
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily	990 — Fe,Mn superoxide dismutase (SOD) domain

结构域编号 domain_id	1gn2F02
类 Class class	3 — Alpha Beta
架构 Architecture architecture	55 — 3-Layer(bab) Sandwich
拓扑 Topology topology	40 — minor pseudopilin epsh fold
同源超家族 H-superfamily homologous superfamily	20 — Iron/manganese superoxide dismutase, C-terminal domain

结构域编号 domain_id	1gn2G01
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily	990 — Fe,Mn superoxide dismutase (SOD) domain

结构域编号 domain_id	1gn2G02
类 Class class	3 — Alpha Beta
架构 Architecture architecture	55 — 3-Layer(bab) Sandwich
拓扑 Topology topology	40 — minor pseudopilin epsh fold
同源超家族 H-superfamily homologous superfamily	20 — Iron/manganese superoxide dismutase, C-terminal domain

结构域编号 domain_id	1gn2H01
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily	990 — Fe,Mn superoxide dismutase (SOD) domain

结构域编号 domain_id	1gn2H02
类 Class class	3 — Alpha Beta
架构 Architecture architecture	55 — 3-Layer(bab) Sandwich
拓扑 Topology topology	40 — minor pseudopilin epsh fold
同源超家族 H-superfamily homologous superfamily	20 — Iron/manganese superoxide dismutase, C-terminal domain

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晶胞边长 a length_a	103.080 Å
晶胞边长 b length_b	106.330 Å
晶胞边长 c length_c	76.100 Å
晶胞夹角 α angle_alpha	90.00 °
晶胞夹角 β angle_beta	92.37 °
晶胞夹角 γ angle_gamma	90.00 °
晶胞分子数 Z z_pdb	16

空间群 space_group	P 1 21 1
空间群编号 int_tables_number	4
晶系 crystal_system	—

分辨率 resolution	3.400 Å
最低分辨率 resolution_low	21.000 Å
R 因子 r_factor	—
R_work r_work	0.2490
R_free r_free	0.2700

描述 description	SUPEROXIDE DISMUTASE
分子量 formula_weight	23076.9 kDa
EC 编号 ec_number	1.15.1.1
突变 mutation	YES
来源方法 src_method	man
拷贝数 entity_count	8

聚合物类型 type	polypeptide(L)
链编号 strand_id	A,B,C,D,E,F,G,H
原子数 atom_count	12552

S123C mutant of the iron-superoxide dismutase from Mycobacterium tuberculosis.

1. 蛋白身份与相关结构 Protein Identity & Related Structures

SUPEROXIDE DISMUTASE

当前结构中的状态

数据库中的同蛋白其他状态

2. 结构基本信息 2. Structure Basics

3. Official assembly/model 理论 SAXS Official SAXS Profiles

1gn2__assembly_2__model_1

1gn2__assembly_2__model_1 | I(q)

1gn2__assembly_2__model_1 | P(r) · Pending

4. 晶体学与实验 4. Crystallography & Experiment

晶胞参数 Unit Cell

对称性 Symmetry

精修参数 Refinement

衍射实验 Diffraction

5. 实体与聚合物信息 Entities & Polymers (2)

实体 1 Entity 1 polymer

聚合物 Polymer

来源 Source

实体 2 Entity 2 non-polymer

6. 折叠分类 (SCOP + CATH) 32 domains

SCOP 2.08 (16 domains)

CATH v4.4 (16 domains)

7. 引用文献 (2)

来源生物 organism	MYCOBACTERIUM TUBERCULOSIS
NCBI 分类编号 ncbi_taxonomy_id	1773
宿主生物 host_organism	MYCOBACTERIUM VACCAE

描述 description	FE (III) ION
分子量 formula_weight	55.8 kDa
来源方法 src_method	syn
拷贝数 entity_count	8

S123C mutant of the iron-superoxide dismutase from Mycobacterium tuberculosis.

1. 蛋白身份与相关结构 Protein Identity & Related Structures

SUPEROXIDE DISMUTASE

当前结构中的状态

数据库中的同蛋白其他状态

单体

同源二聚体

同源四聚体

其他同源多聚体

异源或核酸复合物

2. 结构基本信息 2. Structure Basics

3. Official assembly/model 理论 SAXS Official SAXS Profiles

1gn2__assembly_2__model_1

1gn2__assembly_2__model_1 | I(q)

1gn2__assembly_2__model_1 | P(r) · Pending

4. 晶体学与实验 4. Crystallography & Experiment

晶胞参数 Unit Cell

对称性 Symmetry

精修参数 Refinement

衍射实验 Diffraction

5. 实体与聚合物信息 Entities & Polymers (2)

实体 1 Entity 1 polymer

聚合物 Polymer

来源 Source

实体 2 Entity 2 non-polymer

6. 折叠分类 (SCOP + CATH) 32 domains

SCOP 2.08 (16 domains)

CATH v4.4 (16 domains)

7. 引用文献 (2)