1h3n
Leucyl-tRNA synthetase from Thermus thermophilus complexed with a sulphamoyl analogue of leucyl-adenylate
1. 蛋白身份与相关结构 Protein Identity & Related Structures
当前条目没有可用的 UniProt 蛋白身份。
七张关系表仍保留该条目的 assembly 与组成信息，但缺少统一蛋白身份时，不能可靠建立跨 PDB 的同蛋白链接。
当前条目的 assembly 组成
| Assembly | 物理组成 | 蛋白状态 | 蛋白 / DNA / RNA / 其他聚合物 | 数据核对 |
|---|---|---|---|---|
| 1 | 蛋白单体 | 单体 | 1 / 0 / 0 / 0 | 与蛋白数一致 |
页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。
2. 结构基本信息 2. Structure Basics
| 条目编号 entry_id | 1h3n |
| 沉积日期 deposition_date | 2002-09-11 |
| 结构标题 title | Leucyl-tRNA synthetase from Thermus thermophilus complexed with a sulphamoyl analogue of leucyl-adenylate |
| 关键词 keywords | ;AMINOACYL-TRNA SYNTHETASE, CLASS I AMINOACYL-TRNA SYNTHETASE, ATP + L-LEUCINE + TRNA (LEU) -> AMP + PPI + L-LEUCYL-TRNA(LEU), LIGASE ;; LIGASE |
| 实验方法 method | X-RAY DIFFRACTION |
3. Official assembly/model 理论 SAXS Official SAXS Profiles
页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。
1h3n__assembly_1__model_1
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
1h3n__assembly_1__model_1 | I(q)
1h3n__assembly_1__model_1 | P(r) · Pending
| Rg（Guinier） | 33.23 Å |
| Rg（电子密度） | 32.78 Å |
| 总 Rg | 33.25 Å |
| 原子数 | 6690 |
| 残基数 | 814 |
| 排除体积 | 119190 ų |
| 最大 q | 0.500 Å⁻¹ |
4. 晶体学与实验 4. Crystallography & Experiment
5. 实体与聚合物信息 Entities & Polymers (6)
6. 折叠分类 (SCOP + CATH) 7 domains
SCOP 2.08 (3 domains)
| 结构域编号 domain_id | d1h3na1 |
| 类 Class class | a — All alpha proteins |
| 折叠类型 Fold fold | a.27 — Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| 超家族 Superfamily superfamily | a.27.1 — Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| 家族 Family family | a.27.1.1 — Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| 结构域编号 domain_id | d1h3na2 |
| 类 Class class | b — All beta proteins |
| 折叠类型 Fold fold | b.51 — ValRS/IleRS/LeuRS editing domain |
| 超家族 Superfamily superfamily | b.51.1 — ValRS/IleRS/LeuRS editing domain |
| 家族 Family family | b.51.1.1 — ValRS/IleRS/LeuRS editing domain |
| 结构域编号 domain_id | d1h3na3 |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.26 — Adenine nucleotide alpha hydrolase-like |
| 超家族 Superfamily superfamily | c.26.1 — Nucleotidylyl transferase |
| 家族 Family family | c.26.1.1 — Class I aminoacyl-tRNA synthetases (RS), catalytic domain |
CATH v4.4 (4 domains)
| 结构域编号 domain_id | 1h3nA01 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 50 — Rossmann fold |
| 同源超家族 H-superfamily homologous superfamily | 620 — HUPs |
| 结构域编号 domain_id | 1h3nA02 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 90 — Alpha-Beta Complex |
| 拓扑 Topology topology | 740 — Isoleucyl-tRNA Synthetase; domain 2 |
| 同源超家族 H-superfamily homologous superfamily | 10 — Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain |
| 结构域编号 domain_id | 1h3nA03 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 30 — Roll |
| 拓扑 Topology topology | 210 — Leucyl-tRNA synthetase, domain 3 |
| 同源超家族 H-superfamily homologous superfamily | 10 — Leucyl-tRNA synthetase, domain 3 |
| 结构域编号 domain_id | 1h3nA04 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 730 — Isoleucyl-tRNA Synthetase; Domain 1 |
| 同源超家族 H-superfamily homologous superfamily | 10 — Isoleucyl-tRNA Synthetase; Domain 1 |