1h4v

HISTIDYL-TRNA SYNTHETASE from Thermus Thermophilus (ligand free)

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

HISTIDYL-TRNA SYNTHETASE

OrganismNot specified

UniProt P56194

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein homooligomer Homooligomer Protein 2 SULFATE ION × 2 water × 2 Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SYH_THETH
Isoform —
PDB entities 1
Chains and sequence ranges Author chain B; PDBConstruct 1–421; UniProt 1–421

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id1h4v
Deposition date deposition_date2001-05-14
Structure title titleHISTIDYL-TRNA SYNTHETASE from Thermus Thermophilus (ligand free)
Keywords keywordsTRNA SYNTHETASE, CLASS IIA AMINOACYL-TRNA SYNTHETASE, ATP + L-HISTIDINE TRNA(HIS)-> AMP + PPI + L-HISTIDYL-TRNA(HIS); TRNA SYNTHETASE
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

1h4v__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

1h4v__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

1h4v__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)31.64 Å
Rg (electron density)30.83 Å
Total Rg31.44 Å
Atom count6382
Residues808
Excluded volume113600 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 1h4v__assembly_1__model_1 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

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6. Fold Classification (SCOP + CATH) 4 domains

SCOP 2.08 (2 domains)

Domain ID domain_idd1h4vb1
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.51 — Anticodon-binding domain-like
Superfamily Superfamily superfamilyc.51.1 — Class II aaRS ABD-related
Family Family familyc.51.1.1 — Anticodon-binding domain of Class II aaRS
Domain ID domain_idd1h4vb2
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.104 — Class II aaRS and biotin synthetases
Superfamily Superfamily superfamilyd.104.1 — Class II aaRS and biotin synthetases
Family Family familyd.104.1.1 — Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain

CATH v4.4 (2 domains)

Domain ID domain_id1h4vB01
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology930 — BirA Bifunctional Protein; domain 2
Homologous superfamily homologous superfamily10 — Bira Bifunctional Protein; Domain 2
Domain ID domain_id1h4vB02
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily800 — Anticodon-binding domain
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7. Citations (2)