1jzs

Isoleucyl-tRNA synthetase Complexed with mupirocin

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Isoleucyl-tRNA synthetase

Thermus thermophilus

UniProt P56690

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein monomer Monomer Protein 1 ZINC ION × 2 MUPIROCIN × 1 Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SYI_THET8
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A; PDBConstruct 1–821; UniProt 1–821

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id1jzs
Deposition date deposition_date2001-09-17
Structure title titleIsoleucyl-tRNA synthetase Complexed with mupirocin
Keywords keywordsaminoacyl-tRNA synthetase, RIKEN Structural Genomics/Proteomics Initiative, RSGI, Structural Genomics, LIGASE; LIGASE
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

1jzs__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

1jzs__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

1jzs__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)34.58 Å
Rg (electron density)34.40 Å
Total Rg34.93 Å
Atom count6735
Residues821
Excluded volume120230 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 1jzs__assembly_1__model_1 monomeric (1) Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

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6. Fold Classification (SCOP + CATH) 6 domains

SCOP 2.08 (3 domains)

Domain ID domain_idd1jzsa1
Class classa — All alpha proteins
Fold Fold folda.27 — Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
Superfamily Superfamily superfamilya.27.1 — Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
Family Family familya.27.1.1 — Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
Domain ID domain_idd1jzsa2
Class classb — All beta proteins
Fold Fold foldb.51 — ValRS/IleRS/LeuRS editing domain
Superfamily Superfamily superfamilyb.51.1 — ValRS/IleRS/LeuRS editing domain
Family Family familyb.51.1.1 — ValRS/IleRS/LeuRS editing domain
Domain ID domain_idd1jzsa3
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.26 — Adenine nucleotide alpha hydrolase-like
Superfamily Superfamily superfamilyc.26.1 — Nucleotidylyl transferase
Family Family familyc.26.1.1 — Class I aminoacyl-tRNA synthetases (RS), catalytic domain

CATH v4.4 (3 domains)

Domain ID domain_id1jzsA01
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily620 — HUPs
Domain ID domain_id1jzsA02
Class class3 — Alpha Beta
Architecture architecture90 — Alpha-Beta Complex
Topology topology740 — Isoleucyl-tRNA Synthetase; domain 2
Homologous superfamily homologous superfamily10 — Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain
Domain ID domain_id1jzsA03
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology730 — Isoleucyl-tRNA Synthetase; Domain 1
Homologous superfamily homologous superfamily10 — Isoleucyl-tRNA Synthetase; Domain 1
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7. Citations (1)