← Back to search
1kuw

High-Resolution Structure and Localization of Amylin Nucleation Site in Detergent Micelles

Method: SOLUTION NMR
▼

1. Protein Identity and Related Structures Protein Identity & Related Structures

Islet amyloid polypeptide

OrganismNot specified

UniProt P10997

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein monomer Monomer Protein 1 No other associated polymer Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1kuw 2kb8 2l86 3fr1 5mgq 6ucj 6uck

7 assemblies

Homodimer
3fr1 3fr1

2 assemblies

Homotetramer

None

Other homooligomers
5knz 5ko0 6y1a 6zrf 6zrq 6zrr 7m61 7m62 7m64 7m65 7ykw 7yl0

39 assemblies; showing the first 12

Heteromeric or nucleic-acid complex
2g48 2g48 3g7v 3g7v 3g7w 3g7w 3hgz 3hgz 5k5g 6vw2 7bg0 7bg0

14 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name IAPP_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–10； UniProt 53–62

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

▼

2. Structure Basics 2. Structure Basics

Entry ID entry_id1kuw
Deposition date deposition_date2002-01-22
Structure title titleHigh-Resolution Structure and Localization of Amylin Nucleation Site in Detergent Micelles
Keywords keywordsamylin, hIAPP, micelles, orientation, HORMONE-GROWTH FACTOR COMPLEX; HORMONE/GROWTH FACTOR
Experimental Method methodSOLUTION NMR
▼

3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

1kuw__assembly_1__model_36

Assembly 1 · Model 36 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

1kuw__assembly_1__model_36 | I(q)

10-2 10-1 104 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

1kuw__assembly_1__model_36 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）7.17 Å
Rg (electron density)5.60 Å
Total Rg7.58 Å
Atom count139
Residues10
Excluded volume1234 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 1kuw__assembly_1__model_1 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 2 1kuw__assembly_1__model_2 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 3 1kuw__assembly_1__model_3 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 4 1kuw__assembly_1__model_4 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 5 1kuw__assembly_1__model_5 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 6 1kuw__assembly_1__model_6 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 7 1kuw__assembly_1__model_7 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 8 1kuw__assembly_1__model_8 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 9 1kuw__assembly_1__model_9 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 10 1kuw__assembly_1__model_10 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 11 1kuw__assembly_1__model_11 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 12 1kuw__assembly_1__model_12 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 13 1kuw__assembly_1__model_13 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 14 1kuw__assembly_1__model_14 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 15 1kuw__assembly_1__model_15 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 16 1kuw__assembly_1__model_16 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 17 1kuw__assembly_1__model_17 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 18 1kuw__assembly_1__model_18 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 19 1kuw__assembly_1__model_19 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 20 1kuw__assembly_1__model_20 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 21 1kuw__assembly_1__model_21 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 22 1kuw__assembly_1__model_22 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 23 1kuw__assembly_1__model_23 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 24 1kuw__assembly_1__model_24 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 25 1kuw__assembly_1__model_25 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 26 1kuw__assembly_1__model_26 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 27 1kuw__assembly_1__model_27 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 28 1kuw__assembly_1__model_28 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 29 1kuw__assembly_1__model_29 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 30 1kuw__assembly_1__model_30 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 31 1kuw__assembly_1__model_31 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 32 1kuw__assembly_1__model_32 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 33 1kuw__assembly_1__model_33 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 34 1kuw__assembly_1__model_34 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 35 1kuw__assembly_1__model_35 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 36 1kuw__assembly_1__model_36 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 37 1kuw__assembly_1__model_37 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 38 1kuw__assembly_1__model_38 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 39 1kuw__assembly_1__model_39 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
▶

4. Crystallography and Experiment 4. Crystallography & Experiment

▶

5. Entities and Polymers Entities & Polymers (1)

▼

6. Fold Classification (SCOP + CATH) 1 domains

SCOP 2.08 (1 domains)

Domain ID domain_idd1kuwa_
Class classj — Peptides
Fold Fold foldj.42 — Amyloid peptides
Superfamily Superfamily superfamilyj.42.1 — Amyloid peptides
Family Family familyj.42.1.1 — Amyloid peptides
▶

7. Citations (1)