1l5a

Crystal Structure of VibH, an NRPS Condensation Enzyme

Method: X-RAY DIFFRACTION
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1. 蛋白身份与相关结构 Protein Identity & Related Structures

amide synthase

Vibrio cholerae

UniProt Q9KTV9

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白同源多聚体 同源多聚体 蛋白 3 water × 3 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 Q9KTV9_VIBCH
Isoform —
PDB实体 1
链与序列区间 作者链 A; PDB构建体 1–436; UniProt 1–436 作者链 B; PDB构建体 1–436; UniProt 1–436 作者链 C; PDB构建体 1–436; UniProt 1–436

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中;数据库内部编号、导入时间和 assembly 操作表达式仅用于维护,因此不在读者页面展示。

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2. 结构基本信息 2. Structure Basics

条目编号 entry_id1l5a
沉积日期 deposition_date2002-03-06
结构标题 titleCrystal Structure of VibH, an NRPS Condensation Enzyme
关键词 keywordsnonribosomal peptide synthetase, NRPS condensation domain, amide synthase, vibriobactin, BIOSYNTHETIC PROTEIN; BIOSYNTHETIC PROTEIN
实验方法 methodX-RAY DIFFRACTION
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3. Official assembly/model 理论 SAXS Official SAXS Profiles

页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。

1l5a__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

下载该曲线 .dat

1l5a__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 个绘图点;横轴和纵轴均采用对数尺度。

1l5a__assembly_1__model_1 | P(r) · Pending

新版 assembly/model P(r) 尚未计算 此处仅保留位置,不展示旧数据 r (Angstrom) P(r)
P(r) 将按相同 assembly/model 分别计算和展示。
Rg(Guinier)37.49 Å
Rg(电子密度)36.52 Å
总 Rg37.05 Å
原子数10118
残基数1272
排除体积179050 ų
最大 q0.500 Å⁻¹
Assembly Model 结构单元 聚集说明 状态 CRYSOL 操作
1 1 1l5a__assembly_1__model_1 trimeric (3) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
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4. 晶体学与实验 4. Crystallography & Experiment

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5. 实体与聚合物信息 Entities & Polymers (2)

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6. 折叠分类 (SCOP + CATH) 15 domains

SCOP 2.08 (6 domains)

结构域编号 domain_idd1l5aa1
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.43 — CoA-dependent acyltransferases
超家族 Superfamily superfamilyc.43.1 — CoA-dependent acyltransferases
家族 Family familyc.43.1.2 — NRPS condensation domain (amide synthase)
结构域编号 domain_idd1l5aa2
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.43 — CoA-dependent acyltransferases
超家族 Superfamily superfamilyc.43.1 — CoA-dependent acyltransferases
家族 Family familyc.43.1.2 — NRPS condensation domain (amide synthase)
结构域编号 domain_idd1l5ab1
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.43 — CoA-dependent acyltransferases
超家族 Superfamily superfamilyc.43.1 — CoA-dependent acyltransferases
家族 Family familyc.43.1.2 — NRPS condensation domain (amide synthase)
结构域编号 domain_idd1l5ab2
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.43 — CoA-dependent acyltransferases
超家族 Superfamily superfamilyc.43.1 — CoA-dependent acyltransferases
家族 Family familyc.43.1.2 — NRPS condensation domain (amide synthase)
结构域编号 domain_idd1l5ac1
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.43 — CoA-dependent acyltransferases
超家族 Superfamily superfamilyc.43.1 — CoA-dependent acyltransferases
家族 Family familyc.43.1.2 — NRPS condensation domain (amide synthase)
结构域编号 domain_idd1l5ac2
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.43 — CoA-dependent acyltransferases
超家族 Superfamily superfamilyc.43.1 — CoA-dependent acyltransferases
家族 Family familyc.43.1.2 — NRPS condensation domain (amide synthase)

CATH v4.4 (9 domains)

结构域编号 domain_id1l5aA01
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology559 — Chloramphenicol Acetyltransferase
同源超家族 H-superfamily homologous superfamily10 — Chloramphenicol acetyltransferase-like domain
结构域编号 domain_id1l5aA02
类 Class class6 — Special
架构 Architecture architecture10 — Helix non-globular
拓扑 Topology topology250 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
同源超家族 H-superfamily homologous superfamily80 —
结构域编号 domain_id1l5aA03
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology559 — Chloramphenicol Acetyltransferase
同源超家族 H-superfamily homologous superfamily30 — Nonribosomal peptide synthetase, condensation domain
结构域编号 domain_id1l5aB01
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology559 — Chloramphenicol Acetyltransferase
同源超家族 H-superfamily homologous superfamily10 — Chloramphenicol acetyltransferase-like domain
结构域编号 domain_id1l5aB02
类 Class class6 — Special
架构 Architecture architecture10 — Helix non-globular
拓扑 Topology topology250 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
同源超家族 H-superfamily homologous superfamily80 —
结构域编号 domain_id1l5aB03
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology559 — Chloramphenicol Acetyltransferase
同源超家族 H-superfamily homologous superfamily30 — Nonribosomal peptide synthetase, condensation domain
结构域编号 domain_id1l5aC01
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology559 — Chloramphenicol Acetyltransferase
同源超家族 H-superfamily homologous superfamily10 — Chloramphenicol acetyltransferase-like domain
结构域编号 domain_id1l5aC02
类 Class class6 — Special
架构 Architecture architecture10 — Helix non-globular
拓扑 Topology topology250 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
同源超家族 H-superfamily homologous superfamily80 —
结构域编号 domain_id1l5aC03
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology559 — Chloramphenicol Acetyltransferase
同源超家族 H-superfamily homologous superfamily30 — Nonribosomal peptide synthetase, condensation domain
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7. 引用文献 (1)