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1loo

Crystal Structure of the Mouse-Muscle Adenylosuccinate Synthetase Ligated with GTP

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

adenylosuccinate synthetase

Mus musculus

UniProt P28650

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein homooligomer Homooligomer Protein 2 GUANOSINE-5'-TRIPHOSPHATE × 2 water × 2 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer
1iwe 1j4b 1lny 1lon 1loo 1mez 1mf0 1mf1 2dgn

9 assemblies

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex

None

View Construct and Data Evidence
UniProt name PURA1_MOUSE
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–457； UniProt 1–457

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id1loo
Deposition date deposition_date2002-05-06
Structure title titleCrystal Structure of the Mouse-Muscle Adenylosuccinate Synthetase Ligated with GTP
Keywords keywordsPurine biosynthesis, Ligase, GTP-binding; LIGASE
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

1loo__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

1loo__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

1loo__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）28.06 Å
Rg (electron density)27.15 Å
Total Rg27.94 Å
Atom count6770
Residues862
Excluded volume120380 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 1loo__assembly_1__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

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6. Fold Classification (SCOP + CATH) 4 domains

SCOP 2.08 (1 domains)

Domain ID domain_idd1looa_
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.37 — P-loop containing nucleoside triphosphate hydrolases
Superfamily Superfamily superfamilyc.37.1 — P-loop containing nucleoside triphosphate hydrolases
Family Family familyc.37.1.10 — Nitrogenase iron protein-like

CATH v4.4 (3 domains)

Domain ID domain_id1looA01
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology440 — Adenylosuccinate Synthetase; Chain A, domain 1
Homologous superfamily homologous superfamily10 — Adenylosuccinate Synthetase, subunit A, domain 1
Domain ID domain_id1looA02
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology300 — Adenylosuccinate Synthetase, subunit A; domain 2
Homologous superfamily homologous superfamily10 — Adenylosuccinate Synthetase, subunit A, domain 2
Domain ID domain_id1looA03
Class class3 — Alpha Beta
Architecture architecture90 — Alpha-Beta Complex
Topology topology170 — Adenylosuccinate Synthetase; Chain A, domain 3
Homologous superfamily homologous superfamily10 — Adenylosuccinate Synthetase, subunit A, domain 3
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7. Citations (1)