1m3d

Structure of Type IV Collagen NC1 Domains

Method: X-RAY DIFFRACTION

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1. 蛋白身份与相关结构 Protein Identity & Related Structures

Type IV Collagen Noncollagenous Domain- Alpha1

物种未注明

当前结构中的状态

Assembly	物理组成	蛋白状态	分子拷贝数	共同组分	数据核对
1	蛋白异源复合物	异源复合物	蛋白 6	Type IV Collagen Noncollagenous Domain- Alpha2 × 2 （Q7SIB3） BROMIDE ION × 18 GLYCEROL × 4 LUTETIUM (III) ION × 2 water × 6	与蛋白数一致
2	蛋白异源复合物	异源复合物	蛋白 6	Type IV Collagen Noncollagenous Domain- Alpha2 × 2 （Q7SIB3） BROMIDE ION × 18 GLYCEROL × 4 LUTETIUM (III) ION × 2 water × 6	与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据

UniProt名称	Q7SIB2_BOVIN
Isoform	—
PDB实体	1
链与序列区间	作者链 A； PDB构建体 1–229； UniProt 1–229 作者链 B； PDB构建体 1–229； UniProt 1–229 作者链 D； PDB构建体 1–229； UniProt 1–229 作者链 E； PDB构建体 1–229； UniProt 1–229 作者链 G； PDB构建体 1–229； UniProt 1–229 作者链 H； PDB构建体 1–229； UniProt 1–229 作者链 J； PDB构建体 1–229； UniProt 1–229 作者链 K； PDB构建体 1–229； UniProt 1–229

Type IV Collagen Noncollagenous Domain- Alpha2

物种未注明

UniProt Q7SIB3

当前结构中的状态

Assembly	物理组成	蛋白状态	分子拷贝数	共同组分	数据核对
1	蛋白异源复合物	异源复合物	蛋白 6	Type IV Collagen Noncollagenous Domain- Alpha1 × 4 （Q7SIB2） BROMIDE ION × 18 GLYCEROL × 4 LUTETIUM (III) ION × 2 water × 6	与蛋白数一致
2	蛋白异源复合物	异源复合物	蛋白 6	Type IV Collagen Noncollagenous Domain- Alpha1 × 4 （Q7SIB2） BROMIDE ION × 18 GLYCEROL × 4 LUTETIUM (III) ION × 2 water × 6	与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据

UniProt名称	Q7SIB3_BOVIN
Isoform	—
PDB实体	2
链与序列区间	作者链 C； PDB构建体 1–227； UniProt 1–227 作者链 F； PDB构建体 1–227； UniProt 1–227 作者链 I； PDB构建体 1–227； UniProt 1–227 作者链 L； PDB构建体 1–227； UniProt 1–227

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。

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2. 结构基本信息 2. Structure Basics

条目编号 entry_id	1m3d
沉积日期 deposition_date	2002-06-27
结构标题 title	Structure of Type IV Collagen NC1 Domains
关键词 keywords	Basement membrane, Type IV collagen, NC1 domain, Network assembly, 3D domain swapping, Br-MAD, STRUCTURAL PROTEIN; STRUCTURAL PROTEIN
实验方法 method	X-RAY DIFFRACTION

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3. Official assembly/model 理论 SAXS Official SAXS Profiles

页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。

1m3d__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

下载该曲线 .dat

1m3d__assembly_1__model_1 | I(q)

100 个绘图点；横轴和纵轴均采用对数尺度。

1m3d__assembly_1__model_1 | P(r) · Pending

P(r) 将按相同 assembly/model 分别计算和展示。

Rg（Guinier）	30.52 Å
Rg（电子密度）	29.74 Å
总 Rg	30.59 Å
原子数	10423
残基数	1341
排除体积	184350 Å³
最大 q	0.500 Å⁻¹

Assembly	Model	结构单元	聚集说明	状态	CRYSOL	操作
1	1	`1m3d__assembly_1__model_1`	hexameric （6）	成功	4.1.3-1-20251215 (887e7ef)	查看下载
2	1	`1m3d__assembly_2__model_1`	hexameric （6）	成功	4.1.3-1-20251215 (887e7ef)	查看下载

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4. 晶体学与实验 4. Crystallography & Experiment

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5. 实体与聚合物信息 Entities & Polymers (6)

实体 1 Entity 1 polymer

描述 description	Type IV Collagen Noncollagenous Domain- Alpha1
分子量 formula_weight	25399.9 kDa
来源方法 src_method	nat
拷贝数 entity_count	8

聚合物 Polymer

聚合物类型 type	polypeptide(L)
链编号 strand_id	A,B,D,E,G,H,J,K
原子数 atom_count	22023

SVDHGFLVTRHSQTTDDPQCPPGTKILYHGYSLLYVQGNERAHGQDLGTAGSCLRKFSTMPFLFCNINNVCNFASRNDYSYWLSTPEPMPMSMAPITGENIRPFISRCAVCEAPAMVMAVHSQTIQIPQCPTGWSSLWIGYSFVMHTSAGAEGSGQALASPGSCLEEFRSAPFIECHGRGTCNYYANAYSFWLATIERSEMFKKPTPSTLKAGELRTHVSRCQVCMRRT

实体 2 Entity 2 polymer

描述 description	Type IV Collagen Noncollagenous Domain- Alpha2
分子量 formula_weight	25083.5 kDa
来源方法 src_method	nat
拷贝数 entity_count	4

聚合物 Polymer

聚合物类型 type	polypeptide(L)
链编号 strand_id	C,F,I,L

ISIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDVCYYASRNDKSYWLSTTAPLPMMPVAEEDIRPYISRCSVCEAPAVAIAVHSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGARGTCHYYANKYSFWLTTIPEQSFQGTPSADTLKAGLIRTHISRCQVCMKNL

实体 3 Entity 3 non-polymer

描述 description	BROMIDE ION
分子量 formula_weight	79.9 kDa
来源方法 src_method	syn
拷贝数 entity_count	36

实体 4 Entity 4 non-polymer

描述 description	GLYCEROL
分子量 formula_weight	92.1 kDa
来源方法 src_method	syn
拷贝数 entity_count	8

实体 5 Entity 5 non-polymer

描述 description	LUTETIUM (III) ION
分子量 formula_weight	175.0 kDa
来源方法 src_method	syn
拷贝数 entity_count	4

实体 6 Entity 6 water

描述 description	water
分子量 formula_weight	18.0 kDa
来源方法 src_method	nat
拷贝数 entity_count	1138

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6. 折叠分类 (SCOP + CATH) 36 domains

SCOP 2.08 (24 domains)

结构域编号 domain_id	d1m3da1
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.169 — C-type lectin-like
超家族 Superfamily superfamily	d.169.1 — C-type lectin-like
家族 Family family	d.169.1.6 — Noncollagenous (NC1) domain of collagen IV

结构域编号 domain_id	d1m3da2
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.169 — C-type lectin-like
超家族 Superfamily superfamily	d.169.1 — C-type lectin-like
家族 Family family	d.169.1.6 — Noncollagenous (NC1) domain of collagen IV

结构域编号 domain_id	d1m3db1
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.169 — C-type lectin-like
超家族 Superfamily superfamily	d.169.1 — C-type lectin-like
家族 Family family	d.169.1.6 — Noncollagenous (NC1) domain of collagen IV

结构域编号 domain_id	d1m3db2
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.169 — C-type lectin-like
超家族 Superfamily superfamily	d.169.1 — C-type lectin-like
家族 Family family	d.169.1.6 — Noncollagenous (NC1) domain of collagen IV

结构域编号 domain_id	d1m3dc1
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.169 — C-type lectin-like
超家族 Superfamily superfamily	d.169.1 — C-type lectin-like
家族 Family family	d.169.1.6 — Noncollagenous (NC1) domain of collagen IV

结构域编号 domain_id	d1m3dc2
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.169 — C-type lectin-like
超家族 Superfamily superfamily	d.169.1 — C-type lectin-like
家族 Family family	d.169.1.6 — Noncollagenous (NC1) domain of collagen IV

结构域编号 domain_id	d1m3dd1
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.169 — C-type lectin-like
超家族 Superfamily superfamily	d.169.1 — C-type lectin-like
家族 Family family	d.169.1.6 — Noncollagenous (NC1) domain of collagen IV

结构域编号 domain_id	d1m3dd2
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.169 — C-type lectin-like
超家族 Superfamily superfamily	d.169.1 — C-type lectin-like
家族 Family family	d.169.1.6 — Noncollagenous (NC1) domain of collagen IV

结构域编号 domain_id	d1m3de1
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.169 — C-type lectin-like
超家族 Superfamily superfamily	d.169.1 — C-type lectin-like
家族 Family family	d.169.1.6 — Noncollagenous (NC1) domain of collagen IV

结构域编号 domain_id	d1m3de2
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.169 — C-type lectin-like
超家族 Superfamily superfamily	d.169.1 — C-type lectin-like
家族 Family family	d.169.1.6 — Noncollagenous (NC1) domain of collagen IV

结构域编号 domain_id	d1m3df1
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.169 — C-type lectin-like
超家族 Superfamily superfamily	d.169.1 — C-type lectin-like
家族 Family family	d.169.1.6 — Noncollagenous (NC1) domain of collagen IV

结构域编号 domain_id	d1m3df2
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.169 — C-type lectin-like
超家族 Superfamily superfamily	d.169.1 — C-type lectin-like
家族 Family family	d.169.1.6 — Noncollagenous (NC1) domain of collagen IV

结构域编号 domain_id	d1m3dg1
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.169 — C-type lectin-like
超家族 Superfamily superfamily	d.169.1 — C-type lectin-like
家族 Family family	d.169.1.6 — Noncollagenous (NC1) domain of collagen IV

结构域编号 domain_id	d1m3dg2
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.169 — C-type lectin-like
超家族 Superfamily superfamily	d.169.1 — C-type lectin-like
家族 Family family	d.169.1.6 — Noncollagenous (NC1) domain of collagen IV

结构域编号 domain_id	d1m3dh1
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.169 — C-type lectin-like
超家族 Superfamily superfamily	d.169.1 — C-type lectin-like
家族 Family family	d.169.1.6 — Noncollagenous (NC1) domain of collagen IV

结构域编号 domain_id	d1m3dh2
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.169 — C-type lectin-like
超家族 Superfamily superfamily	d.169.1 — C-type lectin-like
家族 Family family	d.169.1.6 — Noncollagenous (NC1) domain of collagen IV

结构域编号 domain_id	d1m3di1
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.169 — C-type lectin-like
超家族 Superfamily superfamily	d.169.1 — C-type lectin-like
家族 Family family	d.169.1.6 — Noncollagenous (NC1) domain of collagen IV

结构域编号 domain_id	d1m3di2
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.169 — C-type lectin-like
超家族 Superfamily superfamily	d.169.1 — C-type lectin-like
家族 Family family	d.169.1.6 — Noncollagenous (NC1) domain of collagen IV

结构域编号 domain_id	d1m3dj1
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.169 — C-type lectin-like
超家族 Superfamily superfamily	d.169.1 — C-type lectin-like
家族 Family family	d.169.1.6 — Noncollagenous (NC1) domain of collagen IV

结构域编号 domain_id	d1m3dj2
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.169 — C-type lectin-like
超家族 Superfamily superfamily	d.169.1 — C-type lectin-like
家族 Family family	d.169.1.6 — Noncollagenous (NC1) domain of collagen IV

结构域编号 domain_id	d1m3dk1
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.169 — C-type lectin-like
超家族 Superfamily superfamily	d.169.1 — C-type lectin-like
家族 Family family	d.169.1.6 — Noncollagenous (NC1) domain of collagen IV

结构域编号 domain_id	d1m3dk2
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.169 — C-type lectin-like
超家族 Superfamily superfamily	d.169.1 — C-type lectin-like
家族 Family family	d.169.1.6 — Noncollagenous (NC1) domain of collagen IV

结构域编号 domain_id	d1m3dl1
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.169 — C-type lectin-like
超家族 Superfamily superfamily	d.169.1 — C-type lectin-like
家族 Family family	d.169.1.6 — Noncollagenous (NC1) domain of collagen IV

结构域编号 domain_id	d1m3dl2
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.169 — C-type lectin-like
超家族 Superfamily superfamily	d.169.1 — C-type lectin-like
家族 Family family	d.169.1.6 — Noncollagenous (NC1) domain of collagen IV

CATH v4.4 (12 domains)

结构域编号 domain_id	1m3dA00
类 Class class	2 — Mainly Beta
架构 Architecture architecture	170 — Beta Complex
拓扑 Topology topology	240 — Noncollagenous (NC1) domain of collagen IV
同源超家族 H-superfamily homologous superfamily	10 — Collagen IV, non-collagenous

结构域编号 domain_id	1m3dB00
类 Class class	2 — Mainly Beta
架构 Architecture architecture	170 — Beta Complex
拓扑 Topology topology	240 — Noncollagenous (NC1) domain of collagen IV
同源超家族 H-superfamily homologous superfamily	10 — Collagen IV, non-collagenous

结构域编号 domain_id	1m3dC00
类 Class class	2 — Mainly Beta
架构 Architecture architecture	170 — Beta Complex
拓扑 Topology topology	240 — Noncollagenous (NC1) domain of collagen IV
同源超家族 H-superfamily homologous superfamily	10 — Collagen IV, non-collagenous

结构域编号 domain_id	1m3dD00
类 Class class	2 — Mainly Beta
架构 Architecture architecture	170 — Beta Complex
拓扑 Topology topology	240 — Noncollagenous (NC1) domain of collagen IV
同源超家族 H-superfamily homologous superfamily	10 — Collagen IV, non-collagenous

结构域编号 domain_id	1m3dE00
类 Class class	2 — Mainly Beta
架构 Architecture architecture	170 — Beta Complex
拓扑 Topology topology	240 — Noncollagenous (NC1) domain of collagen IV
同源超家族 H-superfamily homologous superfamily	10 — Collagen IV, non-collagenous

结构域编号 domain_id	1m3dF00
类 Class class	2 — Mainly Beta
架构 Architecture architecture	170 — Beta Complex
拓扑 Topology topology	240 — Noncollagenous (NC1) domain of collagen IV
同源超家族 H-superfamily homologous superfamily	10 — Collagen IV, non-collagenous

结构域编号 domain_id	1m3dG00
类 Class class	2 — Mainly Beta
架构 Architecture architecture	170 — Beta Complex
拓扑 Topology topology	240 — Noncollagenous (NC1) domain of collagen IV
同源超家族 H-superfamily homologous superfamily	10 — Collagen IV, non-collagenous

结构域编号 domain_id	1m3dH00
类 Class class	2 — Mainly Beta
架构 Architecture architecture	170 — Beta Complex
拓扑 Topology topology	240 — Noncollagenous (NC1) domain of collagen IV
同源超家族 H-superfamily homologous superfamily	10 — Collagen IV, non-collagenous

结构域编号 domain_id	1m3dI00
类 Class class	2 — Mainly Beta
架构 Architecture architecture	170 — Beta Complex
拓扑 Topology topology	240 — Noncollagenous (NC1) domain of collagen IV
同源超家族 H-superfamily homologous superfamily	10 — Collagen IV, non-collagenous

结构域编号 domain_id	1m3dJ00
类 Class class	2 — Mainly Beta
架构 Architecture architecture	170 — Beta Complex
拓扑 Topology topology	240 — Noncollagenous (NC1) domain of collagen IV
同源超家族 H-superfamily homologous superfamily	10 — Collagen IV, non-collagenous

结构域编号 domain_id	1m3dK00
类 Class class	2 — Mainly Beta
架构 Architecture architecture	170 — Beta Complex
拓扑 Topology topology	240 — Noncollagenous (NC1) domain of collagen IV
同源超家族 H-superfamily homologous superfamily	10 — Collagen IV, non-collagenous

结构域编号 domain_id	1m3dL00
类 Class class	2 — Mainly Beta
架构 Architecture architecture	170 — Beta Complex
拓扑 Topology topology	240 — Noncollagenous (NC1) domain of collagen IV
同源超家族 H-superfamily homologous superfamily	10 — Collagen IV, non-collagenous

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晶胞边长 a length_a	80.069 Å
晶胞边长 b length_b	137.963 Å
晶胞边长 c length_c	127.131 Å
晶胞夹角 α angle_alpha	90.00 °
晶胞夹角 β angle_beta	90.31 °
晶胞夹角 γ angle_gamma	90.00 °
晶胞分子数 Z z_pdb	16

空间群 space_group	P 1 21 1
空间群编号 int_tables_number	4
晶系 crystal_system	—

分辨率 resolution	2.000 Å
最低分辨率 resolution_low	8.000 Å
R 因子 r_factor	0.1710
R_work r_work	0.1690
R_free r_free	0.1970

Structure of Type IV Collagen NC1 Domains

1. 蛋白身份与相关结构 Protein Identity & Related Structures

Type IV Collagen Noncollagenous Domain- Alpha1

当前结构中的状态

数据库中的同蛋白其他状态

Type IV Collagen Noncollagenous Domain- Alpha2

当前结构中的状态

数据库中的同蛋白其他状态

2. 结构基本信息 2. Structure Basics

3. Official assembly/model 理论 SAXS Official SAXS Profiles

1m3d__assembly_1__model_1

1m3d__assembly_1__model_1 | I(q)

1m3d__assembly_1__model_1 | P(r) · Pending

4. 晶体学与实验 4. Crystallography & Experiment

晶胞参数 Unit Cell

对称性 Symmetry

精修参数 Refinement

衍射实验 Diffraction

5. 实体与聚合物信息 Entities & Polymers (6)

实体 1 Entity 1 polymer

聚合物 Polymer

实体 2 Entity 2 polymer

聚合物 Polymer

实体 3 Entity 3 non-polymer

实体 4 Entity 4 non-polymer

实体 5 Entity 5 non-polymer

实体 6 Entity 6 water

6. 折叠分类 (SCOP + CATH) 36 domains

SCOP 2.08 (24 domains)

CATH v4.4 (12 domains)

7. 引用文献 (1)

Structure of Type IV Collagen NC1 Domains

1. 蛋白身份与相关结构 Protein Identity & Related Structures

Type IV Collagen Noncollagenous Domain- Alpha1

当前结构中的状态

数据库中的同蛋白其他状态

单体

同源二聚体

同源四聚体

其他同源多聚体

异源或核酸复合物

Type IV Collagen Noncollagenous Domain- Alpha2

当前结构中的状态

数据库中的同蛋白其他状态

单体

同源二聚体

同源四聚体

其他同源多聚体

异源或核酸复合物

2. 结构基本信息 2. Structure Basics

3. Official assembly/model 理论 SAXS Official SAXS Profiles

1m3d__assembly_1__model_1

1m3d__assembly_1__model_1 | I(q)

1m3d__assembly_1__model_1 | P(r) · Pending

4. 晶体学与实验 4. Crystallography & Experiment

晶胞参数 Unit Cell

对称性 Symmetry

精修参数 Refinement

衍射实验 Diffraction

5. 实体与聚合物信息 Entities & Polymers (6)

实体 1 Entity 1 polymer

聚合物 Polymer

实体 2 Entity 2 polymer

聚合物 Polymer

实体 3 Entity 3 non-polymer

实体 4 Entity 4 non-polymer

实体 5 Entity 5 non-polymer

实体 6 Entity 6 water

6. 折叠分类 (SCOP + CATH) 36 domains

SCOP 2.08 (24 domains)

CATH v4.4 (12 domains)

7. 引用文献 (1)