1n8y
Crystal structure of the extracellular region of rat HER2
1. 蛋白身份与相关结构 Protein Identity & Related Structures
当前条目没有可用的 UniProt 蛋白身份。
七张关系表仍保留该条目的 assembly 与组成信息，但缺少统一蛋白身份时，不能可靠建立跨 PDB 的同蛋白链接。
当前条目的 assembly 组成
| Assembly | 物理组成 | 蛋白状态 | 蛋白 / DNA / RNA / 其他聚合物 | 数据核对 |
|---|---|---|---|---|
| 1 | 其他组合 | 单体 | 1 / 0 / 0 / 2 | 与蛋白数一致 |
页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。
2. 结构基本信息 2. Structure Basics
| 条目编号 entry_id | 1n8y |
| 沉积日期 deposition_date | 2002-11-21 |
| 结构标题 title | Crystal structure of the extracellular region of rat HER2 |
| 关键词 keywords | tyrosin kinase receptor, cell surface receptor, TRANSFERASE; TRANSFERASE |
| 实验方法 method | X-RAY DIFFRACTION |
3. Official assembly/model 理论 SAXS Official SAXS Profiles
页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。
1n8y__assembly_1__model_1
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
1n8y__assembly_1__model_1 | I(q)
1n8y__assembly_1__model_1 | P(r) · Pending
| Rg（Guinier） | 32.73 Å |
| Rg（电子密度） | 32.66 Å |
| 总 Rg | 33.08 Å |
| 原子数 | 4648 |
| 残基数 | 592 |
| 排除体积 | 81792 ų |
| 最大 q | 0.500 Å⁻¹ |
4. 晶体学与实验 4. Crystallography & Experiment
5. 实体与聚合物信息 Entities & Polymers (4)
6. 折叠分类 (SCOP + CATH) 8 domains
SCOP 2.08 (4 domains)
| 结构域编号 domain_id | d1n8yc1 |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.10 — Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) |
| 超家族 Superfamily superfamily | c.10.2 — L domain-like |
| 家族 Family family | c.10.2.5 — L domain |
| 结构域编号 domain_id | d1n8yc2 |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.10 — Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) |
| 超家族 Superfamily superfamily | c.10.2 — L domain-like |
| 家族 Family family | c.10.2.5 — L domain |
| 结构域编号 domain_id | d1n8yc3 |
| 类 Class class | g — Small proteins |
| 折叠类型 Fold fold | g.3 — Knottins (small inhibitors, toxins, lectins) |
| 超家族 Superfamily superfamily | g.3.9 — Growth factor receptor domain |
| 家族 Family family | g.3.9.1 — Growth factor receptor domain |
| 结构域编号 domain_id | d1n8yc4 |
| 类 Class class | g — Small proteins |
| 折叠类型 Fold fold | g.3 — Knottins (small inhibitors, toxins, lectins) |
| 超家族 Superfamily superfamily | g.3.9 — Growth factor receptor domain |
| 家族 Family family | g.3.9.1 — Growth factor receptor domain |
CATH v4.4 (4 domains)
| 结构域编号 domain_id | 1n8yC01 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 80 — Alpha-Beta Horseshoe |
| 拓扑 Topology topology | 20 — 24 nucleotide stem-loop, u2 snrnp hairpin iv. U2 a'; Chain A |
| 同源超家族 H-superfamily homologous superfamily | 20 — Receptor L-domain |
| 结构域编号 domain_id | 1n8yC02 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 10 — Ribbon |
| 拓扑 Topology topology | 220 — Hormone Receptor, Insulin-like Growth Factor Receptor 1; Chain A domain 2 |
| 同源超家族 H-superfamily homologous superfamily | 10 — Hormone Receptor, Insulin-like Growth Factor Receptor 1; Chain A, domain 2 |
| 结构域编号 domain_id | 1n8yC03 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 80 — Alpha-Beta Horseshoe |
| 拓扑 Topology topology | 20 — 24 nucleotide stem-loop, u2 snrnp hairpin iv. U2 a'; Chain A |
| 同源超家族 H-superfamily homologous superfamily | 20 — Receptor L-domain |
| 结构域编号 domain_id | 1n8yC04 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 10 — Ribbon |
| 拓扑 Topology topology | 220 — Hormone Receptor, Insulin-like Growth Factor Receptor 1; Chain A domain 2 |
| 同源超家族 H-superfamily homologous superfamily | 10 — Hormone Receptor, Insulin-like Growth Factor Receptor 1; Chain A, domain 2 |