1ny6

Crystal structure of sigm54 activator (AAA+ ATPase) in the active state

Method: X-RAY DIFFRACTION D_max: 165.0 Å Quality: GOOD

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1. 蛋白身份与相关结构 Protein Identity & Related Structures

transcriptional regulator (NtrC family)

Aquifex aeolicus

当前结构中的状态

Assembly	聚集状态	构建体	突变与修饰	配体、离子与共同组分	实验方法与环境	结构质量
1	蛋白同源多聚体同源多聚体蛋白 × 7 PDB 声明：heptameric（7）与蛋白拷贝数一致	链 A； UniProt 122–387 链 B； UniProt 122–387 链 C； UniProt 122–387 链 D； UniProt 122–387 链 E； UniProt 122–387 链 F； UniProt 122–387 链 G； UniProt 122–387	片段：residues 122-387	ADP ADENOSINE-5'-DIPHOSPHATE × 7	X-RAY DIFFRACTION X-ray结晶条件：VAPOR DIFFUSION, HANGING DROP；pH 6.5；298 K；diammonium tartrate, PEG 3350, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 298.0K	分辨率 3.10 Å R-free 0.329
2	蛋白同源多聚体同源多聚体蛋白 × 7 PDB 声明：heptameric（7）与蛋白拷贝数一致	链 H； UniProt 122–387 链 I； UniProt 122–387 链 J； UniProt 122–387 链 K； UniProt 122–387 链 L； UniProt 122–387 链 M； UniProt 122–387 链 N； UniProt 122–387	片段：residues 122-387	ADP ADENOSINE-5'-DIPHOSPHATE × 7	X-RAY DIFFRACTION X-ray结晶条件：VAPOR DIFFUSION, HANGING DROP；pH 6.5；298 K；diammonium tartrate, PEG 3350, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 298.0K	分辨率 3.10 Å R-free 0.329

数据库中的同蛋白其他状态

以下每一行都是同一 UniProt 蛋白在另一个 PDB 条目中的 biological assembly， “相对当前条目”直接指出证据层面的不同；没有差异标签表示当前已读取字段一致。

其他 PDB	相对当前条目 1NY6	Assembly / 聚集状态	构建体	突变与修饰	配体、离子与非聚合物	实验方法与环境	结构质量
1NY5 Crystal structure of sigm54 activator (AAA+ ATPase) in the inactive state 提交 2003-02-11	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白同源多聚体同源多聚体；蛋白 × 2 PDB 声明：dimeric	链 A 1–387（387 aa）片段：Regulatory and Central domain 链 B 1–387（387 aa）片段：Regulatory and Central domain	未记录	MG MAGNESIUM ION × 1 PO4 PHOSPHATE ION × 4 ADP ADENOSINE-5'-DIPHOSPHATE × 2 GOL GLYCEROL × 2	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 6.5；298 K；sodium/potasium phosphate, citric acid,imidazole,methanol,glycerol,, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 298.0K	分辨率 2.40 Å R-free 0.257
1ZY2 Crystal structure of the phosphorylated receiver domain of the transcription regulator NtrC1 from Aquifex aeolicus 提交 2005-06-09	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白同源多聚体同源多聚体；蛋白 × 2 PDB 声明：dimeric	链 A 1–136（136 aa）链 B 1–136（136 aa）	非标准单体：是（mmCIF未提供具体位点）非标准单体：是（mmCIF未提供具体位点）	MG MAGNESIUM ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 5.5；310 K；PEG-3350, AMMONIUM CHLORIDE, GLYCEROL, CITRIC ACID, pH 5.5, VAPOR DIFFUSION, HANGING DROP, temperature 310K	分辨率 3.03 Å R-free 0.283
3M0E Crystal structure of the ATP-bound state of Walker B mutant of NtrC1 ATPase domain 提交 2010-03-02	构建体不同突变/修饰不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白同源多聚体同源多聚体；蛋白 × 7 PDB 声明：heptameric	链 A 122–387（266 aa）片段：ATP-ase domain 链 B 122–387（266 aa）片段：ATP-ase domain 链 C 122–387（266 aa）片段：ATP-ase domain 链 D 122–387（266 aa）片段：ATP-ase domain 链 E 122–387（266 aa）片段：ATP-ase domain 链 F 122–387（266 aa）片段：ATP-ase domain 链 G 122–387（266 aa）片段：ATP-ase domain	突变：E239A 突变：E239A 突变：E239A 突变：E239A 突变：E239A 突变：E239A 突变：E239A	ATP ADENOSINE-5'-TRIPHOSPHATE × 7 MG MAGNESIUM ION × 7	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 5.5；277 K；0.1 M SODIUM CITRATE, 0.01 M FECL3, 0-5% (V/V) JEFFAMINE M-600, pH 5.5, VAPOR DIFFUSION, HANGING DROP, temperature 277K	分辨率 2.63 Å R-free 0.241
4BT0 MuB is an AAAplus ATPase that forms helical filaments to control target selection for DNA transposition 提交 2013-06-12	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验方法不同实验环境不同结构质量不同	Assembly 1 蛋白同源多聚体同源多聚体；蛋白 × 14 PDB 声明：helical	链 A 312–384（73 aa）片段：AAAPLUS DOMAIN, RESIDUES 312-384 链 B 137–309（173 aa）片段：AAAPLUS DOMAIN, RESIDUES 137-309	未记录	ADP ADENOSINE-5'-DIPHOSPHATE × 14	ELECTRON MICROSCOPY cryo-EM缓冲液 30 MM TRISHCL PH 8.0, 0.3 M KCL, 5MM MGCL2, 1MM DTT, 1 MM ATP OR ATP-GAMMA-S；pH 8；30 MM TRISHCL PH 8.0, 0.3 M KCL, 5MM MGCL2, 1MM DTT, 1 MM ATP OR ATP-GAMMA-S cryo-EM玻璃化条件冷冻剂 ETHANE；LIQUID ETHANE	分辨率 17.00 Å
4BT0 MuB is an AAAplus ATPase that forms helical filaments to control target selection for DNA transposition 提交 2013-06-12	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验方法不同实验环境不同结构质量不同	Assembly 2 蛋白同源多聚体同源多聚体；蛋白 × 2 PDB 声明：dimeric	链 A 312–384（73 aa）片段：AAAPLUS DOMAIN, RESIDUES 312-384 链 B 137–309（173 aa）片段：AAAPLUS DOMAIN, RESIDUES 137-309	未记录	ADP ADENOSINE-5'-DIPHOSPHATE × 2	ELECTRON MICROSCOPY cryo-EM缓冲液 30 MM TRISHCL PH 8.0, 0.3 M KCL, 5MM MGCL2, 1MM DTT, 1 MM ATP OR ATP-GAMMA-S；pH 8；30 MM TRISHCL PH 8.0, 0.3 M KCL, 5MM MGCL2, 1MM DTT, 1 MM ATP OR ATP-GAMMA-S cryo-EM玻璃化条件冷冻剂 ETHANE；LIQUID ETHANE	分辨率 17.00 Å
4BT0 MuB is an AAAplus ATPase that forms helical filaments to control target selection for DNA transposition 提交 2013-06-12	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验方法不同实验环境不同结构质量不同	Assembly 3 蛋白同源多聚体同源多聚体；蛋白 × 2 PDB 声明：dimeric	链 A 312–384（73 aa）片段：AAAPLUS DOMAIN, RESIDUES 312-384 链 B 137–309（173 aa）片段：AAAPLUS DOMAIN, RESIDUES 137-309	未记录	ADP ADENOSINE-5'-DIPHOSPHATE × 2	ELECTRON MICROSCOPY cryo-EM缓冲液 30 MM TRISHCL PH 8.0, 0.3 M KCL, 5MM MGCL2, 1MM DTT, 1 MM ATP OR ATP-GAMMA-S；pH 8；30 MM TRISHCL PH 8.0, 0.3 M KCL, 5MM MGCL2, 1MM DTT, 1 MM ATP OR ATP-GAMMA-S cryo-EM玻璃化条件冷冻剂 ETHANE；LIQUID ETHANE	分辨率 17.00 Å
4BT1 MuB is an AAAplus ATPase that forms helical filaments to control target selection for DNA transposition 提交 2013-06-12	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验方法不同实验环境不同结构质量不同	Assembly 1 蛋白同源多聚体同源多聚体；蛋白 × 14 PDB 声明：helical	链 A 312–384（73 aa）片段：AAAPLUS DOMAIN, RESIDUES 312-384 链 B 137–309（173 aa）片段：AAAPLUS DOMAIN, RESIDUES 137-309	未记录	ADP ADENOSINE-5'-DIPHOSPHATE × 14	ELECTRON MICROSCOPY cryo-EM缓冲液 30 MM TRISHCL PH 8.0, 0.3 M KCL, 5MM MGCL2, 1MM DTT, 1 MM ATP OR ATP-GAMMA-S；pH 8；30 MM TRISHCL PH 8.0, 0.3 M KCL, 5MM MGCL2, 1MM DTT, 1 MM ATP OR ATP-GAMMA-S cryo-EM玻璃化条件冷冻剂 ETHANE；LIQUID ETHANE	分辨率 16.00 Å
4BT1 MuB is an AAAplus ATPase that forms helical filaments to control target selection for DNA transposition 提交 2013-06-12	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验方法不同实验环境不同结构质量不同	Assembly 2 蛋白同源多聚体同源多聚体；蛋白 × 2 PDB 声明：dimeric	链 A 312–384（73 aa）片段：AAAPLUS DOMAIN, RESIDUES 312-384 链 B 137–309（173 aa）片段：AAAPLUS DOMAIN, RESIDUES 137-309	未记录	ADP ADENOSINE-5'-DIPHOSPHATE × 2	ELECTRON MICROSCOPY cryo-EM缓冲液 30 MM TRISHCL PH 8.0, 0.3 M KCL, 5MM MGCL2, 1MM DTT, 1 MM ATP OR ATP-GAMMA-S；pH 8；30 MM TRISHCL PH 8.0, 0.3 M KCL, 5MM MGCL2, 1MM DTT, 1 MM ATP OR ATP-GAMMA-S cryo-EM玻璃化条件冷冻剂 ETHANE；LIQUID ETHANE	分辨率 16.00 Å
4BT1 MuB is an AAAplus ATPase that forms helical filaments to control target selection for DNA transposition 提交 2013-06-12	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验方法不同实验环境不同结构质量不同	Assembly 3 蛋白同源多聚体同源多聚体；蛋白 × 2 PDB 声明：dimeric	链 A 312–384（73 aa）片段：AAAPLUS DOMAIN, RESIDUES 312-384 链 B 137–309（173 aa）片段：AAAPLUS DOMAIN, RESIDUES 137-309	未记录	ADP ADENOSINE-5'-DIPHOSPHATE × 2	ELECTRON MICROSCOPY cryo-EM缓冲液 30 MM TRISHCL PH 8.0, 0.3 M KCL, 5MM MGCL2, 1MM DTT, 1 MM ATP OR ATP-GAMMA-S；pH 8；30 MM TRISHCL PH 8.0, 0.3 M KCL, 5MM MGCL2, 1MM DTT, 1 MM ATP OR ATP-GAMMA-S cryo-EM玻璃化条件冷冻剂 ETHANE；LIQUID ETHANE	分辨率 16.00 Å
4L4U Crystal structure of construct containing A. aeolicus NtrC1 receiver, central and DNA binding domains 提交 2013-06-09	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白同源多聚体同源多聚体；蛋白 × 2 PDB 声明：dimeric	链 A 1–439（439 aa）	未记录	未记录非水小分子	X-RAY DIFFRACTION mmCIF 未提供已读取条件	分辨率 2.20 Å R-free 0.248
4L5E Crystal structure of A. aeolicus NtrC1 DNA binding domain 提交 2013-06-10	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白同源多聚体同源多聚体；蛋白 × 2 PDB 声明：dimeric	链 A 393–438（46 aa）片段：unp residues 393-438	未记录	SO4 SULFATE ION × 4	X-RAY DIFFRACTION mmCIF 未提供已读取条件	分辨率 1.34 Å R-free 0.206
4LY6 Nucleotide-induced asymmetry within ATPase activator ring drives s54-RNAP interaction and ATP hydrolysis 提交 2013-07-30	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白同源多聚体同源多聚体；蛋白 × 6 PDB 声明：hexameric	链 A 121–387（267 aa）片段：UNP residues 121-387 链 B 121–387（267 aa）片段：UNP residues 121-387 链 C 121–387（267 aa）片段：UNP residues 121-387 链 D 121–387（267 aa）片段：UNP residues 121-387 链 E 121–387（267 aa）片段：UNP residues 121-387 链 F 121–387（267 aa）片段：UNP residues 121-387	未记录	08T [[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-tris(fluoranyl)beryllium × 5 MG MAGNESIUM ION × 5	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7.9；277 K；20% ethylene glycol, pH 7.9, vapor diffusion, hanging drop, temperature 277K	分辨率 3.60 Å R-free 0.308
4LY6 Nucleotide-induced asymmetry within ATPase activator ring drives s54-RNAP interaction and ATP hydrolysis 提交 2013-07-30	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 2 蛋白同源多聚体同源多聚体；蛋白 × 6 PDB 声明：hexameric	链 G 121–387（267 aa）片段：UNP residues 121-387 链 H 121–387（267 aa）片段：UNP residues 121-387 链 I 121–387（267 aa）片段：UNP residues 121-387 链 J 121–387（267 aa）片段：UNP residues 121-387 链 K 121–387（267 aa）片段：UNP residues 121-387 链 L 121–387（267 aa）片段：UNP residues 121-387	未记录	08T [[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-tris(fluoranyl)beryllium × 5 MG MAGNESIUM ION × 5 ADP ADENOSINE-5'-DIPHOSPHATE × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7.9；277 K；20% ethylene glycol, pH 7.9, vapor diffusion, hanging drop, temperature 277K	分辨率 3.60 Å R-free 0.308
4LY6 Nucleotide-induced asymmetry within ATPase activator ring drives s54-RNAP interaction and ATP hydrolysis 提交 2013-07-30	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 3 蛋白同源多聚体同源多聚体；蛋白 × 6 PDB 声明：hexameric	链 M 121–387（267 aa）片段：UNP residues 121-387 链 N 121–387（267 aa）片段：UNP residues 121-387 链 O 121–387（267 aa）片段：UNP residues 121-387 链 P 121–387（267 aa）片段：UNP residues 121-387 链 Q 121–387（267 aa）片段：UNP residues 121-387 链 R 121–387（267 aa）片段：UNP residues 121-387	未记录	08T [[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-tris(fluoranyl)beryllium × 5 MG MAGNESIUM ION × 5	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7.9；277 K；20% ethylene glycol, pH 7.9, vapor diffusion, hanging drop, temperature 277K	分辨率 3.60 Å R-free 0.308
4LY6 Nucleotide-induced asymmetry within ATPase activator ring drives s54-RNAP interaction and ATP hydrolysis 提交 2013-07-30	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 4 蛋白同源多聚体同源多聚体；蛋白 × 6 PDB 声明：hexameric	链 S 121–387（267 aa）片段：UNP residues 121-387 链 T 121–387（267 aa）片段：UNP residues 121-387 链 U 121–387（267 aa）片段：UNP residues 121-387 链 V 121–387（267 aa）片段：UNP residues 121-387 链 W 121–387（267 aa）片段：UNP residues 121-387 链 X 121–387（267 aa）片段：UNP residues 121-387	未记录	08T [[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-tris(fluoranyl)beryllium × 5 MG MAGNESIUM ION × 5 ADP ADENOSINE-5'-DIPHOSPHATE × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7.9；277 K；20% ethylene glycol, pH 7.9, vapor diffusion, hanging drop, temperature 277K	分辨率 3.60 Å R-free 0.308
4LZZ Nucleotide-induced asymmetry within atpase activator ring drives s54-RNAP interaction and ATP hydrolysis 提交 2013-08-01	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白同源多聚体同源多聚体；蛋白 × 6 PDB 声明：hexameric	链 A 121–387（267 aa）片段：ATPase Domain (UNP residues 121-387) 链 B 121–387（267 aa）片段：ATPase Domain (UNP residues 121-387) 链 C 121–387（267 aa）片段：ATPase Domain (UNP residues 121-387) 链 D 121–387（267 aa）片段：ATPase Domain (UNP residues 121-387) 链 E 121–387（267 aa）片段：ATPase Domain (UNP residues 121-387) 链 F 121–387（267 aa）片段：ATPase Domain (UNP residues 121-387)	未记录	08T [[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-tris(fluoranyl)beryllium × 5 MG MAGNESIUM ION × 6 ADP ADENOSINE-5'-DIPHOSPHATE × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7.9；277 K；20% ethylene glycol, crystal soaked in fresh mother liquor prior to flash cooling, pH 7.9, VAPOR DIFFUSION, HANGING DROP, temperature 277K	分辨率 3.21 Å R-free 0.322
4LZZ Nucleotide-induced asymmetry within atpase activator ring drives s54-RNAP interaction and ATP hydrolysis 提交 2013-08-01	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 2 蛋白同源多聚体同源多聚体；蛋白 × 6 PDB 声明：hexameric	链 G 121–387（267 aa）片段：ATPase Domain (UNP residues 121-387) 链 H 121–387（267 aa）片段：ATPase Domain (UNP residues 121-387) 链 I 121–387（267 aa）片段：ATPase Domain (UNP residues 121-387) 链 J 121–387（267 aa）片段：ATPase Domain (UNP residues 121-387) 链 K 121–387（267 aa）片段：ATPase Domain (UNP residues 121-387) 链 L 121–387（267 aa）片段：ATPase Domain (UNP residues 121-387)	未记录	08T [[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-tris(fluoranyl)beryllium × 5 MG MAGNESIUM ION × 6 ADP ADENOSINE-5'-DIPHOSPHATE × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7.9；277 K；20% ethylene glycol, crystal soaked in fresh mother liquor prior to flash cooling, pH 7.9, VAPOR DIFFUSION, HANGING DROP, temperature 277K	分辨率 3.21 Å R-free 0.322
4LZZ Nucleotide-induced asymmetry within atpase activator ring drives s54-RNAP interaction and ATP hydrolysis 提交 2013-08-01	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 3 蛋白同源多聚体同源多聚体；蛋白 × 6 PDB 声明：hexameric	链 M 121–387（267 aa）片段：ATPase Domain (UNP residues 121-387) 链 N 121–387（267 aa）片段：ATPase Domain (UNP residues 121-387) 链 O 121–387（267 aa）片段：ATPase Domain (UNP residues 121-387) 链 P 121–387（267 aa）片段：ATPase Domain (UNP residues 121-387) 链 Q 121–387（267 aa）片段：ATPase Domain (UNP residues 121-387) 链 R 121–387（267 aa）片段：ATPase Domain (UNP residues 121-387)	未记录	08T [[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-tris(fluoranyl)beryllium × 6 MG MAGNESIUM ION × 5	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7.9；277 K；20% ethylene glycol, crystal soaked in fresh mother liquor prior to flash cooling, pH 7.9, VAPOR DIFFUSION, HANGING DROP, temperature 277K	分辨率 3.21 Å R-free 0.322
4LZZ Nucleotide-induced asymmetry within atpase activator ring drives s54-RNAP interaction and ATP hydrolysis 提交 2013-08-01	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 4 蛋白同源多聚体同源多聚体；蛋白 × 6 PDB 声明：hexameric	链 S 121–387（267 aa）片段：ATPase Domain (UNP residues 121-387) 链 T 121–387（267 aa）片段：ATPase Domain (UNP residues 121-387) 链 U 121–387（267 aa）片段：ATPase Domain (UNP residues 121-387) 链 V 121–387（267 aa）片段：ATPase Domain (UNP residues 121-387) 链 W 121–387（267 aa）片段：ATPase Domain (UNP residues 121-387) 链 X 121–387（267 aa）片段：ATPase Domain (UNP residues 121-387)	未记录	08T [[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-tris(fluoranyl)beryllium × 6 MG MAGNESIUM ION × 6	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7.9；277 K；20% ethylene glycol, crystal soaked in fresh mother liquor prior to flash cooling, pH 7.9, VAPOR DIFFUSION, HANGING DROP, temperature 277K	分辨率 3.21 Å R-free 0.322
9MSE de novo SigN RNA polymerase transcription initiation intermediate with pre-catalytic bEBP state (RPi1 open ring) 提交 2025-01-09	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验方法不同实验环境不同结构质量不同	Assembly 1 蛋白–DNA 异源复合物；蛋白 × 12 PDB 声明：16-meric	链 A 121–387（267 aa）链 B 121–387（267 aa）链 C 121–387（267 aa）链 D 121–387（267 aa）链 E 121–387（267 aa）链 F 121–387（267 aa）	未记录	ATP ADENOSINE-5'-TRIPHOSPHATE × 6 MG MAGNESIUM ION × 3 POP PYROPHOSPHATE 2- × 1 ZN ZINC ION × 2	ELECTRON MICROSCOPY cryo-EM缓冲液 pH 8；40 mM Tris-HCl, pH 8/RT, 200 mM KCl, 10 mM MgCl2, 1 mM DTT; fluorinated fos-choline-8 (FC8F) added to a final concentration of 1.5 mM during grid preparation cryo-EM玻璃化条件冷冻剂 ETHANE	分辨率 2.70 Å
9MSF de novo SigN RNA polymerase transcription initiation intermediate with post-catalytic bEBP state (RPi1 closed ring) 提交 2025-01-09	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验方法不同实验环境不同结构质量不同	Assembly 1 蛋白–DNA 异源复合物；蛋白 × 12 PDB 声明：16-meric	链 A 121–387（267 aa）链 B 121–387（267 aa）链 C 121–387（267 aa）链 D 121–387（267 aa）链 E 121–387（267 aa）链 F 121–387（267 aa）	未记录	ATP ADENOSINE-5'-TRIPHOSPHATE × 5 MG MAGNESIUM ION × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 1 POP PYROPHOSPHATE 2- × 1 ZN ZINC ION × 2	ELECTRON MICROSCOPY cryo-EM缓冲液 pH 8；40 mM Tris-HCl, pH 8/RT, 200 mM KCl, 10 mM MgCl2, 1 mM DTT; fluorinated fos-choline-8 (FC8F) added to a final concentration of 1.5 mM during grid preparation cryo-EM玻璃化条件冷冻剂 ETHANE	分辨率 2.60 Å
9MSG De novo SigN RNA polymerase transcription initiation intermediate with bound SigN-RII 提交 2025-01-09	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验方法不同实验环境不同结构质量不同	Assembly 1 蛋白–DNA 异源复合物；蛋白 × 12 PDB 声明：tetradecameric	链 A 121–387（267 aa）链 B 121–387（267 aa）链 C 121–387（267 aa）链 D 121–387（267 aa）链 E 121–387（267 aa）链 F 121–387（267 aa）	未记录	ATP ADENOSINE-5'-TRIPHOSPHATE × 5 MG MAGNESIUM ION × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 1 POP PYROPHOSPHATE 2- × 1 ZN ZINC ION × 2	ELECTRON MICROSCOPY cryo-EM缓冲液 pH 8；40 mM Tris-HCl, pH 8/RT, 200 mM KCl, 10 mM MgCl2, 1 mM DTT; fluorinated fos-choline-8 (FC8F) added to a final concentration of 1.5 mM during grid preparation cryo-EM玻璃化条件冷冻剂 ETHANE	分辨率 2.70 Å

共 12 个其他 PDB 条目、22 个 assembly。打开独立比较页并筛选聚集状态

查看构建体与数据证据

UniProt名称	O67198_AQUAE
Isoform	—
PDB实体	1
链与序列区间	作者链 A； PDB构建体 1–267； UniProt 122–387 作者链 B； PDB构建体 1–267； UniProt 122–387 作者链 C； PDB构建体 1–267； UniProt 122–387 作者链 D； PDB构建体 1–267； UniProt 122–387 作者链 E； PDB构建体 1–267； UniProt 122–387 作者链 F； PDB构建体 1–267； UniProt 122–387 作者链 G； PDB构建体 1–267； UniProt 122–387 作者链 H； PDB构建体 1–267； UniProt 122–387 作者链 I； PDB构建体 1–267； UniProt 122–387 作者链 J； PDB构建体 1–267； UniProt 122–387 作者链 K； PDB构建体 1–267； UniProt 122–387 作者链 L； PDB构建体 1–267； UniProt 122–387 作者链 M； PDB构建体 1–267； UniProt 122–387 作者链 N； PDB构建体 1–267； UniProt 122–387

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。

SAXS 散射曲线 SAXS Profile

P(r) 距离分布 P(r) Distribution

下载 Download SAXS (.dat) P(r) (.pr.out) CIF

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2. 结构基本信息 2. Structure Basics

条目编号 entry_id	1ny6
沉积日期 deposition_date	2003-02-11
结构标题 title	Crystal structure of sigm54 activator (AAA+ ATPase) in the active state
关键词 keywords	AAA+ ATPase, sigma54 activator, bacterial transcription, heptamer, TRANSCRIPTION; TRANSCRIPTION
实验方法 method	X-RAY DIFFRACTION

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3. SAXS 参数 (CRYSOL 理论计算) 3. SAXS Parameters (CRYSOL)

回转半径 Rg (Guinier) rg_guinier	51.14 Å
回转半径 Rg (电子) rg_electron	50.74 Å
零角强度 I(0) i0	2094170000.00
分子量 molecular_weight	397740.0 kDa
排除体积 excluded_volume	504920 Å³
包络体积 envelope_volume	729420 Å³
水化壳体积 shell_volume	117870 Å³
包络直径 envelope_diameter	174.8 Å
壳层 Rg shell_rg	57.44 Å
包络 Rg envelope_rg	48.35 Å
形状 Rg shape_rg	50.72 Å
总 Rg total_rg	51.06 Å
总原子数 total_atoms	28041
残基数 n_residues	3456
球谐函数阶数 n_harmonics	20
q 范围 q_range	— – 0.5000 Å⁻¹
数据点数 n_points	101
壳层类型 shell_type	directional
溶剂电子密度 solvent_density	0.3340 e/Å³
壳层衬度 contrast_shell	0.0300 e/Å³
CRYSOL 版本 crysol_version	4.1.3

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4. P(r) 距离分布 (GNOM 反演) 4. P(r) Analysis (GNOM)

最大尺寸 Dmax dmax	165.0 Å
Rg (实空间) rg_real	50.95 Å
Rg 误差 (实空间) rg_real_error	1.38 Å
I(0) (实空间) i0_real	2.0940e+09
I(0) 误差 (实空间) i0_real_error	3.7810e+07
Rg (倒空间) rg_reciprocal	51.30 Å
I(0) (倒空间) i0_reciprocal	2095000000.0000
解质量估计 total_estimate	0.8719
解质量评级 solution_quality	GOOD a GOOD solution
P(r) 峰数 n_peaks	2
主峰位置 r_peak_primary	63.9 Å
偏度 Skewness skewness	0.169
峰度 Kurtosis kurtosis	-0.340
角度范围 angular_range	— – 0.1550 Å⁻¹
当前正则化参数 α current_alpha	0.0000
最高正则化参数 α highest_alpha	170200000.0000
实空间数据点数 n_real_points	32
GNOM 版本 gnom_version	4.1.3
质量判据 quality_criteria	AN1: 0.000; Oscil: 0.844; Stabil: 0.999; Sysdev: 1.000; Positv: 1.000; Valcen: 0.978; Smooth: 0.823

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5. 晶体学与实验 5. Crystallography & Experiment

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6. 实体与聚合物信息 Entities & Polymers (2)

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7. 折叠分类 (SCOP + CATH) 42 domains

SCOP 2.08 (14 domains)

结构域编号 domain_id	d1ny6a_
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamily	c.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family family	c.37.1.20 — Extended AAA-ATPase domain

结构域编号 domain_id	d1ny6b_
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamily	c.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family family	c.37.1.20 — Extended AAA-ATPase domain

结构域编号 domain_id	d1ny6c_
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamily	c.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family family	c.37.1.20 — Extended AAA-ATPase domain

结构域编号 domain_id	d1ny6d_
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamily	c.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family family	c.37.1.20 — Extended AAA-ATPase domain

结构域编号 domain_id	d1ny6e_
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamily	c.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family family	c.37.1.20 — Extended AAA-ATPase domain

结构域编号 domain_id	d1ny6f_
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamily	c.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family family	c.37.1.20 — Extended AAA-ATPase domain

结构域编号 domain_id	d1ny6g_
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamily	c.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family family	c.37.1.20 — Extended AAA-ATPase domain

结构域编号 domain_id	d1ny6h_
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamily	c.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family family	c.37.1.20 — Extended AAA-ATPase domain

结构域编号 domain_id	d1ny6i_
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamily	c.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family family	c.37.1.20 — Extended AAA-ATPase domain

结构域编号 domain_id	d1ny6j_
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamily	c.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family family	c.37.1.20 — Extended AAA-ATPase domain

结构域编号 domain_id	d1ny6k_
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamily	c.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family family	c.37.1.20 — Extended AAA-ATPase domain

结构域编号 domain_id	d1ny6l_
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamily	c.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family family	c.37.1.20 — Extended AAA-ATPase domain

结构域编号 domain_id	d1ny6m_
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamily	c.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family family	c.37.1.20 — Extended AAA-ATPase domain

结构域编号 domain_id	d1ny6n_
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamily	c.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family family	c.37.1.20 — Extended AAA-ATPase domain

CATH v4.4 (28 domains)

结构域编号 domain_id	1ny6A01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	300 — P-loop containing nucleotide triphosphate hydrolases

结构域编号 domain_id	1ny6A02
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	8 — Helicase, Ruva Protein; domain 3
同源超家族 H-superfamily homologous superfamily	60 —

结构域编号 domain_id	1ny6B01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	300 — P-loop containing nucleotide triphosphate hydrolases

结构域编号 domain_id	1ny6B02
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	8 — Helicase, Ruva Protein; domain 3
同源超家族 H-superfamily homologous superfamily	60 —

结构域编号 domain_id	1ny6C01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	300 — P-loop containing nucleotide triphosphate hydrolases

结构域编号 domain_id	1ny6C02
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	8 — Helicase, Ruva Protein; domain 3
同源超家族 H-superfamily homologous superfamily	60 —

结构域编号 domain_id	1ny6D01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	300 — P-loop containing nucleotide triphosphate hydrolases

结构域编号 domain_id	1ny6D02
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	8 — Helicase, Ruva Protein; domain 3
同源超家族 H-superfamily homologous superfamily	60 —

结构域编号 domain_id	1ny6E01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	300 — P-loop containing nucleotide triphosphate hydrolases

结构域编号 domain_id	1ny6E02
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	8 — Helicase, Ruva Protein; domain 3
同源超家族 H-superfamily homologous superfamily	60 —

结构域编号 domain_id	1ny6F01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	300 — P-loop containing nucleotide triphosphate hydrolases

结构域编号 domain_id	1ny6F02
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	8 — Helicase, Ruva Protein; domain 3
同源超家族 H-superfamily homologous superfamily	60 —

结构域编号 domain_id	1ny6G01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	300 — P-loop containing nucleotide triphosphate hydrolases

结构域编号 domain_id	1ny6G02
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	8 — Helicase, Ruva Protein; domain 3
同源超家族 H-superfamily homologous superfamily	60 —

结构域编号 domain_id	1ny6H01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	300 — P-loop containing nucleotide triphosphate hydrolases

结构域编号 domain_id	1ny6H02
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	8 — Helicase, Ruva Protein; domain 3
同源超家族 H-superfamily homologous superfamily	60 —

结构域编号 domain_id	1ny6I01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	300 — P-loop containing nucleotide triphosphate hydrolases

结构域编号 domain_id	1ny6I02
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	8 — Helicase, Ruva Protein; domain 3
同源超家族 H-superfamily homologous superfamily	60 —

结构域编号 domain_id	1ny6J01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	300 — P-loop containing nucleotide triphosphate hydrolases

结构域编号 domain_id	1ny6J02
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	8 — Helicase, Ruva Protein; domain 3
同源超家族 H-superfamily homologous superfamily	60 —

结构域编号 domain_id	1ny6K01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	300 — P-loop containing nucleotide triphosphate hydrolases

结构域编号 domain_id	1ny6K02
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	8 — Helicase, Ruva Protein; domain 3
同源超家族 H-superfamily homologous superfamily	60 —

结构域编号 domain_id	1ny6L01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	300 — P-loop containing nucleotide triphosphate hydrolases

结构域编号 domain_id	1ny6L02
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	8 — Helicase, Ruva Protein; domain 3
同源超家族 H-superfamily homologous superfamily	60 —

结构域编号 domain_id	1ny6M01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	300 — P-loop containing nucleotide triphosphate hydrolases

结构域编号 domain_id	1ny6M02
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	8 — Helicase, Ruva Protein; domain 3
同源超家族 H-superfamily homologous superfamily	60 —

结构域编号 domain_id	1ny6N01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	300 — P-loop containing nucleotide triphosphate hydrolases

结构域编号 domain_id	1ny6N02
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	8 — Helicase, Ruva Protein; domain 3
同源超家族 H-superfamily homologous superfamily	60 —

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8. 引用文献 (1)

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晶胞边长 a length_a	106.788 Å
晶胞边长 b length_b	108.265 Å
晶胞边长 c length_c	110.020 Å
晶胞夹角 α angle_alpha	70.25 °
晶胞夹角 β angle_beta	85.90 °
晶胞夹角 γ angle_gamma	73.27 °
晶胞分子数 Z z_pdb	14

空间群 space_group	P 1
空间群编号 int_tables_number	1
晶系 crystal_system	—

分辨率 resolution	3.100 Å
最低分辨率 resolution_low	19.980 Å
R 因子 r_factor	0.2660
R_work r_work	0.2660
R_free r_free	0.3290

描述 description	transcriptional regulator (NtrC family)
分子量 formula_weight	30618.4 kDa
来源方法 src_method	man
拷贝数 entity_count	14

聚合物类型 type	polypeptide(L)
链编号 strand_id	A,B,C,D,E,F,G,H,I,J,K,L,M,N
原子数 atom_count	28041

Crystal structure of sigm54 activator (AAA+ ATPase) in the active state

1. 蛋白身份与相关结构 Protein Identity & Related Structures

transcriptional regulator (NtrC family)

当前结构中的状态

数据库中的同蛋白其他状态

SAXS 散射曲线 SAXS Profile

P(r) 距离分布 P(r) Distribution

2. 结构基本信息 2. Structure Basics

3. SAXS 参数 (CRYSOL 理论计算) 3. SAXS Parameters (CRYSOL)

4. P(r) 距离分布 (GNOM 反演) 4. P(r) Analysis (GNOM)

5. 晶体学与实验 5. Crystallography & Experiment

晶胞参数 Unit Cell

对称性 Symmetry

精修参数 Refinement

衍射实验 Diffraction

6. 实体与聚合物信息 Entities & Polymers (2)

实体 1 Entity 1 polymer

聚合物 Polymer

来源 Source

实体 2 Entity 2 non-polymer

7. 折叠分类 (SCOP + CATH) 42 domains

SCOP 2.08 (14 domains)

CATH v4.4 (28 domains)

8. 引用文献 (1)

9. 文件与曲线 (10)

Files (7)

Curves (3)

来源生物 organism	Aquifex aeolicus
NCBI 分类编号 ncbi_taxonomy_id	63363
宿主生物 host_organism	Escherichia coli

描述 description	ADENOSINE-5'-DIPHOSPHATE
分子量 formula_weight	427.2 kDa
来源方法 src_method	syn
拷贝数 entity_count	14

fit	/app/data/saxs_computation/ny/1ny6/1ny6.fit
pddf	/app/data/pr_computation/ny/1ny6/1ny6.pr.out
profile	/app/data/saxs_computation/ny/1ny6/1ny6.dat