1p8j

CRYSTAL STRUCTURE OF THE PROPROTEIN CONVERTASE FURIN

Method: X-RAY DIFFRACTION

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1. 蛋白身份与相关结构 Protein Identity & Related Structures

Furin precursor

Mus musculus

当前结构中的状态

Assembly	物理组成	蛋白状态	分子拷贝数	共同组分	数据核对
1	其他组合	异源复合物	蛋白 8 其他聚合物 1	DECANOYL-ARG-VAL-LYS-ARG-CHLOROMETHYLKETONE INHIBITOR × 4 ;beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-[beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose ; × 1 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 CALCIUM ION × 8 SULFATE ION × 36 water × 8	与蛋白数一致
10	蛋白异源复合物	异源复合物	蛋白 2	DECANOYL-ARG-VAL-LYS-ARG-CHLOROMETHYLKETONE INHIBITOR × 1 CALCIUM ION × 2 SULFATE ION × 10 water × 2	与蛋白数一致
11	其他组合	异源复合物	蛋白 4 其他聚合物 2	DECANOYL-ARG-VAL-LYS-ARG-CHLOROMETHYLKETONE INHIBITOR × 2 ;beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-[beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose ; × 1 ;beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose ; × 1 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 CALCIUM ION × 4 SULFATE ION × 19 water × 4	与蛋白数一致
2	其他组合	异源复合物	蛋白 8 其他聚合物 1	DECANOYL-ARG-VAL-LYS-ARG-CHLOROMETHYLKETONE INHIBITOR × 4 ;beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose ; × 1 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 CALCIUM ION × 8 SULFATE ION × 34 water × 8	与蛋白数一致
3	蛋白异源复合物	异源复合物	蛋白 2	DECANOYL-ARG-VAL-LYS-ARG-CHLOROMETHYLKETONE INHIBITOR × 1 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 CALCIUM ION × 2 SULFATE ION × 10 water × 2	与蛋白数一致
4	蛋白异源复合物	异源复合物	蛋白 2	DECANOYL-ARG-VAL-LYS-ARG-CHLOROMETHYLKETONE INHIBITOR × 1 CALCIUM ION × 2 SULFATE ION × 7 water × 2	与蛋白数一致
5	其他组合	异源复合物	蛋白 2 其他聚合物 1	DECANOYL-ARG-VAL-LYS-ARG-CHLOROMETHYLKETONE INHIBITOR × 1 ;beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-[beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose ; × 1 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 CALCIUM ION × 2 SULFATE ION × 12 water × 2	与蛋白数一致
6	蛋白异源复合物	异源复合物	蛋白 2	DECANOYL-ARG-VAL-LYS-ARG-CHLOROMETHYLKETONE INHIBITOR × 1 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 CALCIUM ION × 2 SULFATE ION × 10 water × 2	与蛋白数一致
7	其他组合	异源复合物	蛋白 2 其他聚合物 1	DECANOYL-ARG-VAL-LYS-ARG-CHLOROMETHYLKETONE INHIBITOR × 1 ;beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose ; × 1 CALCIUM ION × 2 SULFATE ION × 7 water × 2	与蛋白数一致
8	蛋白异源复合物	异源复合物	蛋白 2	DECANOYL-ARG-VAL-LYS-ARG-CHLOROMETHYLKETONE INHIBITOR × 1 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 CALCIUM ION × 2 SULFATE ION × 7 water × 2	与蛋白数一致
9	蛋白异源复合物	异源复合物	蛋白 2	DECANOYL-ARG-VAL-LYS-ARG-CHLOROMETHYLKETONE INHIBITOR × 1 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 CALCIUM ION × 2 SULFATE ION × 7 water × 2	与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据

UniProt名称	FURI_MOUSE
Isoform	—
PDB实体	1
链与序列区间	作者链 A； PDB构建体 1–471； UniProt 108–578 作者链 B； PDB构建体 1–471； UniProt 108–578 作者链 C； PDB构建体 1–471； UniProt 108–578 作者链 D； PDB构建体 1–471； UniProt 108–578 作者链 E； PDB构建体 1–471； UniProt 108–578 作者链 F； PDB构建体 1–471； UniProt 108–578 作者链 G； PDB构建体 1–471； UniProt 108–578 作者链 H； PDB构建体 1–471； UniProt 108–578

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。

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2. 结构基本信息 2. Structure Basics

条目编号 entry_id	1p8j
沉积日期 deposition_date	2003-05-07
结构标题 title	CRYSTAL STRUCTURE OF THE PROPROTEIN CONVERTASE FURIN
关键词 keywords	PROHORMONE CONVERTASE, SPC1, PACE, P-DOMAIN, CHLOROMETHYLKETONE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX; HYDROLASE/HYDROLASE INHIBITOR
实验方法 method	X-RAY DIFFRACTION

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3. Official assembly/model 理论 SAXS Official SAXS Profiles

页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。

1p8j__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

下载该曲线 .dat

1p8j__assembly_1__model_1 | I(q)

100 个绘图点；横轴和纵轴均采用对数尺度。

1p8j__assembly_1__model_1 | P(r) · Pending

P(r) 将按相同 assembly/model 分别计算和展示。

Rg（Guinier）	39.34 Å
Rg（电子密度）	38.89 Å
总 Rg	39.25 Å
原子数	14858
残基数	1884
排除体积	258870 Å³
最大 q	0.500 Å⁻¹

Assembly	Model	结构单元	聚集说明	状态	CRYSOL	操作
1	1	`1p8j__assembly_1__model_1`	octameric （8）	成功	4.1.3-1-20251215 (887e7ef)	查看下载
2	1	`1p8j__assembly_2__model_1`	octameric （8）	成功	4.1.3-1-20251215 (887e7ef)	查看下载
3	1	`1p8j__assembly_3__model_1`	dimeric （2）	成功	4.1.3-1-20251215 (887e7ef)	查看下载
4	1	`1p8j__assembly_4__model_1`	dimeric （2）	成功	4.1.3-1-20251215 (887e7ef)	查看下载
5	1	`1p8j__assembly_5__model_1`	dimeric （2）	成功	4.1.3-1-20251215 (887e7ef)	查看下载
6	1	`1p8j__assembly_6__model_1`	dimeric （2）	成功	4.1.3-1-20251215 (887e7ef)	查看下载
7	1	`1p8j__assembly_7__model_1`	dimeric （2）	成功	4.1.3-1-20251215 (887e7ef)	查看下载
8	1	`1p8j__assembly_8__model_1`	dimeric （2）	成功	4.1.3-1-20251215 (887e7ef)	查看下载
9	1	`1p8j__assembly_9__model_1`	dimeric （2）	成功	4.1.3-1-20251215 (887e7ef)	查看下载
10	1	`1p8j__assembly_10__model_1`	dimeric （2）	成功	4.1.3-1-20251215 (887e7ef)	查看下载
11	1	`1p8j__assembly_11__model_1`	tetrameric （4）	成功	4.1.3-1-20251215 (887e7ef)	查看下载

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4. 晶体学与实验 4. Crystallography & Experiment

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5. 实体与聚合物信息 Entities & Polymers (8)

实体 1 Entity 1 polymer

描述 description	Furin precursor
分子量 formula_weight	51151.3 kDa
EC 编号 ec_number	3.4.21.75
来源方法 src_method	man
拷贝数 entity_count	8

聚合物 Polymer

聚合物类型 type	polypeptide(L)
链编号 strand_id	A,B,C,D,E,F,G,H
原子数 atom_count	31923

DVYQEPTDPKFPQQWYLSGVTQRDLNVKEAWAQGFTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNADDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIVEILVEPKDIGKRLEVRKAVTACLGEPNHITRLEHVQARLTLSYNRRGDLAIHLISPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPAGEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGL

来源 Source

来源生物 organism	Mus musculus
通用名 common_name	house mouse
NCBI 分类编号 ncbi_taxonomy_id	10090
宿主生物 host_organism	Cricetulus griseus

实体 2 Entity 2 polymer

描述 description	DECANOYL-ARG-VAL-LYS-ARG-CHLOROMETHYLKETONE INHIBITOR
分子量 formula_weight	749.5 kDa
来源方法 src_method	syn
拷贝数 entity_count	8

聚合物 Polymer

聚合物类型 type	polypeptide(L)
链编号 strand_id	J,K,L,M,N,P,Q,R

XRVKRX

实体 3 Entity 3 branched

描述 description	;beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-[beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose ;
分子量 formula_weight	1990.8 kDa
来源方法 src_method	man
拷贝数 entity_count	1

实体 4 Entity 4 branched

描述 description	;beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose ;
分子量 formula_weight	732.7 kDa
来源方法 src_method	man
拷贝数 entity_count	1

实体 5 Entity 5 non-polymer

描述 description	2-acetamido-2-deoxy-beta-D-glucopyranose
分子量 formula_weight	221.2 kDa
来源方法 src_method	man
拷贝数 entity_count	6

实体 6 Entity 6 non-polymer

描述 description	CALCIUM ION
分子量 formula_weight	40.1 kDa
来源方法 src_method	syn
拷贝数 entity_count	16

实体 7 Entity 7 non-polymer

描述 description	SULFATE ION
分子量 formula_weight	96.1 kDa
来源方法 src_method	syn
拷贝数 entity_count	70

实体 8 Entity 8 water

描述 description	water
分子量 formula_weight	18.0 kDa
来源方法 src_method	nat
拷贝数 entity_count	2305

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6. 折叠分类 (SCOP + CATH) 32 domains

SCOP 2.08 (16 domains)

结构域编号 domain_id	d1p8ja1
类 Class class	b — All beta proteins
折叠类型 Fold fold	b.18 — Galactose-binding domain-like
超家族 Superfamily superfamily	b.18.1 — Galactose-binding domain-like
家族 Family family	b.18.1.20 — Proprotein convertase P-domain

结构域编号 domain_id	d1p8ja2
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.41 — Subtilisin-like
超家族 Superfamily superfamily	c.41.1 — Subtilisin-like
家族 Family family	c.41.1.1 — Subtilases

结构域编号 domain_id	d1p8jb1
类 Class class	b — All beta proteins
折叠类型 Fold fold	b.18 — Galactose-binding domain-like
超家族 Superfamily superfamily	b.18.1 — Galactose-binding domain-like
家族 Family family	b.18.1.20 — Proprotein convertase P-domain

结构域编号 domain_id	d1p8jb2
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.41 — Subtilisin-like
超家族 Superfamily superfamily	c.41.1 — Subtilisin-like
家族 Family family	c.41.1.1 — Subtilases

结构域编号 domain_id	d1p8jc1
类 Class class	b — All beta proteins
折叠类型 Fold fold	b.18 — Galactose-binding domain-like
超家族 Superfamily superfamily	b.18.1 — Galactose-binding domain-like
家族 Family family	b.18.1.20 — Proprotein convertase P-domain

结构域编号 domain_id	d1p8jc2
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.41 — Subtilisin-like
超家族 Superfamily superfamily	c.41.1 — Subtilisin-like
家族 Family family	c.41.1.1 — Subtilases

结构域编号 domain_id	d1p8jd1
类 Class class	b — All beta proteins
折叠类型 Fold fold	b.18 — Galactose-binding domain-like
超家族 Superfamily superfamily	b.18.1 — Galactose-binding domain-like
家族 Family family	b.18.1.20 — Proprotein convertase P-domain

结构域编号 domain_id	d1p8jd2
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.41 — Subtilisin-like
超家族 Superfamily superfamily	c.41.1 — Subtilisin-like
家族 Family family	c.41.1.1 — Subtilases

结构域编号 domain_id	d1p8je1
类 Class class	b — All beta proteins
折叠类型 Fold fold	b.18 — Galactose-binding domain-like
超家族 Superfamily superfamily	b.18.1 — Galactose-binding domain-like
家族 Family family	b.18.1.20 — Proprotein convertase P-domain

结构域编号 domain_id	d1p8je2
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.41 — Subtilisin-like
超家族 Superfamily superfamily	c.41.1 — Subtilisin-like
家族 Family family	c.41.1.1 — Subtilases

结构域编号 domain_id	d1p8jf1
类 Class class	b — All beta proteins
折叠类型 Fold fold	b.18 — Galactose-binding domain-like
超家族 Superfamily superfamily	b.18.1 — Galactose-binding domain-like
家族 Family family	b.18.1.20 — Proprotein convertase P-domain

结构域编号 domain_id	d1p8jf2
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.41 — Subtilisin-like
超家族 Superfamily superfamily	c.41.1 — Subtilisin-like
家族 Family family	c.41.1.1 — Subtilases

结构域编号 domain_id	d1p8jg1
类 Class class	b — All beta proteins
折叠类型 Fold fold	b.18 — Galactose-binding domain-like
超家族 Superfamily superfamily	b.18.1 — Galactose-binding domain-like
家族 Family family	b.18.1.20 — Proprotein convertase P-domain

结构域编号 domain_id	d1p8jg2
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.41 — Subtilisin-like
超家族 Superfamily superfamily	c.41.1 — Subtilisin-like
家族 Family family	c.41.1.1 — Subtilases

结构域编号 domain_id	d1p8jh1
类 Class class	b — All beta proteins
折叠类型 Fold fold	b.18 — Galactose-binding domain-like
超家族 Superfamily superfamily	b.18.1 — Galactose-binding domain-like
家族 Family family	b.18.1.20 — Proprotein convertase P-domain

结构域编号 domain_id	d1p8jh2
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.41 — Subtilisin-like
超家族 Superfamily superfamily	c.41.1 — Subtilisin-like
家族 Family family	c.41.1.1 — Subtilases

CATH v4.4 (16 domains)

结构域编号 domain_id	1p8jA01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	200 — Peptidase S8/S53 domain

结构域编号 domain_id	1p8jA02
类 Class class	2 — Mainly Beta
架构 Architecture architecture	60 — Sandwich
拓扑 Topology topology	120 — Jelly Rolls
同源超家族 H-superfamily homologous superfamily	260 — Galactose-binding domain-like

结构域编号 domain_id	1p8jB01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	200 — Peptidase S8/S53 domain

结构域编号 domain_id	1p8jB02
类 Class class	2 — Mainly Beta
架构 Architecture architecture	60 — Sandwich
拓扑 Topology topology	120 — Jelly Rolls
同源超家族 H-superfamily homologous superfamily	260 — Galactose-binding domain-like

结构域编号 domain_id	1p8jC01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	200 — Peptidase S8/S53 domain

结构域编号 domain_id	1p8jC02
类 Class class	2 — Mainly Beta
架构 Architecture architecture	60 — Sandwich
拓扑 Topology topology	120 — Jelly Rolls
同源超家族 H-superfamily homologous superfamily	260 — Galactose-binding domain-like

结构域编号 domain_id	1p8jD01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	200 — Peptidase S8/S53 domain

结构域编号 domain_id	1p8jD02
类 Class class	2 — Mainly Beta
架构 Architecture architecture	60 — Sandwich
拓扑 Topology topology	120 — Jelly Rolls
同源超家族 H-superfamily homologous superfamily	260 — Galactose-binding domain-like

结构域编号 domain_id	1p8jE01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	200 — Peptidase S8/S53 domain

结构域编号 domain_id	1p8jE02
类 Class class	2 — Mainly Beta
架构 Architecture architecture	60 — Sandwich
拓扑 Topology topology	120 — Jelly Rolls
同源超家族 H-superfamily homologous superfamily	260 — Galactose-binding domain-like

结构域编号 domain_id	1p8jF01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	200 — Peptidase S8/S53 domain

结构域编号 domain_id	1p8jF02
类 Class class	2 — Mainly Beta
架构 Architecture architecture	60 — Sandwich
拓扑 Topology topology	120 — Jelly Rolls
同源超家族 H-superfamily homologous superfamily	260 — Galactose-binding domain-like

结构域编号 domain_id	1p8jG01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	200 — Peptidase S8/S53 domain

结构域编号 domain_id	1p8jG02
类 Class class	2 — Mainly Beta
架构 Architecture architecture	60 — Sandwich
拓扑 Topology topology	120 — Jelly Rolls
同源超家族 H-superfamily homologous superfamily	260 — Galactose-binding domain-like

结构域编号 domain_id	1p8jH01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	200 — Peptidase S8/S53 domain

结构域编号 domain_id	1p8jH02
类 Class class	2 — Mainly Beta
架构 Architecture architecture	60 — Sandwich
拓扑 Topology topology	120 — Jelly Rolls
同源超家族 H-superfamily homologous superfamily	260 — Galactose-binding domain-like

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晶胞边长 a length_a	93.305 Å
晶胞边长 b length_b	135.392 Å
晶胞边长 c length_c	137.806 Å
晶胞夹角 α angle_alpha	103.56 °
晶胞夹角 β angle_beta	98.98 °
晶胞夹角 γ angle_gamma	107.09 °
晶胞分子数 Z z_pdb	8

空间群 space_group	P 1
空间群编号 int_tables_number	1
晶系 crystal_system	—

分辨率 resolution	2.600 Å
最低分辨率 resolution_low	18.820 Å
R 因子 r_factor	0.1880
R_work r_work	0.1880
R_free r_free	0.2190

CRYSTAL STRUCTURE OF THE PROPROTEIN CONVERTASE FURIN

1. 蛋白身份与相关结构 Protein Identity & Related Structures

Furin precursor

当前结构中的状态

数据库中的同蛋白其他状态

2. 结构基本信息 2. Structure Basics

3. Official assembly/model 理论 SAXS Official SAXS Profiles

1p8j__assembly_1__model_1

1p8j__assembly_1__model_1 | I(q)

1p8j__assembly_1__model_1 | P(r) · Pending

4. 晶体学与实验 4. Crystallography & Experiment

晶胞参数 Unit Cell

对称性 Symmetry

精修参数 Refinement

衍射实验 Diffraction

5. 实体与聚合物信息 Entities & Polymers (8)

实体 1 Entity 1 polymer

聚合物 Polymer

来源 Source

实体 2 Entity 2 polymer

聚合物 Polymer

实体 3 Entity 3 branched

实体 4 Entity 4 branched

实体 5 Entity 5 non-polymer

实体 6 Entity 6 non-polymer

实体 7 Entity 7 non-polymer

实体 8 Entity 8 water

6. 折叠分类 (SCOP + CATH) 32 domains

SCOP 2.08 (16 domains)

CATH v4.4 (16 domains)

7. 引用文献 (1)

CRYSTAL STRUCTURE OF THE PROPROTEIN CONVERTASE FURIN

1. 蛋白身份与相关结构 Protein Identity & Related Structures

Furin precursor

当前结构中的状态

数据库中的同蛋白其他状态

单体

同源二聚体

同源四聚体

其他同源多聚体

异源或核酸复合物

2. 结构基本信息 2. Structure Basics

3. Official assembly/model 理论 SAXS Official SAXS Profiles

1p8j__assembly_1__model_1

1p8j__assembly_1__model_1 | I(q)

1p8j__assembly_1__model_1 | P(r) · Pending

4. 晶体学与实验 4. Crystallography & Experiment

晶胞参数 Unit Cell

对称性 Symmetry

精修参数 Refinement

衍射实验 Diffraction

5. 实体与聚合物信息 Entities & Polymers (8)

实体 1 Entity 1 polymer

聚合物 Polymer

来源 Source

实体 2 Entity 2 polymer

聚合物 Polymer

实体 3 Entity 3 branched

实体 4 Entity 4 branched

实体 5 Entity 5 non-polymer

实体 6 Entity 6 non-polymer

实体 7 Entity 7 non-polymer

实体 8 Entity 8 water

6. 折叠分类 (SCOP + CATH) 32 domains

SCOP 2.08 (16 domains)

CATH v4.4 (16 domains)

7. 引用文献 (1)