1q4g
2.0 Angstrom Crystal Structure of Ovine Prostaglandin H2 Synthase-1, in complex with alpha-methyl-4-biphenylacetic acid
1. Protein Identity and Related Structures Protein Identity & Related Structures
No usable UniProt protein identity is available for this entry.
The relationship tables retain this entry's assembly and composition data, but cross-PDB links for the same protein cannot be established reliably without a unified protein identity.
Assembly Composition of the Current Entry
| Assembly | Physical composition | Protein state | 蛋白 / DNA / RNA / 其他Polymer | Data consistency |
|---|---|---|---|---|
| 1 | Other combination | Homooligomer | 2 / 0 / 0 / 6 | Consistent with protein count |
The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.
2. Structure Basics 2. Structure Basics
| Entry ID entry_id | 1q4g |
| Deposition date deposition_date | 2003-08-03 |
| Structure title title | 2.0 Angstrom Crystal Structure of Ovine Prostaglandin H2 Synthase-1, in complex with alpha-methyl-4-biphenylacetic acid |
| Keywords keywords | ;cyclooxygenase, non-steroidal anti-inflammatory drug, peroxidase, prostaglandin synthase, EGF-like domain, membrane binding domain, OXIDOREDUCTASE ;; OXIDOREDUCTASE |
| Experimental Method method | X-RAY DIFFRACTION |
3. Official assembly/model SAXS Official SAXS Profiles
This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.
1q4g__assembly_1__model_1
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
1q4g__assembly_1__model_1 | I(q)
1q4g__assembly_1__model_1 | P(r) · Pending
| Rg（Guinier） | 32.57 Å |
| Rg (electron density) | 31.67 Å |
| Total Rg | 32.47 Å |
| Atom count | 9572 |
| Residues | 1106 |
| Excluded volume | 171960 ų |
| Maximum q | 0.500 Å⁻¹ |
4. Crystallography and Experiment 4. Crystallography & Experiment
5. Entities and Polymers Entities & Polymers (10)
6. Fold Classification (SCOP + CATH) 8 domains
SCOP 2.08 (4 domains)
| Domain ID domain_id | d1q4ga1 |
| Class class | a — All alpha proteins |
| Fold Fold fold | a.93 — Heme-dependent peroxidases |
| Superfamily Superfamily superfamily | a.93.1 — Heme-dependent peroxidases |
| Family Family family | a.93.1.2 — Myeloperoxidase-like |
| Domain ID domain_id | d1q4ga2 |
| Class class | g — Small proteins |
| Fold Fold fold | g.3 — Knottins (small inhibitors, toxins, lectins) |
| Superfamily Superfamily superfamily | g.3.11 — EGF/Laminin |
| Family Family family | g.3.11.1 — EGF-type module |
| Domain ID domain_id | d1q4gb1 |
| Class class | a — All alpha proteins |
| Fold Fold fold | a.93 — Heme-dependent peroxidases |
| Superfamily Superfamily superfamily | a.93.1 — Heme-dependent peroxidases |
| Family Family family | a.93.1.2 — Myeloperoxidase-like |
| Domain ID domain_id | d1q4gb2 |
| Class class | g — Small proteins |
| Fold Fold fold | g.3 — Knottins (small inhibitors, toxins, lectins) |
| Superfamily Superfamily superfamily | g.3.11 — EGF/Laminin |
| Family Family family | g.3.11.1 — EGF-type module |
CATH v4.4 (4 domains)
| Domain ID domain_id | 1q4gA01 |
| Class class | 2 — Mainly Beta |
| Architecture architecture | 10 — Ribbon |
| Topology topology | 25 — Laminin |
| Homologous superfamily homologous superfamily | 10 — Laminin |
| Domain ID domain_id | 1q4gA02 |
| Class class | 1 — Mainly Alpha |
| Architecture architecture | 10 — Orthogonal Bundle |
| Topology topology | 640 — Myeloperoxidase, subunit C |
| Homologous superfamily homologous superfamily | 10 — Haem peroxidase domain superfamily, animal type |
| Domain ID domain_id | 1q4gB01 |
| Class class | 2 — Mainly Beta |
| Architecture architecture | 10 — Ribbon |
| Topology topology | 25 — Laminin |
| Homologous superfamily homologous superfamily | 10 — Laminin |
| Domain ID domain_id | 1q4gB02 |
| Class class | 1 — Mainly Alpha |
| Architecture architecture | 10 — Orthogonal Bundle |
| Topology topology | 640 — Myeloperoxidase, subunit C |
| Homologous superfamily homologous superfamily | 10 — Haem peroxidase domain superfamily, animal type |