1r0d

HIP1R THATCH DOMAIN CORE

Method: X-RAY DIFFRACTION

▼

1. Protein Identity and Related Structures Protein Identity & Related Structures

Huntingtin Interacting Protein 12

Homo sapiens

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein monomer	Monomer	Protein 1	water × 1	Consistent with protein count
2	Protein monomer	Monomer	Protein 1	water × 1	Consistent with protein count
3	Protein monomer	Monomer	Protein 1	water × 1	Consistent with protein count
4	Protein monomer	Monomer	Protein 1	water × 1	Consistent with protein count
5	Protein monomer	Monomer	Protein 1	water × 1	Consistent with protein count
6	Protein monomer	Monomer	Protein 1	water × 1	Consistent with protein count
7	Protein monomer	Monomer	Protein 1	water × 1	Consistent with protein count
8	Protein monomer	Monomer	Protein 1	water × 1	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	HIP1R_HUMAN
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain A； PDBConstruct 6–206； UniProt 771–971 Author chain B； PDBConstruct 6–206； UniProt 771–971 Author chain D； PDBConstruct 6–206； UniProt 771–971 Author chain E； PDBConstruct 6–206； UniProt 771–971 Author chain F； PDBConstruct 6–206； UniProt 771–971 Author chain G； PDBConstruct 6–206； UniProt 771–971 Author chain H； PDBConstruct 6–206； UniProt 771–971 Author chain I； PDBConstruct 6–206； UniProt 771–971

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

▼

2. Structure Basics 2. Structure Basics

Entry ID entry_id	1r0d
Deposition date deposition_date	2003-09-19
Structure title title	HIP1R THATCH DOMAIN CORE
Keywords keywords	;Endocytosis, Actin-binding, Structural Genomics, PSI, Protein Structure Initiative, Midwest Center for Structural Genomics, MCSG, STRUCTURAL PROTEIN ;; STRUCTURAL PROTEIN
Experimental Method method	X-RAY DIFFRACTION

▼

3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

1r0d__assembly_6__model_1

Assembly 6 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

1r0d__assembly_6__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

1r0d__assembly_6__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	19.53 Å
Rg (electron density)	18.89 Å
Total Rg	19.41 Å
Atom count	1440
Residues	186
Excluded volume	25430 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`1r0d__assembly_1__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
2	1	`1r0d__assembly_2__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
3	1	`1r0d__assembly_3__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
4	1	`1r0d__assembly_4__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
5	1	`1r0d__assembly_5__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
6	1	`1r0d__assembly_6__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
7	1	`1r0d__assembly_7__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
8	1	`1r0d__assembly_8__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download

▶

4. Crystallography and Experiment 4. Crystallography & Experiment

▶

5. Entities and Polymers Entities & Polymers (2)

▼

6. Fold Classification (SCOP + CATH) 16 domains

SCOP 2.08 (8 domains)

Domain ID domain_id	d1r0da_
Class class	a — All alpha proteins
Fold Fold fold	a.216 — I/LWEQ domain
Superfamily Superfamily superfamily	a.216.1 — I/LWEQ domain
Family Family family	a.216.1.1 — I/LWEQ domain

Domain ID domain_id	d1r0db_
Class class	a — All alpha proteins
Fold Fold fold	a.216 — I/LWEQ domain
Superfamily Superfamily superfamily	a.216.1 — I/LWEQ domain
Family Family family	a.216.1.1 — I/LWEQ domain

Domain ID domain_id	d1r0dd_
Class class	a — All alpha proteins
Fold Fold fold	a.216 — I/LWEQ domain
Superfamily Superfamily superfamily	a.216.1 — I/LWEQ domain
Family Family family	a.216.1.1 — I/LWEQ domain

Domain ID domain_id	d1r0de_
Class class	a — All alpha proteins
Fold Fold fold	a.216 — I/LWEQ domain
Superfamily Superfamily superfamily	a.216.1 — I/LWEQ domain
Family Family family	a.216.1.1 — I/LWEQ domain

Domain ID domain_id	d1r0df_
Class class	a — All alpha proteins
Fold Fold fold	a.216 — I/LWEQ domain
Superfamily Superfamily superfamily	a.216.1 — I/LWEQ domain
Family Family family	a.216.1.1 — I/LWEQ domain

Domain ID domain_id	d1r0dg_
Class class	a — All alpha proteins
Fold Fold fold	a.216 — I/LWEQ domain
Superfamily Superfamily superfamily	a.216.1 — I/LWEQ domain
Family Family family	a.216.1.1 — I/LWEQ domain

Domain ID domain_id	d1r0dh_
Class class	a — All alpha proteins
Fold Fold fold	a.216 — I/LWEQ domain
Superfamily Superfamily superfamily	a.216.1 — I/LWEQ domain
Family Family family	a.216.1.1 — I/LWEQ domain

Domain ID domain_id	d1r0di_
Class class	a — All alpha proteins
Fold Fold fold	a.216 — I/LWEQ domain
Superfamily Superfamily superfamily	a.216.1 — I/LWEQ domain
Family Family family	a.216.1.1 — I/LWEQ domain

CATH v4.4 (8 domains)

Domain ID domain_id	1r0dA00
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	1410 — I/LWEQ domain
Homologous superfamily homologous superfamily	10 — I/LWEQ domain

Domain ID domain_id	1r0dB00
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	1410 — I/LWEQ domain
Homologous superfamily homologous superfamily	10 — I/LWEQ domain

Domain ID domain_id	1r0dD00
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	1410 — I/LWEQ domain
Homologous superfamily homologous superfamily	10 — I/LWEQ domain

Domain ID domain_id	1r0dE00
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	1410 — I/LWEQ domain
Homologous superfamily homologous superfamily	10 — I/LWEQ domain

Domain ID domain_id	1r0dF00
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	1410 — I/LWEQ domain
Homologous superfamily homologous superfamily	10 — I/LWEQ domain

Domain ID domain_id	1r0dG00
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	1410 — I/LWEQ domain
Homologous superfamily homologous superfamily	10 — I/LWEQ domain

Domain ID domain_id	1r0dH00
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	1410 — I/LWEQ domain
Homologous superfamily homologous superfamily	10 — I/LWEQ domain

Domain ID domain_id	1r0dI00
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	1410 — I/LWEQ domain
Homologous superfamily homologous superfamily	10 — I/LWEQ domain

▶

Unit-cell length a length_a	148.200 Å
Unit-cell length b length_b	165.900 Å
Unit-cell length c length_c	109.800 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	132.40 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	32

Space group space_group	C 1 2 1
Space-group number int_tables_number	5
Crystal system crystal_system	—

Resolution resolution	1.900 Å
Low-resolution limit resolution_low	19.880 Å
R factor r_factor	0.2241
R_work r_work	0.2240
R_free r_free	0.2690

Description description	Huntingtin Interacting Protein 12
Molecular weight formula_weight	22609.6 kDa
Source method src_method	man
Copy count entity_count	8

Polymer type type	polypeptide(L)
Chain IDs strand_id	A,B,D,E,F,G,H,I
Atom count atom_count	12737

HIP1R THATCH DOMAIN CORE

1. Protein Identity and Related Structures Protein Identity & Related Structures

Huntingtin Interacting Protein 12

State in the Current Structure

Other States of the Same Protein in the Database

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

1r0d__assembly_6__model_1

1r0d__assembly_6__model_1 | I(q)

1r0d__assembly_6__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

5. Entities and Polymers Entities & Polymers (2)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 water

6. Fold Classification (SCOP + CATH) 16 domains

SCOP 2.08 (8 domains)

CATH v4.4 (8 domains)

7. Citations (1)

Source organism organism	Homo sapiens
Common name common_name	human
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	Escherichia coli BL21(DE3)

Description description	water
Molecular weight formula_weight	18.0 kDa
Source method src_method	nat
Copy count entity_count	1149

HIP1R THATCH DOMAIN CORE

1. Protein Identity and Related Structures Protein Identity & Related Structures

Huntingtin Interacting Protein 12

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

1r0d__assembly_6__model_1

1r0d__assembly_6__model_1 | I(q)

1r0d__assembly_6__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

5. Entities and Polymers Entities & Polymers (2)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 water

6. Fold Classification (SCOP + CATH) 16 domains

SCOP 2.08 (8 domains)

CATH v4.4 (8 domains)

7. Citations (1)