hypothetical protein PF0537
Pyrococcus furiosus
当前结构中的状态
| Assembly | 物理组成 | 蛋白状态 | 分子拷贝数 | 共同组分 | 数据核对 |
|---|---|---|---|---|---|
| 1 | 蛋白单体 | 单体 | 蛋白 1 | water × 1 | 与蛋白数一致 |
数据库中的同蛋白其他状态
查看构建体与数据证据
| UniProt名称 | Q8U3D2_PYRFU |
| Isoform | — |
| PDB实体 | 1 |
| 链与序列区间 | 作者链 A； PDB构建体 2–771； UniProt 1–770 |
1u04
Crystal structure of full length Argonaute from Pyrococcus furiosus
1. 蛋白身份与相关结构 Protein Identity & Related Structures
页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。
2. 结构基本信息 2. Structure Basics
| 条目编号 entry_id | 1u04 |
| 沉积日期 deposition_date | 2004-07-12 |
| 结构标题 title | Crystal structure of full length Argonaute from Pyrococcus furiosus |
| 关键词 keywords | RNAi, Silencing, Argonaute, PIWI, PAZ, RISC, Slicer, RNase H, HYDROLASE-GENE REGULATION COMPLEX; HYDROLASE/GENE REGULATION |
| 实验方法 method | X-RAY DIFFRACTION |
3. Official assembly/model 理论 SAXS Official SAXS Profiles
页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。
1u04__assembly_1__model_1
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
1u04__assembly_1__model_1 | I(q)
1u04__assembly_1__model_1 | P(r) · Pending
| Rg（Guinier） | 29.21 Å |
| Rg（电子密度） | 28.18 Å |
| 总 Rg | 28.89 Å |
| 原子数 | 5920 |
| 残基数 | 695 |
| 排除体积 | 107570 ų |
| 最大 q | 0.500 Å⁻¹ |
4. 晶体学与实验 4. Crystallography & Experiment
5. 实体与聚合物信息 Entities & Polymers (2)
6. 折叠分类 (SCOP + CATH) 7 domains
SCOP 2.08 (4 domains)
| 结构域编号 domain_id | d1u04a1 |
| 类 Class class | b — All beta proteins |
| 折叠类型 Fold fold | b.34 — SH3-like barrel |
| 超家族 Superfamily superfamily | b.34.14 — PAZ domain |
| 家族 Family family | b.34.14.1 — PAZ domain |
| 结构域编号 domain_id | d1u04a3 |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.44 — Phosphotyrosine protein phosphatases I-like |
| 超家族 Superfamily superfamily | c.44.3 — PIWI domain N-terminal-like |
| 家族 Family family | c.44.3.1 — PIWI domain N-terminal |
| 结构域编号 domain_id | d1u04a4 |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.55 — Ribonuclease H-like motif |
| 超家族 Superfamily superfamily | c.55.3 — Ribonuclease H-like |
| 家族 Family family | c.55.3.15 — PIWI domain C-terminal |
| 结构域编号 domain_id | d1u04a5 |
| 类 Class class | l — Artifacts |
| 折叠类型 Fold fold | l.1 — Tags |
| 超家族 Superfamily superfamily | l.1.1 — Tags |
| 家族 Family family | l.1.1.1 — Tags |
CATH v4.4 (3 domains)
| 结构域编号 domain_id | 1u04A02 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 90 — Alpha-Beta Complex |
| 拓扑 Topology topology | 70 — Cathepsin B; Chain A |
| 同源超家族 H-superfamily homologous superfamily | 180 — |
| 结构域编号 domain_id | 1u04A03 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 50 — Rossmann fold |
| 同源超家族 H-superfamily homologous superfamily | 2300 — Response regulator |
| 结构域编号 domain_id | 1u04A04 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 420 — Nucleotidyltransferase; domain 5 |
| 同源超家族 H-superfamily homologous superfamily | 10 — Ribonuclease H-like superfamily/Ribonuclease H |