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1wja

SOLUTION STRUCTURE OF THE N-TERMINAL ZN BINDING DOMAIN OF HIV-1 INTEGRASE (D FORM), NMR, REGULARIZED MEAN STRUCTURE

Method: SOLUTION NMR
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1. Protein Identity and Related Structures Protein Identity & Related Structures

HIV-1 INTEGRASE

Human immunodeficiency virus 1

UniProt P35963

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein homooligomer Homooligomer Protein 2 ZINC ION × 2 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1mfs 2jo0

2 assemblies

Homodimer
1k6c 1k6p 1k6t 1k6v 1t7i 1t7j 1wja 1wjc

8 assemblies

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
2l6e

1 assemblies

View Construct and Data Evidence
UniProt name POL_HV1Y2
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–47； UniProt 716–762 Author chain B； PDBConstruct 1–47； UniProt 716–762

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id1wja
Deposition date deposition_date1997-05-13
Structure title titleSOLUTION STRUCTURE OF THE N-TERMINAL ZN BINDING DOMAIN OF HIV-1 INTEGRASE (D FORM), NMR, REGULARIZED MEAN STRUCTURE
Keywords keywordsZN-BINDING PROTEIN, AIDS, POLYPROTEIN, HYDROLASE, ASPARTYL PROTEASE, ENDONUCLEASE; ZN-BINDING PROTEIN
Experimental Method methodSOLUTION NMR
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

1wja__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

1wja__assembly_1__model_1 | I(q)

10-2 10-1 105 106 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

1wja__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）15.17 Å
Rg (electron density)13.90 Å
Total Rg15.12 Å
Atom count1462
Residues94
Excluded volume13210 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 1wja__assembly_1__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (2)

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6. Fold Classification (SCOP + CATH) 4 domains

SCOP 2.08 (2 domains)

Domain ID domain_idd1wjaa_
Class classa — All alpha proteins
Fold Fold folda.4 — DNA/RNA-binding 3-helical bundle
Superfamily Superfamily superfamilya.4.10 — Retroviral integrase, N-terminal Zn binding domain
Family Family familya.4.10.1 — HIV/SIV integrase, N-terminal Zn binding domain
Domain ID domain_idd1wjab_
Class classa — All alpha proteins
Fold Fold folda.4 — DNA/RNA-binding 3-helical bundle
Superfamily Superfamily superfamilya.4.10 — Retroviral integrase, N-terminal Zn binding domain
Family Family familya.4.10.1 — HIV/SIV integrase, N-terminal Zn binding domain

CATH v4.4 (2 domains)

Domain ID domain_id1wjaA00
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology10 — Arc Repressor Mutant, subunit A
Homologous superfamily homologous superfamily200 — Integrase, N-terminal zinc-binding domain
Domain ID domain_id1wjaB00
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology10 — Arc Repressor Mutant, subunit A
Homologous superfamily homologous superfamily200 — Integrase, N-terminal zinc-binding domain
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7. Citations (1)