1wkb

Crystal Structure of Leucyl-tRNA Synthetase from the Archaeon Pyrococcus horikoshii Reveals a Novel Editing Domain Orientation

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Leucyl-tRNA synthetase

Pyrococcus horikoshii

UniProt O58698

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein monomer Monomer Protein 1 SULFATE ION × 8 water × 1 Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SYL_PYRHO
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A; PDBConstruct 1–810; UniProt 1–810

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id1wkb
Deposition date deposition_date2004-05-30
Structure title titleCrystal Structure of Leucyl-tRNA Synthetase from the Archaeon Pyrococcus horikoshii Reveals a Novel Editing Domain Orientation
Keywords keywords;leucyl-trna synthetase, leucine, aminoacyl-trna, editing, amino acid, aminoacylation, pyrococcus horikoshii, trnaleu, Structural Genomics, RIKEN Structural Genomics/Proteomics Initiative, RSGI, Ligase ;; LIGASE
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

1wkb__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

1wkb__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

1wkb__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)32.88 Å
Rg (electron density)32.53 Å
Total Rg33.05 Å
Atom count6650
Residues791
Excluded volume119080 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 1wkb__assembly_1__model_1 monomeric (1) Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

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6. Fold Classification (SCOP + CATH) 3 domains

CATH v4.4 (3 domains)

Domain ID domain_id1wkbA01
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily620 — HUPs
Domain ID domain_id1wkbA02
Class class3 — Alpha Beta
Architecture architecture90 — Alpha-Beta Complex
Topology topology740 — Isoleucyl-tRNA Synthetase; domain 2
Homologous superfamily homologous superfamily10 — Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain
Domain ID domain_id1wkbA03
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology730 — Isoleucyl-tRNA Synthetase; Domain 1
Homologous superfamily homologous superfamily10 — Isoleucyl-tRNA Synthetase; Domain 1
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7. Citations (1)