1xez

Crystal Structure Of The Vibrio Cholerae Cytolysin (HlyA) Pro-Toxin With Octylglucoside Bound

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

hemolysin

Vibrio cholerae

UniProt P09545

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein monomer Monomer Protein 1 octyl beta-D-glucopyranoside × 1 water × 1 Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name HLYA_VIBCH
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A; PDBConstruct 6–721; UniProt 26–741

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id1xez
Deposition date deposition_date2004-09-13
Structure title titleCrystal Structure Of The Vibrio Cholerae Cytolysin (HlyA) Pro-Toxin With Octylglucoside Bound
Keywords keywordsPore-forming toxin, hemolysin, cytolysin, pro-toxin, water-soluble monomer, beta-prism, beta-trefoil, toxin; TOXIN
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

1xez__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

1xez__assembly_1__model_1 | I(q)

10-2 10-1 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

1xez__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)32.00 Å
Rg (electron density)31.66 Å
Total Rg31.84 Å
Atom count5085
Residues663
Excluded volume88836 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 1xez__assembly_1__model_1 monomeric (1) Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

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6. Fold Classification (SCOP + CATH) 4 domains

CATH v4.4 (4 domains)

Domain ID domain_id1xezA01
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology110 — Translation Initiation Factor IF3
Homologous superfamily homologous superfamily130 — Hemolytic toxin, N-terminal domain
Domain ID domain_id1xezA02
Class class2 — Mainly Beta
Architecture architecture70 — Distorted Sandwich
Topology topology240 — Leukocidin-like
Homologous superfamily homologous superfamily20 — Leukocidin/Hemolysin toxin, cytolysin domain
Domain ID domain_id1xezA03
Class class6 — Special
Architecture architecture20 — Other non-globular
Topology topology40 — Porin MspA ribbon fold
Homologous superfamily homologous superfamily20 — Leukocidin/Hemolysin toxin, pre-stem domain
Domain ID domain_id1xezA04
Class class2 — Mainly Beta
Architecture architecture100 — Aligned Prism
Topology topology10 — Vitelline Membrane Outer Layer Protein I, subunit A
Homologous superfamily homologous superfamily30 — Jacalin-like lectin domain
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7. Citations (1)