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1y4o

Solution structure of a mouse cytoplasmic Roadblock/LC7 dynein light chain

Method: SOLUTION NMR
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Dynein light chain 2A, cytoplasmic

Mus musculus

UniProt P62627

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein homooligomer Homooligomer Protein 2 No other associated polymer Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer
1y4o

1 assemblies

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex

None

View Construct and Data Evidence
UniProt name DLC2A_MOUSE
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 10–104； UniProt 2–96 Author chain B； PDBConstruct 10–104； UniProt 2–96

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id1y4o
Deposition date deposition_date2004-12-01
Structure title titleSolution structure of a mouse cytoplasmic Roadblock/LC7 dynein light chain
Keywords keywords;Structural Genomics, Protein Structure Initiative, PSI, Center for Eukaryotic Structural Genomics, CESG, Dynein Light Chain, CONTRACTILE PROTEIN ;; CONTRACTILE PROTEIN
Experimental Method methodSOLUTION NMR
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

1y4o__assembly_1__model_11

Assembly 1 · Model 11 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

1y4o__assembly_1__model_11 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

1y4o__assembly_1__model_11 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）19.36 Å
Rg (electron density)17.99 Å
Total Rg18.84 Å
Atom count3386
Residues208
Excluded volume29853 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 1y4o__assembly_1__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
1 2 1y4o__assembly_1__model_2 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
1 3 1y4o__assembly_1__model_3 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
1 4 1y4o__assembly_1__model_4 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
1 5 1y4o__assembly_1__model_5 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
1 6 1y4o__assembly_1__model_6 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
1 7 1y4o__assembly_1__model_7 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
1 8 1y4o__assembly_1__model_8 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
1 9 1y4o__assembly_1__model_9 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
1 10 1y4o__assembly_1__model_10 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
1 11 1y4o__assembly_1__model_11 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
1 12 1y4o__assembly_1__model_12 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
1 13 1y4o__assembly_1__model_13 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
1 14 1y4o__assembly_1__model_14 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
1 15 1y4o__assembly_1__model_15 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
1 16 1y4o__assembly_1__model_16 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
1 17 1y4o__assembly_1__model_17 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
1 18 1y4o__assembly_1__model_18 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
1 19 1y4o__assembly_1__model_19 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
1 20 1y4o__assembly_1__model_20 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (1)

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6. Fold Classification (SCOP + CATH) 6 domains

SCOP 2.08 (4 domains)

Domain ID domain_idd1y4oa1
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.110 — Profilin-like
Superfamily Superfamily superfamilyd.110.7 — Roadblock/LC7 domain
Family Family familyd.110.7.1 — Roadblock/LC7 domain
Domain ID domain_idd1y4oa2
Class classl — Artifacts
Fold Fold foldl.1 — Tags
Superfamily Superfamily superfamilyl.1.1 — Tags
Family Family familyl.1.1.1 — Tags
Domain ID domain_idd1y4ob2
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.110 — Profilin-like
Superfamily Superfamily superfamilyd.110.7 — Roadblock/LC7 domain
Family Family familyd.110.7.1 — Roadblock/LC7 domain
Domain ID domain_idd1y4ob3
Class classl — Artifacts
Fold Fold foldl.1 — Tags
Superfamily Superfamily superfamilyl.1.1 — Tags
Family Family familyl.1.1.1 — Tags

CATH v4.4 (2 domains)

Domain ID domain_id1y4oA00
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology450 — Beta-Lactamase
Homologous superfamily homologous superfamily30 — Dynein light chain 2a, cytoplasmic
Domain ID domain_id1y4oB00
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology450 — Beta-Lactamase
Homologous superfamily homologous superfamily30 — Dynein light chain 2a, cytoplasmic
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7. Citations (1)