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1z7z

Cryo-em structure of human coxsackievirus A21 complexed with five domain icam-1kilifi

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Intercellular adhesion molecule-1

OrganismNot specified

UniProt P05362

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 360 human coxsackievirus A21 × 60 human coxsackievirus A21 × 60 human coxsackievirus A21 × 60 human coxsackievirus A21 × 60 human coxsackievirus A21 × 60 2-acetamido-2-deoxy-beta-D-glucopyranose × 480 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 6 human coxsackievirus A21 × 1 human coxsackievirus A21 × 1 human coxsackievirus A21 × 1 human coxsackievirus A21 × 1 human coxsackievirus A21 × 1 2-acetamido-2-deoxy-beta-D-glucopyranose × 8 Consistent with protein count
3 Protein heterocomplex Heteromer Protein 30 human coxsackievirus A21 × 5 human coxsackievirus A21 × 5 human coxsackievirus A21 × 5 human coxsackievirus A21 × 5 human coxsackievirus A21 × 5 2-acetamido-2-deoxy-beta-D-glucopyranose × 40 Consistent with protein count
4 Protein heterocomplex Heteromer Protein 36 human coxsackievirus A21 × 6 human coxsackievirus A21 × 6 human coxsackievirus A21 × 6 human coxsackievirus A21 × 6 human coxsackievirus A21 × 6 2-acetamido-2-deoxy-beta-D-glucopyranose × 48 Consistent with protein count
5 Protein heterocomplex Heteromer Protein 6 human coxsackievirus A21 × 1 human coxsackievirus A21 × 1 human coxsackievirus A21 × 1 human coxsackievirus A21 × 1 human coxsackievirus A21 × 1 2-acetamido-2-deoxy-beta-D-glucopyranose × 8 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1d3l 1p53 1p53

3 assemblies

Homodimer
1iam

1 assemblies

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1d3e 1d3e 1d3e 1d3e 1d3e 1d3i 1d3i 1d3i 1d3i 1d3i 1ic1 1ic1

37 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name ICA1_HUMAN
Isoform —
PDB entities 6
Chains and sequence ranges Author chain I； PDBConstruct 1–450； UniProt 28–477

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id1z7z
Deposition date deposition_date2005-03-28
Structure title titleCryo-em structure of human coxsackievirus A21 complexed with five domain icam-1kilifi
Keywords keywordsICAM-1, Kilifi, CD54, Human Coxsackievirus A21, virus-receptor complex, Icosahedral virus; Virus/Receptor
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

1z7z__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

1z7z__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 1010 1011 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

1z7z__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）0.00 Å
Rg (electron density)178.90 Å
Total Rg179.10 Å
Atom count529440
Residues67200
Excluded volume9414000 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 1z7z__assembly_1__model_1 360-MERIC （360） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 1z7z__assembly_2__model_1 hexameric （6） Excluded — —
Exclusion reason： Auxiliary symmetry representation; not a complete or representative biological assembly.
3 1 1z7z__assembly_3__model_1 30-meric （30） Excluded — —
Exclusion reason： Auxiliary symmetry representation; not a complete or representative biological assembly.
4 1 1z7z__assembly_4__model_1 36-meric （36） Excluded — —
Exclusion reason： Auxiliary symmetry representation; not a complete or representative biological assembly.
5 1 1z7z__assembly_5__model_1 hexameric （6） Excluded — —
Exclusion reason： Auxiliary symmetry representation; not a complete or representative biological assembly.
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (7)

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6. Fold Classification (SCOP + CATH) 5 domains

SCOP 2.08 (5 domains)

Domain ID domain_idd1z7zi1
Class classb — All beta proteins
Fold Fold foldb.1 — Immunoglobulin-like beta-sandwich
Superfamily Superfamily superfamilyb.1.1 — Immunoglobulin
Family Family familyb.1.1.3 — C2 set domains
Domain ID domain_idd1z7zi2
Class classb — All beta proteins
Fold Fold foldb.1 — Immunoglobulin-like beta-sandwich
Superfamily Superfamily superfamilyb.1.1 — Immunoglobulin
Family Family familyb.1.1.3 — C2 set domains
Domain ID domain_idd1z7zi3
Class classb — All beta proteins
Fold Fold foldb.1 — Immunoglobulin-like beta-sandwich
Superfamily Superfamily superfamilyb.1.1 — Immunoglobulin
Family Family familyb.1.1.4 — I set domains
Domain ID domain_idd1z7zi4
Class classb — All beta proteins
Fold Fold foldb.1 — Immunoglobulin-like beta-sandwich
Superfamily Superfamily superfamilyb.1.1 — Immunoglobulin
Family Family familyb.1.1.4 — I set domains
Domain ID domain_idd1z7zi5
Class classb — All beta proteins
Fold Fold foldb.1 — Immunoglobulin-like beta-sandwich
Superfamily Superfamily superfamilyb.1.1 — Immunoglobulin
Family Family familyb.1.1.4 — I set domains
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7. Citations (1)